AIHW. Australia’s dental generations: the National Survey of Adult Oral Health 2004–06. Canberra: Australian Institute of Health Welfare; 2007. No. Although it is lactose free, it is derived from the milk protein, casein and therefore it should not be used on patients with milk protein allergies. Simmer JP, Hardy NC, Chinoy AF, Bartlett JD, Hu JC. How fluoride protects dental enamel from demineralization. J Int Soc Prev Community Dent. 2020;10:134–41. Lopatiene K, Borisovaite M, Lapenaite E. Prevention and treatment of white spot lesions during and after treatment with fixed orthodontic appliances: a systematic literature review. J Oral Maxillofac Res. 2016;7(2):e1.

Feldman M, Ginsburg I, Al-Quntar A, Steinberg D. Thiazolidinedione-8 alters symbiotic relationship in C. albicans- S. mutans dual species biofilm. Front Microbiol. 2016;7:140. Rahiotis C, Vougiouklakis G, Eliades G. Characterization of oral films formed in the presence of a CPP-ACP agent: an in situ study. J Dent. 2008;36:272–80. Treatment of post-orthodontic white spot lesions with casein phosphopeptide-stabilised amorphous calcium phosphate. The fact that you could only buy it from the dentist sort of made it a hassle to acquire (ID7, female, 65 years or older, dry mouth). The process of becoming a regular user of TMP Our results demonstrate that GC tooth mousse containing CPP-ACP does not inhibit planktonic growth of S . mutans at any of the concentrations tested, and even enhanced the number of viable bacteria after a 24 h incubation. The simultaneous presence of fluoride ions in the GCP tooth mousse showed a similar growth-stimulating effect at higher dilutions (0.3–1.25%), while at lower dilutions (2.5–5%), a 40–60% reduction in the viable bacteria was seen that seemingly is due to the fluoride ions known to exert anti-microbial activities [ 39]. An interesting observation was the dose-dependent elevation in ATP content in the bacterial samples grown with increasing doses of GC and GCP. The relative increase in ATP content was higher than the relative number of live bacteria after a 24 h incubation, suggesting that components in the tooth mousse may affect the metabolism of S. mutans, resulting in elevated ATP production. We suspected that CPP could be the component, since it is composed of peptides and phosphate groups, which can be utilized by the bacteria as nutrition. Indeed, we observed that CPP significantly increased the ATP content of the bacteria, with only minor effect on the planktonic growth. It is likely that other components of the tooth mousse are responsible for the increased proliferation of S. mutans. It is notably that the increase in ATP content by CPP was modest (1.5–3 fold) in comparison to the extreme increase in ATP content (25–40-fold) in samples exposed to GC/GCP. One possibility for the high ATP content detected in the latter samples could be the binding of ATP released from the bacteria to the tooth mousse texture.

Recensioni

A randomized single-blind parallel group trial comparing the effectiveness of daily application of MI Paste Plus® for 8weeks with a single application of 5% sodium fluoride varnish to a control group in improving the appearance of white spot lesions after orthodontic treatment.

Cachia M, Millward L. The telephone medium and semi-structured interviews: a complementary fit. Qual Res Organ Manag Int J. 2011;6(3):265–77. A qualitative study using Charmaz’s grounded theory methodology was conducted. Fifteen purposively sampled regular users of TMP were interviewed. Transcripts were analysed after each interview. Data analysis consisted of transcript coding, detailed memo writing, and data interpretation. Results Güçlü ZA, Alaçam A, Coleman NJ. Corrigendum to “a 12-week assessment of the treatment of white spot lesions with CPP-ACP paste and/or fluoride varnish.” Biomed Res Int. 2018;2018:1816959.

A single-blind clinical study to evaluate the remineralizing effect of Tooth Mousse® versus twice-daily brushing with fluoride toothpaste on enamel decalcification in orthodontics. Randomization of test and control group was not reported. The general decline in dental caries that has occurred may have led to some complacency amongst the dental team when considering the impact preventive care can have on patients. This conundrum is demonstrated in a study which found that 25 % of children initially caries free developed caries over the following three years and those with one carious lesion were five times more likely to develop more lesions when compared with those free of the disease [ 6]. Therefore professionals who only provide preventive advice to those with dental caries will be doing a disservice to many patients. Llena C, Leyda AM, Forner L. CPP-ACP and CPP-ACPF versus fluoride varnish in remineralisation of early caries lesions. A prospective study. Eur J Paediatr Dent. 2015;16:181–6. MI Paste Plus® to prevent demineralisation in orthodontic patients. A prospective randomised controlled trial.

Chen X, Daliri EB, Kim N, Kim JR, Yoo D, Oh DH. Microbial etiology and prevention of dental caries: exploiting natural products to inhibit cariogenic biofilms. Pathogens. 2020;9:569. Philip N, Walsh L. The potential ecological effects of casein phosphopeptide-amorphous calcium phosphate in dental caries prevention. Aust Dent J. 2019;64:66–71. Wilson TG Jr. How patient compliance to suggested oral hygiene and maintenance affect periodontal therapy. Dent Clin North Am. 1998;42(2):389–403. GC MI Paste Plus™ is a water-based creme containing RECALDENT™. Recaldent™ is gotten from the milk protein, casein. For a long time, it has been realized that milk and its subordinates have a tooth defensive impact. Research has demonstrated that this action is because of a piece of the casein protein called Casein Phosphopeptide (or CPP), which helps to restore minerals in teeth. Recaldent toothpaste restores enamel Beikler T, Flemmig TF. Oral biofilm-associated diseases: trends and implications for quality of life, systemic health and expenditures. Periodontol. 2011;2000(55):87–103.

GC MI Paste Plus

Remineralisation of occlusal white spot lesions with a combination of 10% CPP-ACP and 0.2% sodium fluoride evaluated using DIAGNOdent: A pilot study. Fernando JR, Butler CA, Adams GG, Mitchell HL, Dashper SG, Escobar K, et al. The prebiotic effect of CPP-ACP sugar-free chewing gum. J Dent. 2019;91:103225. Effects of casein phophopeptide amorphous calcium fluoride phosphate paste of white spot lesions and dental plaque after orthodontic treatment: a 3-month follow-up. b All except two [ 34, 39] of the nine studies reported on the regression of white spot lesions in orthodontic patients. This body of evidence, containing seven clinical studies [ 33, 35– 38, 40, 41] of variable strength of evidence utilised either visual scoring or fluorescence techniques for the assessment of dental caries. Some were compared with placebo pastes and others with different preventive products and/or control groups. Of these seven studies, four showed a significant advantage from the use of Tooth Mousse® in the regression of white spot lesions in orthodontic patients over 12weeks to 6months [ 33, 37, 38, 40]. GC Tooth Mousse is a topical, water based, sugar free cream that contains Recaldent CPP-ACP (casein phosphopeptides-Amorphous Calcium Phosphate). It is the first product for professional use to contain Recaldent. It also contains a blend of polishing, cleaning, scaling agents. This topical paste provides extra protection for teeth. Its aim is to deliver Recaldent to the oral cavity to restore the mineral balance to the oral environment.