A 12-week study in 97 people with type 2 diabetes examined how consuming broccoli sprout extract — equivalent to 150 µmol of sulforaphane — daily affected blood sugar levels ( 17).

When considering the role of glucosinolates for musculoskeletal health, sulforaphane has been studied most extensively in animal models. Historically, the understanding of the effects of glucosinolates on skeletal muscle comes from trials of their application in animal production settings, with results indicating that although growth performance may be affected, muscle had an improved antioxidant status and fatty acid profile ( Drażbo et al., 2019; Skugor et al., 2019). When sulforaphane was provided to male Wistar rats for 3days prior to performing exhaustive exercise, sulforaphane served as an indirect antioxidant in skeletal muscle, as measured by decreased tissue total antioxidant capacity in the vastus lateralis muscle. It was concluded that sulforaphane plays a vital role in modulating the muscle redox environment; ultimately creating favorable effects on muscle ( Malaguti et al., 2009). It was reported that type 2 diabetic mice receiving sulforaphane injections over 4week had greater grip strength, lean mass, and gastrocnemius mass ( Wang M. et al., 2020). These diabetic mice also presented with improved skeletal muscle fiber organization after sulforaphane treatment. It was proposed that sulforaphane may downregulate the expression of inflammatory and apoptotic associated proteins. Sulforaphane was also suggested to play a role in regulating mRNA levels of anti-inflammatory and oxidative related genes. Collectively, it was concluded that sulforaphane treatment could be protective against skeletal muscle disease in mice with type 2 diabetes. Mild side effects have been associated with sulforaphane supplements, such as an increase in gas, constipation, and diarrhea ( 17, 29). Consuming sulforaphane in amounts found in cruciferous vegetables is considered safe with few — if any — side effects ( 8).Broccoli extract may even be better than fresh broccoli for those with digestive problems. Some people experience pain, bloating, gas and other symptoms when they eat foods with high fiber. Since broccoli extract contains bioactive compounds without the fiber, you can get these nutrients without fear of side effects. Fights Stomach Ulcers Research has shown that some types of vegetables may have greater health benefits than others for certain health conditions, such as diabetes, cardiovascular disease, and cancer ( Cooper et al., 2012; Aune et al., 2017). This may be due to the presence of unique bioactive phytochemicals with potent health-related effects. Therefore, targeted recommendations surrounding the intake of specific types of vegetables with protective health benefits could assist in the reduction of non-communicable diseases.

