Preliminary studies show that CoQ10 may slow, but not stop, the progression of Alzheimer's disease. Additional research is needed to confirm this effect. Research has shown that supplementing with CoQ10 reduces muscle pain in those taking statin medications.

Though these drugs are generally well tolerated, they can cause adverse side effects, such as serious muscle injury and liver damage. Those with heart conditions, such as heart failure and angina, may benefit from taking a CoQ10 supplement. CoQ10 supplements have been shown to improve muscle strength, vitality and physical performance in older adults ( 23). Weakened and enlarged heart (dilated cardiomyopathy). Early research suggests that taking coenzyme Q10 improves heart function in children and adolescents with dilated cardiomyopathy.Chest pain (angina). Some early research shows that taking coenzyme Q10 by mouth might reduce chest pain and improve exercise ability in people with chest pain. Dry mouth. Early research suggests that taking an altered form of coenzyme Q10 called ubiquinol improves dry mouth. Berio, A. and Piazzi, A. Improvement of Kearns-Sayre syndrome with controlled carbohydrate intake and coenzyme Q10 therapy. Ophthalmologica 1994;208(6):342-343. View abstract. A lung disease that makes it harder to breathe (chronic obstructive pulmonary disease or COPD). Early research suggests that taking coenzyme Q10 does not improve lung function or exercise performance in people with COPD. Do not use different forms of ubiquinone at the same time without medical advice. Using different formulations together increases the risk of an overdose.

Research on the effectiveness of CoQ10 for heart problems has provided mixed results. However, one study reported that CoQ10 was an important factor in the survival of older adults with chronic heart failure. Diabetes. Although more studies are needed, some research suggests that CoQ10 may help reduce low-density lipoprotein (LDL) cholesterol and total cholesterol levels in people with diabetes, lowering their risk of heart disease. Kidney failure. Some early research suggests that taking coenzyme Q10 improves kidney function in people with kidney failure. But it might not be helpful in people with less severe kidney disease. Bessler, H., Bergman, M., Blumberger, N., Djaldetti, M., and Salman, H. Coenzyme Q10 decreases TNF-alpha and IL-2 secretion by human peripheral blood mononuclear cells. J Nutr Sci Vitaminol.(Tokyo) 2010;56(1):77-81. View abstract. Research also has shown that Coenzyme Q10 is not likely to be effective in increasing athletic performance.Balercia, G., Mancini, A., Paggi, F., Tiano, L., Pontecorvi, A., Boscaro, M., Lenzi, A., and Littarru, G. P. Coenzyme Q10 and male infertility. J Endocrinol Invest 2009;32(7):626-632. View abstract. Ask a doctor, pharmacist, or other healthcare provider if it is safe for you to use Coenzyme Q10 if you have ever had: One thing to note is this supplement doesn’t have an absorption enhancer, which means you should take it with or after a meal that has healthy fat sources to ensure optimal absorption. There is currently not enough evidence to support using CoQ10 to either prevent or treat cancer or Parkinson’s disease. However, it might help treat certain heart conditions and prevent migraines. Arenas-Jal M, Suñé-Negre JM, García-Montoya E. Coenzyme Q10 supplementation: efficacy, safety, and formulation challenges. Compr Rev Food Sci Food Saf. 2020;19(2):574-594. doi:10.1111/1541-4337.12539

Collins GG, Rossi BV. The impact of lifestyle modifications, diet, and vitamin supplementation on natural fertility. Fertil Res Pract. 2015 Jul 25;1:11. doi:10.1186/s40738-015-0003-4 Coenzyme Q10 (PDQ)-Health Professional Version. National Cancer Institute. https://www.cancer.gov/about-cancer/treatment/cam/patient/coenzyme-q10-pdq#section/all. Accessed Oct. 18, 2020. It may be particularly useful for those looking to support their energy levels and/or heart health.Ubiquinone is a vitamin-like substance that is made naturally in the body. Ubiquinone is also known as Co Q-10, Coenzima, Ubidcarenone, Ubidécarénone, and Ubiquinol.