ColdZyme ® is intended to be used against colds during virus exposure and can shorten the cold if used early in the course of the disease. If only one assessment (morning or evening) was available on a day, the daily value was based only on the single assessment.

The primary objective was to evaluate the impact on quality of life during a common cold episode based on the primary endpoint defined as the AUC of WURSS-21 QoL composite sub-score over 8 days following start of symptoms.Based on the results of a previously conducted trial with the same investigational device in a comparable setting [ 14], n = 338 subjects (with n = 169 subjects per treatment group) was assessed as required for the primary confirmatory statistical analysis of the study. A positive difference between treatment groups was also seen for the subjects' assessments of global efficacy of the investigational product A robust safety profile for ColdZyme was demonstrated throughout the study. Innovative Scientific Concept of Topical Virus Glycoprotein Inhibitors Incorporated in Hyperosmotic Glycerol Revolutionizes Future Prospects in the Treatment of Viral and Bacterial Throat Infections. The second major secondary endpoint was defined as the number of days with concomitant treatment possibly affecting common cold symptoms assessed during the first 4 days for each subject, based on the diary entries. in both groups) of the subjects used concomitant treatment that might affect common cold symptoms on all four days.

The enzyme is extracted as a by-product in the preparation of cod and therefore does not burden the marine ecosystem. The incidence rates of TEAEs (treatment-emergent adverse events) in the ColdZyme group and the placebo group were comparable; 4. According to the International Olympic Committee Consensus Statement on Load in Sport and Risk of Illness it is estimated that about 50% of all acute illness in athletes during competitions and tournaments affect the respiratory tract [6] .

This means the packaging is plain, there is no mention of what product is inside your package and there is no mention of Chemist4U either. In addition, several safety endpoints were defined, including physical examination, vital signs and adverse events throughout the study, as well as global evaluation of tolerability by subjects and investigators at study end and assessment of device deficiencies at Visit 2 and Visit 3.

Their breakthrough formula is meticulously crafted to create a protective barrier against the viruses that cause colds, offering a proactive approach to respiratory health. With Coldzyme, you're not just treating symptoms – you're fortifying your immune system for a life less interrupted by the discomfort of seasonal illnesses. ColdZyme Mouth Spray reduces the risk of colds and can shorten the course of the disease if used at an early stage of the infection.reported a benefit with ColdZyme by rating efficacy as “very good” or “good” in the ColdZyme group as opposed to the placebo group (60. Respiratory viral infections, also known as the common cold, are the most common infections in humans.

The specific conditions for elite athletes who train hard are linked to a higher risk of being infected by common cold viruses [16] which might be caused by a post-exercise immune function depression after prolonged training.Between January and April 2019, 701 subjects were enrolled and randomly assigned to the ColdZyme group (n = 351) or the placebo group (n = 350). This trial was conducted between January and April 2019, prior to the global outbreak of SARS-CoV-2 [registered at ClinicalTrials. In the winter period of 2019, between January and April, 701 eligible subjects were recruited and randomly assigned to the ColdZyme group (n = 351) or the placebo group (n = 350). Both groups were allowed to use optional care (as”rescue” treatment) comprising paracetamol (acetaminophen), maximum 2 g/day, ibuprofen, maximum 400 mg/day or saline nose drops or spray, if needed for symptom relief.