Each time a cell divides, it must copy its genetic material with perfect precision. Accurate cell division is essential to overall health and especially our health as we age because cells the do not divide correctly can eventually mutate into cancer cells or other types of diseased cells. (p 79) The hard reality is 99% of these longevity books are premised on shaky science at best, and are outright promoting mistruths to sell dangerous health advice to vulnerable readers at worst. One of the most compelling aspects of the book is its exploration of geroscience, the interdisciplinary field that investigates the relationship between aging and age-related diseases. Dr. Barzilai contends that targeting the biological processes of aging could prevent or delay the onset of multiple chronic diseases simultaneously, transforming the way we approach healthcare. He emphasizes the potential of geroscience to revolutionize medicine, allowing us to live not only longer lives but healthier ones as well. Conclusion

Outlive: The Science and Art of Longevity eBook : Attia MD

Ultimately if you eat balanced nutritious meals, exercise, don't smoke, get restful sleep, don't stress too much, and are socially connected on a daily basis you'll live a healthy long life :) If you have a nice genome too :P In Part III of OUTLIVE The Science and Art of Longevity, Peter Attia presents a comprehensive set of tactics in five main areas to optimize healthspan and longevity. These tactics, based on evidence and practical wisdom, are designed to help people achieve their envisioned future selves at 90 and beyond. G]enes that have become altered as a result of your lifestyle can actually be passed down to the next generation. That means that the DNA each one of us receives from our parents is influenced not only by the lifestyle of our parents but also our grandparents and our great-grandparents and our great-great-grandparents" (p. 65) Pseudo-scientific mumbo-jumbo about “spiritual healing” and “natural remedies” and “ancient secrets” peddled by scammy TV doctors abounds on the shelves of bookstores the world-over. Nikola Tesla seemed quite normal as a kid. He developed a lot of phobias as an adult. Some were rational, as it was a time of disease, like now. Others were bizarre! He probably would have had a Dementia diagnosis later in life. He died of heart disease at a really old age (died age 81)! He is one of the longest lived scientists of his time. He is the only scientist of the time I am aware of that had studied nutrition and placed himself on a natural foods diet. Hertz (died age 36) and Maxwell (died age 48) did not live anywhere near as long as him.”Right now I’m reading sentence-by-sentence an utterly fascinating memoir that I’ll talk about early next week after I’m done reading it. Want to live a better life but feel overwhelmed? Longevity is achievable without sweat, without strict elimination diets, useless supplements, or pounding the pavement until you’re too sore to enjoy the rest of your day. Good news—living a longer and healthier life doesn’t need to be complicated.

Longevity… Simplified – Howard J. Luks, MD Longevity… Simplified – Howard J. Luks, MD

Loved it :) Feels like you're sitting down with Cameron Diaz and she really cares about your well being and wants to help you. I imagine us sitting in her chic apartment overlooking New York with a glass of red wine in our hands and she's teaching me a million things about ageing. (Inspired vision from the movie The Other Woman haha). LEAF is a 501(c)(3) non-profit organization dedicated to promoting increased healthy human lifespan through fiscally sponsoring longevity research projects, and raising awareness regarding the societal benefits of life extension. So if you want to age well, consider what makes you feel most alive. Consider what fills you with love and anticipation and wonder and joy - and then go and do some more of that, please." (p 204) Parietal: essential for skin sensations; injury can result in confusion about space, and inability to recognise things by touch and a general confusion about simple tasks, like getting dressed.The two major risk factors for Alzheimer's disease are age and gender: at age sixty-five and older, women have almost double the risk of Alzheimer's as men. Nearly two-thirds of Americans with Alzheimer's disease are women." (p. 189) At Abundance 360, David Sinclair made quite a number of encouraging comments about the future of aging research, including methods of resetting epigenetics to a youthful state. Emmett […]

9 Best Longevity Books for 2021 - Longevity Advice 9 Best Longevity Books for 2021 - Longevity Advice

Induced pluripotent stem cells (iPSCs) are mature cells that have been reprogrammed to become immature, embryonic-like cells capable of developing into specialised cells that can be used for treatment throughout the body. I like the way Cameron Diaz writes these scientific books in an approachable way. I also really enjoyed the little vignettes about her life and how she's put into practice what she has learned. The Golden Age by John C. Wright: In a post-singularity future where life extension technology has made every human effectively immortal, the theft of a portion of his memories sends Phaethon on a quest throughout the transformed solar system. A positive attitude in general increased your life expectancy, especially if you're positive about the ageing process. Mr. Kaminskiy is a co-founder and managing partner of Deep Knowledge Group - a consortium of commercial and non-profit organizations active on many fronts in the realm of DeepTech and Frontier Technologies (AI, Longevity, Precision Medicine, FinTech, GovTech, InvestTech), ranging from scientific research to investment, entrepreneurship, analytics, policy and philanthropy.I don't want you to live in fear of ageing, or beat yourself up about the fact that your body is doing something totally natural. I want to reframe the way that we, as women, talk about ageing. I want to offer a perspective that is healthier and more scientifically accurate than the fear and shame-based conversations that permeates our culture." (p. 5, Introduction) Here's how the mutations work: within our genome, we have some helpful genes called tumour suppressors that stop us [from] developing cancers. We also have some genes called proto-oncogenes that can promote cancers. In non-cancerous tissue, our genes produce active tumour suppressors and inactive proto-oncogenes (in other words, more of what helps you and less of what hurts you.) If a tumour suppressor gene is inactivated because of mutation, or a pro-oncogene mutates in a way that activates it, that cell can go on to divide uncontrollably, and develop into cancer" (p. 101) Ashwagandha supplements have become popular in recent years and are frequently touted as an important part of healthy lifestyles. Here is what the science says about this […] Our bodies weaken naturally, and ageing puts us at risk of a host of diseases, but a risk factor is not a diagnosis. It's a call to action ... Knowing the risks can empower us to become the architects of our own strength and resilience." (p. 40) The rate at which we age and the shifts that accompany ageing are unique for every person. We will age, but we will not all experience ageing the same way. Yet there are, generally speaking, some changes that will affect us all." (p. 67)