At the determined cut of value of 12.7 mg/dl, urea was positive in only 12 cases of study group and negative in 52 cases. Among the controls 61 (95.3%) were truly negative for urea. Creatinine was positive in 31 (48.4%) of the 64 study group participants and falsely negative in 33 (51.6%) while of the control group, it was truly negative in 43 (67.2%) and falsely positive in 21 (32.8%). The k value of 0.875 of nitrazine showed that it was the most reliable test for predicting PROM, followed by creatinine 0.156 and finally urea at k of 0.141.

Some people’s water does break before contractions have started, but studies show the VAST majority will start into labor within 24-48 hours. Sensitivity, specificity, PPV, NPV, and accuracy of nitrazine test for PROM in this study were 87.5%, 100%, 100%, 88.9%, and 93.7%, respectively. This is similar but slightly higher than in the study by Agbara et al. in which nitrazine had an accuracy of 89.3%.[ 30] It was also comparable to the study by Haseli et al. with the values 94.1%, 90.5%, 98.2%, and 73.1%.[ 31]Unequivocally, yes. The test can often be done in their office (which is WAY faster than going into the hospital), so call them and see what they think you should do.

A larger percentage (65%), of PROM cases presented before 24 h of drainage while the remaining 35% presented after 24 h of drainage. This is similar to what was obtained by Sharma et al. and Khan et al. in which 91.6% and 61.67%, respectively, presented before 24 h of drainage.[ 6, 23] So, that’s the deal on an at home amniotic fluid test. Like I said — I guess it’s not a horrible idea to plan ahead to have at home but please talk with your doctor if that’s your plan. AND if you think you’re ruptured — it’s too late, call your doctor. Low amniotic fluid, also known as oligohydramnios, can occur due to various reasons other than the rupture of membranes. Tests that measure the levels of chemicals known to exist in the amniotic fluid but not in vaginal fluid. These include prolactin, alpha-fetoprotein, glucose, and diamine oxidase. High levels of these substances mean that the membranes have broken. Treatment. Amniocentesis might be done to drain amniotic fluid from the uterus if too much has built up — a condition called polyhydramnios.Being 35 or older. Babies born to people 35 and older have a higher risk of chromosomal conditions, such as Down syndrome. A health care provider might suggest amniocentesis to rule out these conditions if prenatal cell-free DNA screening is positive.