The aim of this prospective observational study was to evaluate the efficacy of a universal strategy of primary prevention of preterm birth using intravaginal chlorhexidine (CLX) applied before 16 weeks. The main question is whether universal treatment with vaginal CLX before 16 weeks would reduce the incidence of preterm birth, especially before 34 weeks. Participants were recruited at the routine first trimester consultation. All patients underwent an initial ultrasound examination between 6+0 and 15+6 weeks gestation, including assessment of embryo/fetus vitality. Antiseptic treatment aimed at reducing possible bacterial overgrowth consisted of 10 days (1 box) of CLX vaginal ovules (CLX digluconate 0.2%) always starting between 9+0 and 16+0 weeks. As this product is widely marketed and frequently indicated in gynaecology, we did not deprive the non-treated group of treatment because we wanted to assess whether it could have an effect on reducing preterm delivery. The pregnant women were then followed up until the end of pregnancy and compared with a cohort of patients who had not received any treatment. All data related to delivery were collected, as well as any events related to preterm delivery, such as onset of contractions, cervical shortening and premature rupture of membranes, regardless of final gestational age at delivery.

Extractul de Hamamelis si musetel protejeaza mucoasa vaginala si reduc inflamatia vaginului. Mai contine clorhexidina si vitamina E. Box Now κοστίζει 2,30€ για παραγγελίες με μέγιστο βάρος 20 κιλά και διαστάσεις έως 62 x 45 x 36 cm.

Study Plan

Finally, preterm birth incidence was calculated for specific groups selected according to the multivariable analysis result. Statistical analysis and graphs were done using Graph Pad Prism®, Mac version 9.0.1, and Stat Plus® Mac Pro version 8.0.1.s. Participants were recruited at the routine first trimester consultation. All patients underwent an initial ultrasound examination between 6+0 and 15+6 weeks gestation, including assessment of embryo/fetus vitality. Group 1: pregnant women who received intravaginal chlorhexidine before 16 weeks of gestation Group 2: pregnant women who did not received intravaginal chlorhexidine e before 16 weeks of gestation Pe viitor de cate ori veti lua antibiotic folositi ovule antimicotice si ar fi bine sa luati si iumostimulatoare, mai ales in peiroadele stresante. Este posibil sa va ajute: Ginexid Ovule - FarmaDerma (de la FarmaDerma)

The main question is whether universal treatment with vaginal CLX before 16 weeks would reduce the incidence of preterm birth, especially before 34 weeks. Hydeal-D ® 0,2% (derivat al acidului hialuronic cu eliberare prelungită). Alte componente: gliceride de origine vegetală, metilpropandiol, 1,2-hexandiol, caprilil glicol, apă purificată, acid lactic. Nu conţine parabeni sau alte tipuri de conservanţi As this product is widely marketed and frequently indicated in gynaecology, we did not deprive the non-treated group of treatment because we wanted to assess whether it could have an effect on reducing preterm delivery.Type of event triggering preterm birth:Premature rupture of membranes /Uterine dynamics + cervical modifications In cazul dumneavoastra, daca nu mai aveti mancarimi si secretii colorate (alb branzos, galben sau gri),urmati un tratament de 7 zile cu Zenella (1 comprimat dimineata, unul seara), apoi asteptati cateva zile si refaceti analizele de secretie vaginala. Este posibil sa va fi vindecat, dar secretia vaginala sa nu fie inca de consistenta si aspect normale din cauza afectiunilor prelungite. Brown RG, Marchesi JR, Lee YS, Smith A, Lehne B, Kindinger LM, Terzidou V, Holmes E, Nicholson JK, Bennett PR, MacIntyre DA. Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin. BMC Med. 2018 Jan 24;16(1):9. doi: 10.1186/s12916-017-0999-x. Citations Reporting on Results Patients with vaginal bleeding during the first trimester.– Patients with abnormalities detected in the first trimester ultrasound scan.– Twin pregnancies– Patients with a known allergy to the topical use of Chlorhexidine in any of its forms of presentation.

Spear GT, French AL, Gilbert D, Zariffard MR, Mirmonsef P, Sullivan TH, Spear WW, Landay A, Micci S, Lee BH, Hamaker BR. Human alpha-amylase present in lower-genital-tract mucosal fluid processes glycogen to support vaginal colonization by Lactobacillus. J Infect Dis. 2014 Oct 1;210(7):1019-28. doi: 10.1093/infdis/jiu231. Epub 2014 Apr 15. gr προσφέρουμε την δυνατότητα επιστροφής σε όλα τα προϊόντα, για την ανταλλαγή ή την πλήρη επιστροφή χρημάτων μέσα σε 14 ημερολογιακές ημέρες από την ημέρα παράδοσης των προϊόντων με βάση τα έγραφα παραλαβής, με την προϋπόθεση ότι αυτά τηρούν τους πιο κάτω όρους.

Efectul tonic si revigorant al extractului de Hamamelis il recomanda pentru utilizarea in zonele sensibile si delicate. Brown RG, Marchesi JR, Lee YS, Smith A, Lehne B, Kindinger LM, Terzidou V, Holmes E, Nicholson JK, Bennett PR, MacIntyre DA. Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin. BMC Med. 2018 Jan 24;16(1):9. doi: 10.1186/s12916-017-0999-x.

presence of regular uterine contractions associated with cervical modifications (dilatation and/or shortening of the cervix) before 37 weeks

Finally, to assess the validity of results and ensure consistency an additional multivariable analysis was performed adjusting for clinical parameters, to evaluate the odds ratio (OR) of the different determinants in the prediction of preterm birth. Aveti nevoie in primul rand de un tratament care sa restabileasca echilibrul florei vaginale, de exemplu Zenella med, care contine inulina, benefica bacteriilor sanatoase din flora vaginala. The approximate number of births per year in Spain is 370,000. The minimum number of patients to be recruited would be 400 with a 95% confidence interval. Ginexid ovule este dedicat igienei intime; are efect emolient si protector prin restabilirea balantei fiziologice. courier, είτε με την υπηρεσία Box Now, μπορείτε να χρησιμοποιήσετε την υπηρεσία Box Now ώστε να ολοκληρώσετε την αποστολή προς εμάς από την κοντινότερη θυρίδα σας.