Dimidi E, Zdanaviciene A, Christodoulides S, et al. Randomised clinical trial: Bifidobacterium lactis NCC2818 probiotic vs placebo, and impact on gut transit time, symptoms, and gut microbiology in chronic constipation. Aliment Pharmacol Ther. 2019;49(3):251-264. View abstract. Further relevant studies: Gad et al., (2011), Johnson et al., (2011), Konieczna et al., (2013), Scully et al (2013) Symonds et al., (2012), van der Kleij et al., (2008), O’Mahony et al., (2005), Sheil et al (2007), Shanahan et al (2006), Sommerfield et al (2003), Symonds et al (2007), Wall et al (2010), von Wright et al (2002). Bifidobacterium infantis35624 and Mood Odamaki, T., Xiao, J. Z., Sakamoto, M., Kondo, S., Yaeshima, T., Iwatsuki, K., Togashi, H., Enomoto, T., and Benno, Y. Distribution of different species of the Bacteroides fragilis group in individuals with Japanese cedar pollinosis. Appl.Environ.Microbiol. 2008;74(21):6814-6817. View abstract. Von Wright A. et al (2002) ‘The survival and colonic adhesion of Bifidobacterium infantisin patients with ulcerative colitis’, International Dairy Journal, 12:197-200.

Moludi J, Khedmatgozar H, Saiedi S, Razmi H, Alizadeh M, Ebrahimi B. Probiotic supplementation improves clinical outcomes and quality of life indicators in patients with plaque psoriasis: A randomized double-blind clinical trial. Clin Nutr ESPEN 2021;46:33-39. View abstract. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178. View abstract. Quinlan, A. R. & Hall, I. M. BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics 26, 841–842, doi: 10.1093/bioinformatics/btq033 (2010).Predicted glycobiome of the Bifidobacterium genus and some additional members of the Bifidobacteriaceae family. Brenner D.M., & Chey W.D. (2009a), ‘ Bifidobacterium infantis35624: A novel probiotic for the treatment of IBS’. Rev Gastroenterol Disord. 9 (1):7-15. Foschia, M., D. P., Sensidoni, A. & Brennan, C. S. The effects of dietary fibre addition on the quality of common cereal products. Journal of Cereal Science 58, 216–227 (2013).

As some properties & benefits of probiotics may be strain-specific, this database provides even more detailed information at strain level. Read more about the strains that we have included from this genus below. Shanahan F. et al and Progid Investigators, (2006), ‘A one year, randomised, double-blind, placebo controlled trial of a Lactobacillusor a Bidifobacteriumprobiotic for maintenance of steroid-induced remission of ulcerative colitis’, Gastroenterology,130 (4 Suppl 2):A44.

Why choose us?

Wu G, Chen X, Cui N, et al. Preventive effect of Bifidobacterium supplementation on neonatal cholestasis in preterm neonates with very low birth weight. Gastroenterol Res Pract. 2020;2020:4625315. View abstract. Bairead E. el al.(2005), 'Alterations in immunological gene expression from colonic biopsies in female IBS patients following probiotic consumption'. Gastroenterology, 128(44) O’Mahony L, et al (2002), ‘Multi-organism comparison of probiotic performance in a murine model of Salmonella typhimurimuminfection’, Gastroenterology,122:T1337 Quigley E.M. et al (2005), 'Probiotic use results in normalization of bowel movement frequency in IBS: results from a clinical trial with the novel probiotic Bifidobacteria infantis35624’, Am J of Gastroenterology,100(9 Suppl S):S326 Tomoda T, Nakano Y Kageyama T. Variation in Small Groups of Constant Intestinal Flora during Administration of Anticancer or Immunosuppressive Drugs. Medicine and Biology(Japan) 1981;103(1):45-49.

Manzano S, De Andrés J, Castro I, Rodríguez JM, Jiménez E, Espinosa-Martos I. Safety and tolerance of three probiotic strains in healthy infants: a multi-centre randomized, double-blind, placebo-controlled trial. Benef Microbes 2017;8(4):569-578. View abstract. Misof, B. et al. Phylogenomics resolves the timing and pattern of insect evolution. Science 346, 763–767, doi: 10.1126/science.1257570 (2014). Sibartie S. et al (2009), ‘Modulation of pathogen-induced CCL20 secretion from HT-29 human intestinal epithelial cells by commensal bacteria’, BMC Immunol., 10:54. Sadeghi-Bojd S, Naghshizadian R, Mazaheri M, Ghane Sharbaf F, Assadi F. Efficacy of probiotic prophylaxis after the first febrile urinary tract infection in children with normal urinary tracts. J Pediatric Infect Dis Soc. 2020;9(3):305-310. View abstract.

Summary and Future Perspective

Charbonneau D.L. et al (2005d), ‘Fecal flora effects following oral supplementation with Bifidobacteria infantis35624 in healthy and IBS subjects’, Can J Gastroenterol. 19 (Suppl SB) pp.R1097. Sharif S, Meader N, Oddie SJ, Rojas-Reyes MX, McGuire W. Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants. Cochrane Database Syst Rev. 2020;10:CD005496. View abstract. Mohamad Nor MH, Ayob N, Mokhtar NM, et al. The effect of probiotics (MCP(®) BCMC(®) Strains) on hepatic steatosis, small intestinal mucosal immune function, and intestinal barrier in patients with non-alcoholic fatty liver disease. Nutrients 2021;13(9):3192. View abstract. Cremonini F, Di Caro S, Covino M, et al. Effect of different probiotic preparations on anti-helicobacter pylori therapy-related side effects: a parallel group, triple blind, placebo-controlled study. Am J Gastroenterol 2002;97:2744-9. View abstract. Bergey, D. H., Goodfellow, M., Whitman, W. B. & Parte, A. C. 1 online resource (2 v.) (Springer, New York, 2012).