What we know: SAM-e is an effective anti-inflammatory and analgesic for people with OA. Results may be felt in just one week but could take more than a month. SAM-e works closely with vitamins B-12, B-6 and folate, so it is important to get enough of the B vitamins when taking this supplement.

Glucosamine Complex w/ Chondroitin, MSM, Turmeric - Bettervits

Claims: Reduces pain and inflammation, improves joint function and slows progression of osteoarthritis (OA). Curcumin tea or latte may be effective in fighting cancer. Some researchers hypothesize that it can reduce a cancer patient’s risk of metastasis (tumor spreading to other body parts). Dosage: Most capsaicin products – such as Zostrix,ZostrixHP,Capzasin-P and others – contain between 0.025 to 0.075 percent concentrations. Apply regularly three times daily. Kongtharvonskul J, et al. (2015). Efficacy andsafety of glucosamine, diacerin, and NSAIDs in osteoarthritis of the knee. DOI:Studies: A 2014 Cochrane Review found that a three-month course of 100 mg a day of enriched (AKBA) Boswellia reduced OA pain by nearly 20 points and improved function byeight points (on 100-point scales) without serious side effects. In a 2018 systematic review of 20 OA supplements, Boswellia extract was among the standouts, providing significant short-term relief for knee, hip and hand pain. The Natural and Alternative Treatments database, which contains over 12,000 clinical studies, also gives Boswellia high marks for OA pain relief.

Glucosamine vs. Turmeric: Which is Better for Joint Health?

Origin: One of numerous compounds known as cannabinoids in the cannabis plant. Unlike THC, it does not have an intoxicating effect.Origin: The leaves and stem of the stinging nettle plant, a stalk-like plant found in the U.S., Canada and Europe. Researchers have indicated that the curcumin content of turmeric helps stabilize blood sugar levels. Since curcumin may help manage blood sugar levels, it can help with fat loss. Curcumin also boosts metabolism, which means burning more calories. Although St. John’s wort taken alone is considered safe, it is potentially dangerous if taken with prescription antidepressants. We've included a mixture of other essential compounds such as Boswellia Serrata and Vitamin C, which can help contribute to the normal function of bones. With upward of 3.6% of the global population living with this debilitating condition, many people use or have tried using combined glucosamine and chondroitin supplements to alleviate osteoarthritis pain ( 2). Summary

Glucosamine Chondroitin 180 Capsules with Turmeric, Ginger Glucosamine Chondroitin 180 Capsules with Turmeric, Ginger

Studies: A randomized, placebo-controlled trial of 184 adults showed two tablets per night for 28 nights produced significant improvements in sleep and quality of life. In the same review, the supplement was not found to improve joint mobility or function compared with a placebo ( 11). Glucosamine and chondroitin together Though the two can be taken separately, glucosamine and chondroitin are commonly taken as a single supplement. This combination has been more extensively studied. Claims: Relieves pain and inflammation, improves joint mobilityinosteoarthritis (OA),rheumatoid arthritis (RA),juvenile idiopathic arthritis (JIA)and scleroderma, and manages amyloidosis (excessive build-up of protein in organs as seen in RA). Increases blood flow to skin. Wu D, et al. (2013). Efficacies of differentpreparations of glucosamine for the treatment of osteoarthritis. DOI:

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What we know: St. John’s wort’s mood-elevating properties were believed to be from active ingredients hypericin and hyperforin, chemicals that raise levels of serotonin, a chemical found in the brain. Serotonin levels may be low in people who are depressed and possibly in those whohave fibromyalgia. New research, however, suggests the whole preparation (not just the two active ingredients) is more effective. Daily JW, et al. (2016). Efficacy of turmericextracts and curcumin for alleviating the symptoms of joint arthritis. DOI: Turmeric helps improve blood flow to and from the heart, encouraging antiplatelet activity that can help prevent clogged arteries. Since it is rich in antioxidants, it helps manage cholesterol levels. It also eases any swelling in the heart and is good for the heart’s overall health.