So how does it work? Vitamin K also plays a role in how calcium is metabolized. While calcium is important for strong bones, it’s also needed to keep neuron connections firing, which reduces the risk of cognitive decline (x). Sulforaphane has been shown to have anticancer properties in a number of test-tube and animal studies, reducing both the size and number of various types of cancer cells ( 5, 6, 7). Nandini DB, Rao RS, Deepak BS, Reddy PB. Sulforaphane in broccoli: The green chemoprevention!! Role in cancer prevention and therapy. J Oral Maxillofac Pathol. 2020 May-Aug;24(2):405. doi: 10.4103/jomfp.JOMFP_126_19. Epub 2020 Sep 9. PMID: 33456268; PMCID: PMC7802872. Broccoli Sprout Extract, Capsule Shell: Hydroxy Propyl Methyl Cellulose, Magnesium Stearate, Silicon DioxidePositive effects of glucosinolates in relation to blood pressure have also been found in animal models ( Wu et al., 2004). Dried broccoli sprouts (200mg/day; ∼12μmol glucoraphanin/g dry weight) administered daily to spontaneously hypertensive stroke-prone (SHRSP) rats resulted in significantly decreased measures of oxidative stress [increased glutathione (GSH) and decreased oxidized glutathione (GSSG); GSH/GSSG ratio 10.6–14.0 compared with 4.0–7.2 with SHRSP rats on control diet], which was correlated with significantly lower blood pressure (20mmHg lower compared to control) and improved endothelial function ( Wu et al., 2004). Sulforaphane, the metabolite of glucoraphanin, was considered responsible for these changes. 10μmol/kg body weight sulforaphane administered to SHRSP rats over a 4-month period resulted in reduced blood pressure and prevented hypertension-associated vascular remodeling ( Senanayake et al., 2012). It has also been hypothesized that erucin, an analog of sulforaphane, may play a role in the antihypertensive effect seen with arugula ( Eruca sativa) ( Salma et al., 2018). A significant reduction in mean arterial pressure was reported in salt-induced hypertensive rats administered 10 and 30mg/kg E. sativa extract (40.33 ± 1.15 and 59.43 ± 0.77%mmHg, respectively) ( Salma et al., 2018). Harvard Health. (2019). Phytonutrients: Paint your plate with the colors of the rainbow. [Online]. Harvard Edu. Last Updated: 2019. Available at: https://www.health.harvard.edu/blog/phytonutrients-paint-your-plate-with-the-colors-of-the-rainbow-2 [Accessed 6 December 2022]. Santín-Márquez R, Alarcón-Aguilar A, López-Diazguerrero NE, Chondrogianni N, Königsberg M. Sulforaphane - role in aging and neurodegeneration. Geroscience. 2019 Oct;41(5):655-670. doi: 10.1007/s11357-019-00061-7. Epub 2019 Apr 2. PMID: 30941620; PMCID: PMC6885086. Do you eat enough vegetables every day? If you’re like most people, the answer is probably “no.” Whether you don’t have time to cook broccoli, or you simply don’t like its taste or texture, broccoli is nonetheless one of the healthiest foods out there. WM has previously received funding from the NHMRC, Clifford Craig Foundation, Cancer Council Queensland and university grants/fellowships from La Trobe University, Deakin University, University of Queensland, and Bond University, received industry funding and has attended events funded by Cobram Estate Pty. Ltd., received travel funding from Nutrition Society of Australia, received consultancy funding from Nutrition Research Australia, and has received speakers honoraria from The Cancer Council Queensland and the Princess Alexandra Research Foundation. NT has received funding from Deakin University for an Executive Dean’s Post-Doctoral Fellowship.

Broccoli sprouts are 3-4 day old broccoli plants that have a similar appearance to alfalfa sprouts, and a similar taste to radish. They’re incredibly high in antioxidants, vitamin C, calcium and fibre, as well as a compound called glucopraphanin, which is the precursor to a potent detoxifying chemical called sulforaphane. [3] Which Foods Are Highest In Sulforaphane? Raw vegetables have the highest levels of sulforaphane. One study found that raw broccoli had ten times more sulforaphane than cooked broccoli ( 2). We felt the Phytofare® Catechin Complex was such a potent ingredient with ultra high bioavailability, it would further enhance our product. Test results showed that Phytofare® delivered 10x higher levels of active phyto-nutrients into the blood. Delivers complete phyto-complexes. All eight green tea catechins were detected in the blood as opposed to just one or two as is present in generic extracts. Greatly prolongs the presence of the phyto-complexes in the blood. With most extracts, all traces are eliminated from the blood in just a few hours. With Phytofare® all eight catechins remained in in the blood at therapeutic levels after 24 hours, making it effective in “once a day” applications.

How To Take Broccoli Sprout Extract

But too much inflammation can affect the whole body, impairing circulation, digestion, cognition and many other necessary functions. It can cause a great deal of pain, and sometimes there’s no known cause for it. Despite these promising findings, more research is needed to determine whether sulforaphane could improve heart health in humans. May Have Antidiabetic Effects Broccoli extract contains the bioactive compounds found in the florets and stems of this healthful cruciferous vegetable. These nutrients include potassium, iron and vitamins A, C and K, among others. This fine powder is best added to drinks like orange juice or fruit smoothies, but you can also add it to sauces and dips. Mix broccoli extract powder in pesto, marinara or even salad dressing for a nutritious boost to meals. The Bottom Line