Altenburger MJ, Gmeiner B, Hellwig E, Wrbas KT, Schirrmeister JF. The evaluation of fluorescence changes after application of casein phosphopeptides (CPP) and amorphous calcium phosphate (ACP) on early carious lesions. Am J Dent. 2010;23(4):188–92. Davies RM, Davies GM, Ellwood RP. Prevention. Part 4: Toothbrushing: what advice should be given to patients? Br Dent J. 2003;195(3):135–41. Thepyou R, Chanmitkul W, Thanatvarakorn O, Hamba H, Chob-Isara W, Trairatvorakul C, et al. Casein phosphopeptide-amorphous calcium phosphate and glass ionomer show distinct effects in the remineralization of proximal artificial caries lesion in situ. Dent Mater J. 2013;32(4):648–53.

When TMP was first recommended to participants, despite not being pleased with the possibility of keep losing teeth, incorporating an additional step into their oral hygiene routine was not straightforward (Table 7)—as it is expected with any change of habit. However, they knew something had to shift if they sincerely wanted to keep their teeth. Feelings such as anxiety, uncertainty, determination, confidence, and reassurance were part of such process. Participants spoke about three main barriers: (a) being difficult to apply TMP daily, (b) TMP not being available at chemist/pharmacy and (c) TMP being an expensive product. Ren Y, Jongsma MA, Mei L, van der Mei HC, Busscher HJ. O

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Strontium chloride doesn’t treat the root cause of the sensitivity and so you may develop tooth sensitivity again in the future. Look at the active ingredients. In the US Sensodyne and Pronamel have one of two active ingredients: potassium nitrate, stannous fluoride or Novamin. I have split these into a helpful table below. If one ingredient isn’t working for you, try switching to the other. The active ingredient is the main difference with the pastes. Urobte pre svoje zuby niečo navyše. Remineralizačný ochranný krém GC Tooth Mousse je navrhnutý tak, aby posilnil odolnosť zubov voči vonkajším vplyvom a zamedzil ich nadmernej citlivosti. Vďaka obsahu mliečneho proteínu RECALDENT™ poskytne zubom vysokú dávku vápnika a fosfátu. Tým dochádza k posilneniu zubnej skloviny, celkovej revitalizácii a uzavretiu precitlivených dentálnych tubulov. Streptococcus mutans is a common cariogenic bacterium in the oral cavity involved in plaque formation. Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) has been introduced into tooth mousse to encourage remineralization of dental enamel. The aim of this research was to study the effect of tooth mousse containing CPP-ACP (GC Tooth Mousse®) or CPP-ACP with 0.2% fluoride (CPP-ACPF; GC Tooth Mousse Plus®; GCP) on S. mutans planktonic growth and biofilm formation. Následne krém nechajte pôsobiť 3 minúty a potom ho jazykom rozotrite v celých ústach a nechajte takto pôsobiť ďalšie 1 – 2 minúty. Snažte sa neprehĺtať. Následne krém vypľujte a ústa nevyplachujte. Zvyšok krému na povrchu zubov sa postupne sám vytratí. Nejedzte a nepite 30 minút od aplikácie.

Charmaz's iteration of the constant comparative method was used during data analysis [ 27]. This involved coding of interview transcripts, detailed memo writing and drawing diagrams. The transcripts were analysed as soon as possible after each interview. Coding and interpretation of data was conducted by AS, a trained researcher with PhD and experience of qualitative research and grounded theory methodology [ 28]. Team meetings were held where AS, GGA and ECR discussed data analysis findings and compared their interpretations. To put it bluntly, there isn’t one single best Sensodyne toothpaste. Other than two different active ingredients, there isn’t an awful lot of difference in the formulations, but there may be a big change in price.Evans RW, Pakdaman A, Dennison PJ, Howe EL. The caries management system: an evidence-based preventive strategy for dental practitioners. Appl Adults Aust Dent J. 2008;53(1):83–92. Our results demonstrate that GC tooth mousse containing CPP-ACP does not inhibit planktonic growth of S . mutans at any of the concentrations tested, and even enhanced the number of viable bacteria after a 24 h incubation. The simultaneous presence of fluoride ions in the GCP tooth mousse showed a similar growth-stimulating effect at higher dilutions (0.3–1.25%), while at lower dilutions (2.5–5%), a 40–60% reduction in the viable bacteria was seen that seemingly is due to the fluoride ions known to exert anti-microbial activities [ 39]. An interesting observation was the dose-dependent elevation in ATP content in the bacterial samples grown with increasing doses of GC and GCP. The relative increase in ATP content was higher than the relative number of live bacteria after a 24 h incubation, suggesting that components in the tooth mousse may affect the metabolism of S. mutans, resulting in elevated ATP production. We suspected that CPP could be the component, since it is composed of peptides and phosphate groups, which can be utilized by the bacteria as nutrition. Indeed, we observed that CPP significantly increased the ATP content of the bacteria, with only minor effect on the planktonic growth. It is likely that other components of the tooth mousse are responsible for the increased proliferation of S. mutans. It is notably that the increase in ATP content by CPP was modest (1.5–3 fold) in comparison to the extreme increase in ATP content (25–40-fold) in samples exposed to GC/GCP. One possibility for the high ATP content detected in the latter samples could be the binding of ATP released from the bacteria to the tooth mousse texture. Andersson A, Skold-Larsson K, Hallgren A, Petersson LG, Twetman S. Effect of a dental cream containing amorphous cream phosphate complexes on white spot lesion regression assessed by laser fluorescence. Oral Health Prevent Dent. 2007;5(3):229–33.

The initial literature search on CPP-ACP yielded a huge number (7576) of publications, however a close scrutiny of the results identified 172 articles that were worthy detailed inspections. Ultimately, 20 articles were selected but eight studies (Table 2) were excluded, giving just 12 papers to consider, three focusing on prevention and nine on controlling dental caries.Actual whitening treatments can cause tooth sensitivity, but what about whitening toothpastes you can use at home? Well bear in mind that these will only remove stains, and will not lighten the overall colour of your teeth. But they may still give you the results you want. Given that oral health care advice is a key part of the dental service for patients it is important to consider the evidence for the effectiveness of our preventive activities. We want to be confident we can maintain good oral health and reduce the risk of caries. Different toothpastes do have different active ingredients for sensitivity. You need to give them a couple of weeks to see if they do have an effect. Tooth Mousse Plus® (MI Paste Plus®) contains 900 parts per million fluoride in a molar ratio with the calcium and phosphate of 5 calcium, 3 phosphate and 1 fluoride which is reported by Reynolds and co-workers as the ideal ratio for building fluorapatite [ 18, 19]. You may want to avoid stannous fluoride containing toothpastes if you are concerned about staining. Generally, stannous fluoride is linked to staining on teeth, also manufacturers claim they can reduce this effect with the correct formulation.