RCTs of at least 6 weeks' treatment duration were eligible for inclusion. Databases including MEDLINE, Embase, CINAHL, and ClinicalTrials.gov were searched up to December 2022. Two reviewers were involved in all stages of the systematic review process. Squalane- A hydrocarbon that has an oily texture, it’s highly stable, moisturising and anti microbial Dermatica recommend one or two pumps twice a day (under sunscreen in the day). One pump is a good amount to cover the whole face. It has a heavy creamy texture but isn’t greasy at all. It doesn’t spread that easily, I feel that I need a little moisture with it to spread it well. If you know anything about me from my podcast or YouTube videos, you’ll know that I’m all about a hydrating mist to help my skincare layers absorb and with the Dermatica Azelaic 20% Cream I feel like I need a little spritz to smooth things along. It absorbs well with no pilling.

Azelaic acid: treats a myriad of skin concerns, like reducing the appearance of redness and breakouts, fading blemishes, and refining skin tone. A true powerhouse ingredient Cleanse your skin thoroughly to remove any dirt or makeup. Dermatica advises not using a washcloth or any exfoliating cleanser to avoid irritation Forty-three RCTs met the inclusion criteria. Meta-analyses within 20 rosacea studies demonstrated that erythema severity, inflammatory lesion counts, overall improvement, and treatment success (achieving skin clarity) were significantly improved with AA compared with vehicle after 12 weeks. AA was more effective than metronidazole 0.75% for improved erythema severity, overall improvement, and inflammatory lesion counts. Sixteen acne studies suggest that AA is more effective than vehicle for improving global assessments and reducing acne severity. AA 20% also significantly reduced more lesions than erythromycin gel. Within seven melasma studies, AA 20% was significantly better than vehicle for both severity and global improvement. AA 20% demonstrated significantly better results compared with hydroquinone 2% for global improvement. Very few significant differences between AA and comparators were observed for commonly reported adverse events. No eligible RCTs were found that evaluated skin aging. Adapalene, azelaic acid, and niacinamide have a powerful anti-inflammatory effect, reducing the redness and spots associated with rosacea. In addition, they combine to provide anti-ageing effects, improving the appearance of fine lines, wrinkles and pigmentation. Skincare steps and expectations during treatment In this blog post, I’m going to talk about what Dermatica is, how it works, what’s in my rosacea treatment, how my skin has tolerated it, whether there’s been any progress after 6 weeks, and if I recommend Dermatica. I’m also sharing an insightful before and after photo to show you my genuine results as well as an exclusive discount code for big savings on your very own skincare prescription.As my skin was dry and sore about 1 week in, I decided to stop using the prescription for about 3 days to let my skin recover. My skin is more on the oily side, so I don’t typically experience dryness. It felt really uncomfortable at this point. Once my skin had recovered, I only applied the prescription at night and every other day to allow my skin to build more tolerance.

Head over to Dermatica and choose your skin concern. There are treatments for acne, anti-ageing, hyperpigmentation, melasma, skin glow, and rosacea. So now we know who needs this and what it can do, let’s find out why you need this particular Azelaic Acid. Dermatica‘s first “over the counter” product has a more rounded ingredient list than most prescription skincare creams have, making it a real powerhouse. It combines a prescription strength concentration of a well studied dermatological treatment with some beneficial ingredients that work together to make this a great treatment moisturiser. I’ll break down what’s in there (aside from the obvious like water, texture enhancers, preservatives and Azelaic)- Topical azelaic acid (AA) is indicated for acne and rosacea, but there is some evidence for its use for other dermatological conditions.

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As you can see, the redness is much less noticeable in the after photo, particularly around my cheeks and chin. Considering that I don’t use the prescription in the morning and evening, I think the results are phenomenal. Dermatica describes rosacea as: “Rosacea is a cause of persistent redness around the cheeks, chin, nose and forehead, affecting around 10% of people.” If you’re a skincare enthusiast, you’ll likely have heard of Dermatica. It’s an online dermatology service that creates custom prescriptions based on your skin’s needs and personal skin goals. This innovative dermatology service has gained considerable popularity in the last few years. People are drawn to the concept of an easily accessible, personalised skincare prescription. All prescriptions are created uniquely for the individual. Prescriptions are continually personalised, based on the prescriber’s skin as it changes over time. How does Dermatica work?

Bit of history from my side- I suffer with acne and melasma. My melasma is kind of under control after using Hydroquinone and Tretinoin but I’m on a break from the Hydroquinone so I could do with some bonus depigmentation which know Azelaic is good for. I get nasty spots around my period and little spots around my lower face all month long, yey! If you are a fellow British acne sufferer, you will know the difficulty in getting hold of prescription strength acne treatments in the UK. You have to ask your GP, who may or may not be interested and who might decide to prescribe something you’re not too keen on. I found out years ago that Azelaic Acid is a reliable treatment for my acne and generally had a good effect on my skin all round, but I’ve not found it easy to get my hands on it. I’ve resorted to asking friends in other countries to send it to me (thank you Cristina!), because it’s not so difficult to get hold of elsewhere. So Dermatica have really made life easier for UK acne sufferers. Dermatica 20% Azelaic Acid Cream Review Why you need Azelaic Acid 20% in your skincare routine Dermatica is the fusion of a multidisciplinary team encompassing consultant dermatologists, pharmacists specialising in dermatology, GPs, clinical researchers and formulation scientists. Dermatica Dermatica says it uses the highest purity grades of azelaic acid for maximum effectiveness. This formula is enriched with glycerin and squalane to protect the skin barrier. Propanediol- An oily substance that creates a smooth vehicle for the actives and helps with penetration. It’s fine for sensitive and acne prone skin and helps to moisturiseDermatica says that when you first start a rosacea treatment, it’s normal to experience dryness. It says that if you don’t experience any dryness, this doesn’t mean your treatment isn’t working, so bear this in mind. Now although 20% is a high percentage for Azelaic Acid, I've not had any issues with sensitivity or over-exfoliation. I went straight to using this most 4-5 nights a week. Once I realised my skin was tolerating the cream well, I reintroduced my Vitamin A serum (Medik8 Crystal Retinal 10) to my routine. I've been using this in my PM routine, after cleansing and toning. One pump of the cream is more than enough to cover my face. It's a beautiful texture - it's lightweight, spreads easily and absorbs instantly. Azelaic Acid can often be difficult to formulate elegantly - it can often be gritty or hard to spread. Dermatica have absolutely nailed the texture of this - it's a pleasure to use and works well with the other products in my routine. The cream feels really nourishing without being greasy.

The Azelaic Acid 20% Cream is vegan and cruelty-free. This OTC azelaic acid cream is also free from alcohol and fragrance. It promises to: A 5 because, to my understanding, this is the first OTC azelaic acid in the UK offering a prescription-grade strength product.I also haven’t been using the prescription for that long. These sorts of treatments can take around 3 months for you to see any results, so to see such big improvements after 6 weeks is very encouraging.