Bioperine is a proprietary variety of piperine, which is a molecule that can help your body absorb other helpful ingredients. This supplement is actually used on its own more often than not, so having a supplement that includes both Bioperine and ALA is a huge deal and great if you want to boost your body as much as possible.

Alpha-lipoic acid 600mg - Bioregulator Company Alpha-lipoic acid 600mg - Bioregulator Company

Always consult your physician before taking alpha-lipoic acid or any other kind of supplement to keep yourself away from any possible side effects. Recommend Dosage In test-tube studies, alpha-lipoic acid has reduced markers of inflammation, including NF-kB, ICAM-1, VCAM-1, MMP-2, MMP-9, and IL-6 ( 30, 31, 32, 33). May lower heart disease risk factors It’s made inside the mitochondrion — also known as the powerhouse of cells — where it helps enzymes turn nutrients into energy ( 1). Alpha-lipoic acid might slow blood clotting. Taking alpha-lipoic acid along with medications that also slow blood clotting might increase the risk of bruising and bleeding. Al'-Zamil', M. K. and Brezheva, E. V. [Implication of alpha-lipoic acid preparations in the treatment of diabetic neuropathy]. Zh.Nevrol.Psikhiatr.Im S.S.Korsakova 2008;108(2):27-30. View abstract.

On the other hand, suppressing AMPK activity may increase the number of calories your body burns at rest. Thus, animals who took alpha-lipoic acid burned more calories ( 6, 7). Both human and lab studies suggest that alpha-lipoic acid slows the progression of Alzheimer’s disease by neutralizing free radicals and suppressing inflammation ( 24, 25, 26). First, antioxidant properties allow alpha-lipoic acid to neutralize free radicals and reduce oxidative stress, which is linked to damage that can increase heart disease risk ( 35). Can kids take ALA supplements? It’s not recommended for kids to consume ALA supplements. Very young children (under 24 months of age) who take ALA supplements with large doses may experience vomiting, unconsciousness, or even seizures. Avoid providing ALA supplements even to diabetic children without a doctor’s recommendation. You usually do not need to worry about side effects, but they may affect some people. Side effects are usually mild, such as skin rash. Long-term side effects of taking ALA supplements are unknown.

Alpha-Lipoic Acid (ALA) as a supplementation for weight loss Alpha-Lipoic Acid (ALA) as a supplementation for weight loss

Again, be sure to talk to your doctor to determine whether taking an ALA supplement makes sense. Depending on your diet, a single pill might be more than your body should consume. FAQ Kucukgoncu S, Zhou E, Lucas KB, Tek C. Alpha-lipoic acid (ALA) as a supplementation for weight loss: results from a meta-analysis of randomized controlled trials. Obes Rev. 2017;18(5):594-601. doi:10.1111/obr.12528 Alpha-lipoic acid may play a role in weight loss. One of the main benefits of taking alpha-lipoic acid is the weight loss tendency it has. Taking ALA daily at doses of 1800mg for 20 weeks can help in the reduction of weight. Mijnhout, G. S., Alkhalaf, A., Kleefstra, N., and Bilo, H. J. Alpha lipoic acid: a new treatment for neuropathic pain in patients with diabetes? Neth.J Med 2010;68(4):158-162. View abstract. Mittermayer, F., Pleiner, J., Francesconi, M., and Wolzt, M. Treatment with alpha-lipoic acid reduces asymmetric dimethylarginine in patients with type 2 diabetes mellitus. Transl.Res 2010;155(1):6-9. View abstract.Alpha-lipoic acid is also available as a supplement and can be found in many health stores and online. Supplements can contain up to 1,000 times more alpha-lipoic acid than foods ( 3). Lee, W. J., Lee, I. K., Kim, H. S., Kim, Y. M., Koh, E. H., Won, J. C., Han, S. M., Kim, M. S., Jo, I., Oh, G. T., Park, I. S., Youn, J. H., Park, S. W., Lee, K. U., and Park, J. Y. Alpha-lipoic acid prevents endothelial dysfunction in obese rats via activation of AMP-activated protein kinase. Arterioscler.Thromb.Vasc.Biol 2005;25(12):2488-2494. View abstract. Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. View abstract. Lee, T. and Dugoua, J. J. Nutritional supplements and their effect on glucose control. Curr.Diab.Rep. 2011;11(2):142-148. View abstract. Gianturco, V., Bellomo, A., D'Ottavio, E., Formosa, V., Iori, A., Mancinella, M., Troisi, G., and Marigliano, V. Impact of therapy with alpha-lipoic acid (ALA) on the oxidative stress in the controlled NIDDM: a possible preventive way against the organ dysfunction? Arch.Gerontol.Geriatr. 2009;49 Suppl 1:129-133. View abstract.