Arnold LE, Christopher J, Huestis RD, Smeltzer DJ. Megavitamins for minimal brain dysfunction. A placebo-controlled study. JAMA 1978;240:2642-43.. View abstract.

Panthenol is suitable for all skin types including dry, oily, sensitive, combination and irritated skin.The test suggests that the skin that was pre-treated with panthenol was more resistant to irritants. And this explains why certain serums with active ingredients also incorporate vitamin B5 into the products to mitigate sensitivity and irritation. Panthenol not only treats irritation but also prevents it. Side Effects of Panthenol Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. To get the most out of your panthenol products, keep your skin type and concerns in mind. For example, if you’re looking to repair the damaged skin barrier, look for a minimal moisturizer that contains panthenol high up on the list. Panthenol is used in hair care products for its softening and strengthening properties. It can add moisture and protection to the hair shaft which can prevent breakage. It is also a great addition in hair products that aim to add a shine. How to use panthenol? Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. We avoid using tertiary references. We link primary sources — including studies, scientific references, and statistics — within each article and also list them in the resources section at the bottom of our articles. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

Panthenol isn’t just a moisture magnet; it’s also an anti-inflammatory agent. It can be effective in reducing redness caused by sun exposure or skin conditions, calming inflamed pimples, and relieving itchiness. Panthenol side effects Panthenol is a humectant. It binds water to the skin and increases the water content. As a result, it improves skin elasticity and keeps the skin plump and healthy. It prevents transepidermal water loss and keeps the outer layer of the skin hydrated. 2. It moisturizes.

StatPearls [Internet].

If you have a wound or irritated skin, panthenol can help. It plays a crucial role in promoting the growth of fibroblasts (the type of cells in the skin that produce skin-strengthening and wound-healing proteins). [3] [4] Soothes and calms Provitamin B5 also serves as a natural skin healer and protector. Skincare products containing Provitamin B5 help relieve the symptoms of irritated skin, such as itchiness, pain and discolouration. Provitamin B5 has also been known to speed up the healing process of wounded, recently tattooed or sun damaged skin. Products containing panthenol can also help soothe and protect infants against irritant diaper dermatitis. Panthenol is also a common ingredient in nipple creams to treat nipple trauma and pain in breastfeeding individuals. Improves hair health And because of its hydrating, moisturizing, and soothing benefits, panthenol is incredibly helpful in repairing the damaged skin barrier, treating irritation, and reducing sun-induced redness. 5. It prevents irritation. Dyslipidemia is another field that can potentially use vitamin B5. Since vitamin B5 is essential for the biosynthesis of coenzyme A, it plays a role in the metabolism of lipids. One study concluded that pantethine (a derivate of vitamin B5) lowered cardiovascular disease risk markers in low to moderate-risk participants. [10]These risk markers include LDL, HDL, and total cholesterol.

There aren’t many significant risks of using panthenol. The FDA considers panthenol to be a nutrient or dietary supplement that’s safe. Panthenol is a vitamin that can be used in topical treatments or taken as a supplement. Shibata, K., Fukuwatari, T., Watanabe, T., and Nishimuta, M. Intra- and inter-individual variations of blood and urinary water-soluble vitamins in Japanese young adults consuming a semi-purified diet for 7 days. J.Nutr.Sci.Vitaminol.(Tokyo) 2009;55(6):459-470. View abstract. Panthenol is an emollient that interacts with the lipids (such as ceramides) that form the protective barrier on the outer layer of the skin. So it has the ability to restore barrier function and reduce transepidermal water loss, which means your skin can retain more moisture and combat dryness. Encourages skin recovery

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Clinical studies have shown the evaluation of dexpanthenol in wound healing applications. These small clinical trials used the drug as a pastille and or spray to heal wounds in postoperative endotracheal intubation, endoscopic sinus surgery, and tonsillectomy. [7] [8] [9]The useof dexpanthenol shows better clinical outcomes in these clinical trials. Regardless, further studies are necessary to generalize drug efficacy. So this is how panthenol works in skincare and the best panthenol skincare products to try. It’s a no-muss, no-fuss ingredient that’s gentle enough to use on sensitive skin. So definitely give it a try. Webster MJ. Physiological and performance responses to supplementation with thiamin and pantothenic acid derivatives. Eur J Appl Physiol Occup Physiol 1998;77:486-91. View abstract.