The starting or entering compound needing to be processed is referred to as the substrate and the resulting compound is known as the end product. Cofactors As you can see, it’s a complex system that relies on many pieces working well and in unison. This is why things like histamine intolerance are so prevalent. The good news is that once you’re aware of all these moving parts, identifying the reasons why your histamine levels are elevated is possible. How? By looking at how all the pathways and genes interact with each other. Understanding this takes time but you have the tools to help you succeed. The key is dedicating time to learning. Likewise, your genes are constantly producing documents about your gut lining, which is repaired and rebuilt every seven days. If you eat right and live right, you’re going to get away from genetic mutations and have a great document: “Keep that guy’s gut strong and healthy!” If you mess up your genes with poor diet and lifestyle, your document probably says something like: “Since this man is giving me so much extra work to do, I can’t focus on repairing his gut lining. He’s also not providing me the tools I need. So give this man a weak gut lining—the kind that lets food leak through.” Watch out for all the weight gain, immune issues, and other problems that are likely to follow! You can read Dirty Genes to get the full Soak and Scrub protocol, but it’s a good idea to make it a normal part of your wellness routine, once or twice a year. This is one of the best ways to make sure your genes are staying clean all year long. Resources for Optimizing Your Genes

Dirty Genes: A Breakthrough Program to Treat the Root Cause Dirty Genes: A Breakthrough Program to Treat the Root Cause

I experienced that kind of aha moment myself when I discovered that I have at least three significant SNPs. I finally understood something about why I’m so focused and determined—some might say obsessive! Remember the MTHFR symptoms I mentioned earlier? I also saw why I can suddenly become irritable at a moment’s notice, and why I react so intensely to certain chemicals and fumes. It was a relief to have this new understanding: things made sense to me in a way they never had before, plus I had some new solutions I could rely on. As you read this, you’ll have the chance to make the same kind of exciting discoveries about yourself. Weaknesses: food sensitivities, pregnancy complications, leaky gut syndrome, allergic reactions, the risk of more serious conditions such as autoimmunity 4. MAOA, the gene that affects mood swings and carb cravings The form of the DNA without any changes in amino acid sequence (i.e., without a SNP). Wildtype is usually found in the majority of the population. The symbol (-/-) indicates the wildtype version. Heterozygous – 1 copy of a SNP Dr. Ben Lynch also recommends a good brand of probiotics to keep our microbiome healthy. Some health conditions like headaches, runny nose, asthma and leaky gut is a sign that one may have histamine intolerance.Psychological stress: issues at work, at home, with your loved ones, with life The Clean Genes Protocol: How to Change Your DNA A dirty gene is born dirty via a SNP or becomes dirty from exposure to mold, chemicals or infection, The dirt impacts the ability of the gene to function properly.’ But there’s a problem. Trying to find out more about your genes—including your own specific genetic challenges—isn’t easy. You can easily be swamped by a mass of confusing information and contradictory recommendations that feel nearly impossible to sort through.

Dirty Genes by Dr. Ben Lynch — Seeking Health

GST/GPX ( detox ): These two genes have a strong influence on the body’s ability to collect chemicals and heavy metals and get rid of them. When they aren’t working as they should be, you can experience detox dilemmas, where your body becomes more toxic than it should be because it simply can’t take the garbage out. If your GST/GPX genes are dirty, then your glutathione levels are likely low. Because it plays a significant role in detoxification, low glutathione levels can lead to a reduced ability to eliminate harmful compounds. If toxins accumulate in the body, you might experience smell sensitivity, chlorine and deodorant intolerance, fatigue, brain fog, early graying of hair, and erratic moods. Dr. Ben Lynch also advises avoiding having carpets if you want to avoid having dirty genes. Because apparently, carpets are sponges that hold dirt. There are also a lot of other odd compounds in carpets. It traps dust and humidity, attracts molds and dust mites. Gas And Cooking

Lynch believes in this essence, but his own avatar, his own version of this belief system, is genetics. It’s certainly closer to science, but it is a gross oversimplification of a fascinating field. But do genes get dirty? Lynch uses the term as a simplistic analogy. What he means is that genes can malfunction. Genes are active stretches of DNA that contain the instructions to make proteins, which are tiny effectors in our body. If genes contain mistakes (referred to as “disease-causing variants”), the proteins they will produce will be too short, or missing a bit, or unable to adopt the right shape to perform their function like a wrench painted by Dalí. This much is true. Follow guidelines to keep indoor air clean, bearing in mind that indoor air is often

COMT Fast Support - Dirty Genes™ — Seeking Health COMT Fast Support - Dirty Genes™ — Seeking Health

This gene affects your body’s ability to produce phosphatidylcholine, an essential compound that you need to maintain cell membranes, bile flow, muscle health, and brain development. Supplements may provide necessary vitamins and cofactors especially during times when enzymes are working very hard – such as infections, physical or mental stress or chemical exposures. It is preferable to obtain as many nutrients as possible from the foods you eat. Supplements should only be used to ‘supplement’ the extra that you may need. Supplement literally means ‘to add to or enhance.’ Use supplements to enhance your healthy diet and lifestyle. When taking supplements, the right amount is needed otherwise the enzymes may work too fast or too slow.I don’t think he is saying it is NOT the genes; I think he is saying mutated genes are a contributing factor (hence, we have to work HARDER to stay healthy), and the more mutations we have, the greater the impact. Am I incorrect, Dr. Ben?’

Dirty Genes: A Breakthrough Program to Treat the Root Cause

Sometimes a SNP causes a minor change, but sometimes it can have a major impact. Most often a SNP reduces the ability of the enzyme to do its job. Yet sometimes the activity of an enzyme is increased by a SNP (this is the case for some COMT variants for example). Next up: Understanding the Pathways If this sounds complex, think about the fact that you can have many genes behaving dirty at the same time! When one gene is dirty, it can also influence the way that others function. This cascade effect can result in any number of health issues. Our genes require tools. Most of the tools come from the food that we eat. If we are providing our body with healthful, wholesome foods, our genes get the tools they can use to function. Such as protein, carbs, fats, vitamins, minerals, water, air, and sunlight,” said Dr. Ben Lynch. Avoid fermented foods, leftovers, or food that’s likely to contain excess bacteria if you find they trigger symptoms.

You can take all the supplements you want, but if you have metals, genes won't work well. Avoid metals like aluminum because they interfere with neurotransmitters in the brain,” said Dr. Ben Lynch.