Lemsip injection is indicated for the management of mild to moderate pain, the management of moderate to severe pain with adjunctive opioid analgesics, and the reduction of fever.

Taking Lemsip alongside other medicine containing paracetamol can cause an overdose, potentially resulting in serious liver and kidney damage. [1]If you take Lemsip max flu lemon in the hour before or the six hours after taking colestyramine, the paracetamol is likely to be less effective. This is because colestyramine reduces the absorption of paracetamol from the gut. An overdose of paracetamol is dangerous and capable of causing serious damage to the liver and kidneys. Never exceed the recommended dose of Lemsip max flu lemon. Get immediate medical advice in the event of an overdose with this medicine, even if you feel well, because of the risk of delayed, serious liver damage. The antidiabetic medicines exenatide, lixisenatide and liraglutide may slow down the absorption of paracetamol into the bloodstream, so Lemsip max flu lemon might take longer to work if you are using one of these medicines to treat your diabetes. Ask your pharmacist for more advice.

Lemsip was not found to be mutagenic in the bacterial reverse mutation assay (Ames test). Despite this finding, acetaminophen tested positive in the in vitro mouse lymphoma assay as well as the in vitro chromosomal aberration assay using human lymphocytes. In published studies, acetaminophen has been reported to be clastogenic (disrupting chromosomes) when given a high dose of 1,500 mg/kg/day to the rat model (3.6 times the MHDD). No clastogenicity was observed at a dose of 750 mg/kg/day (1.8 times the MHDD), indicating that this drug has a threshold before it may cause mutagenesis. The clinical relevance of this finding in humans is unknown. Peak blood levels of free acetaminophen are not reached until 3 hours after rectal administration of the suppository form of acetaminophen and the peak blood concentration is approximately 50% of the observed concentration after the ingestion of an equivalent oral dose (10-20 mcg/mL). When deciding whether to take a medicine during pregnancy, it's important to find out about the possible effects of that medicine on your baby. Chronic, excessive consumption of alcohol may increase the risk of acetaminophen-induced hepatotoxicity, which has included rare cases of fatal hepatitis and frank hepatic failure requiring liver transplantation.Don't take Lemsip max flu lemon if you have taken a type of medicine called a monoamine oxidase inhibitor (MAOI) in the last 14 days. MAOIs include the antidepressants phenelzine, tranylcypromine, isocarboxazid and moclobemide, and the anti-Parkinson's medicines selegiline and rasagiline. This is because the combination of pseudoephedrine with these medicines could cause a dangerous increase in blood pressure (hypertensive crisis). Find sources: "Lemsip"– news · newspapers · books · scholar · JSTOR ( September 2014) ( Learn how and when to remove this template message) Medicines called decongestants cause the most concern for people who have high blood pressure. Decongestants help open a stuffy nose. The medicines narrow blood vessels, which can reduce swelling in the nose area and other parts of the body. But it's harder for blood to Understanding over-the-counter medications and high blood pressure. American Heart Association. https://www.heart.org/en/health-topics/high-blood-pressure/changes-you-can-make-to-manage-high-blood-pressure/understanding-overthecounter-otc-medications-and-high-blood-pressure. Accessed Feb. 8, 2023. If you take paracetamol in the hour before or the six hours after taking colestyramine, the paracetamol is likely to be less effective. This is because colestyramine reduces the absorption of paracetamol from the gut. You should avoid taking Lemsip max capsules one hour before or six hours after taking colestyramine.

Soothe your throat. To treat a sore or scratchy throat, gargle with warm salt water. You also could try drinking warm water with lemon juice and honey. Or try menthol cough drops. It's not known if phenylephrine passes into breast milk, or its effect on a nursing infant. When taken by mouth, decongestants such as phenylephrine can also temporarily decrease the production of breast milk with just one or two doses. Lemsip max should not be used by woman who are breastfeeding. Ask your doctor or pharmacist for further advice. Lemsip max cold and flu capsules should be used with caution in: Lemsip Max Day & Night Cold & Flu Relief Capsules. Lemsip Max All in One Lemon. Lemsip Max All in One Wild Berry and Hot Orange. Lemsip Max All in One Cold & Flu Capsules. Lemsip Max All In One Liquid. Lemsip Max Flu Lemon. For Cold & Flu relief. Contains Paracetamol.According to its FDA labeling, acetaminophen's exact mechanism of action has not been fully established - despite this, it is often categorized alongside NSAIDs (nonsteroidal anti-inflammatory drugs) due to its ability to inhibit the cyclooxygenase (COX) pathways. It is thought to exert central actions which ultimately lead to the alleviation of pain symptoms. Alcohol increases the risk of liver damage that can occur if an overdose of paracetamol is taken. The hazards of paracetamol overdose are greater in persistent heavy drinkers and in people with alcoholic liver disease. The Professional Standards Authority for Health and Social Care (PSA) provides information on qualified or registered practitioners. This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. The binding of acetaminophen to plasma proteins is low (ranging from 10% to 25%), when given at therapeutic doses.