Pico’s design of the Neo 3 Pro is still based on the predecessor. Due to the increase from two to four cameras, the arrangement has been changed. The cameras are no longer on the front of the glasses, but two in the upper and two in the lower corners of the headset. Kirkham JJ, Gorst S, Altman DG et al. (2016) Core Outcome Set–STAndards for Reporting: The COS-STAR Statement. PLoS: 21 Make sure you have 'Full cone NAT' or 'Open NAT' enabled in your router settings if such an option exists

By using the new Qualcomm Snapdragon XR2 processor, the Pico Neo 3 Pro achieves a significantly improved performance compared to its predecessor, the Neo 2, which still had the older Snapdragon 845 installed. Together with the increased refresh rate of 90 Hz, the content on the Pico Neo 3 Pro looks even smoother and more realistic. The Oculus Quest 2 has the same processor and also supports 90 Hz, but the VR experience is not as immersive as on the Pico Neo 3 due to the smaller field of view. Display of the Pico Neo 3 Pro

The best budget VR headset? Not for sure

What is the accuracy of clinical prediction models and tools (clinical history, cardiovascular risk factors, physical examination) in evaluating stable chest pain of suspected cardiac origin? Diagnostic prediction models can be used to inform who should be referred for further testing, whether treatment should be started directly, or to reassure patients that a serious cause for their symptoms is unlikely. Prognostic prediction models can be used for planning lifestyle or treatment decisions based on the risk for developing a particular outcome or state of health in a given period. In people with localised or locally advanced prostate cancer, which risk stratification models, tools and categorising systems perform better in indicating risk of poor outcomes? Depending on the type of review questions, the PICO framework may be appropriate but other frameworks can be used.

Craig P, Cooper C, Gunnell D et al. on behalf of the MRC (2011) Using natural experiments to evaluate population health interventions: new Medical Research Council guidance. London: Medical Research Council views and experiences of people using or providing services, family members or carers or the public on what constitutes a desired, appropriate or acceptable outcome Population: To which populations would the test be applicable? How can they be best described? Are there subgroups that need to be considered? What you won’t be getting, of course, is the same content library. As we’ll detail in a second, some of Quest 2’s best games are on the Neo 3 Link, but you obviously won’t have access to Meta-exclusive titles like Resident Evil 4 VR and Medal of Honor: Above and Beyond. It remains to be seen if Pico might support Neo 3 Link with its own exclusive software, though the company says there’s around 200 pieces of content on the device right now. Using informal committee consensus to make recommendations, without searching for evidence first. This is only likely to be suitable in situations where the development team is confident that no evidence is likely to exist that would help inform recommendations.

Petticrew M, Roberts H (2003) Evidence, hierarchies, and typologies: horses for courses. Journal of Epidemiology and Community Health 57: 527–9 When escalating from oxygen therapy, which non-invasive modality is most effective in adults in hospital with suspected or confirmed COVID‑19? Collins G, Reitsma J, Altman D et al. (2015) Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): the TRIPOD statement. Annals of Internal Medicine 162: 55–63 Craig P, Dieppe P, McIntyre S et al. on behalf of the MRC (2008) Developing and evaluating complex interventions: the new Medical Research Council guidance. London: Medical Research Council