Primary care prescribers encouraged to prescribe by brand name to avoid unlicensed specials being dispensed. Colecalciferol and its metabolites are excreted in breast milk. Overdose in infants induced by nursing mothers has not been observed but allowance for any maternal dose should be made when prescribing vitamin D products to a breast-fed child. May be used orally for reversal of excessive anticoagulation. See SFH warfarin guidelines or NUH guideline on the management of excessive coumarin anticogulation in adults Intramuscular (IM) Injection = as per Notts APC Alcohol Dependence Guidelines. May be administered in primary care by appropriately trained professionals using the correct administration technique.

Colecalciferol is metabolised by microsomal hydroxylase to form 25-hydroxycolecalciferol (25(OH)D 3, calcidiol), the primary storage form of vitamin D 3. 25(OH)D 3 undergoes a secondary hydroxylation within the kidney to form the predominant active metabolite 1,25-hydroxycolecalciferol (1,25(OH) 2D 3, calcitriol). The metabolites circulate in the blood bound to a specific α-globin.No new patients to receive prescriptions in primary care. Patients already receiving Red Medicines in primary care should be handled on a case by case basis with the support of the Medicines Optimisation team. Suspension 500mg of dl-alpha-tocopherol acetate (500 units) in 5ml.(See tableof liquid medicines requiring dose adjustment) Many brands containing lutein include: ICaps®, Macushield®, MaculEH Light®, Ocuvite®, PreserVision®, Vitalux Plus®, Viteyes®.

Because Vitamin D promotes calcium absorption, it is important for bone mineralization (hardening), which keeps your bones strong and supple. A sufficient amount of Vitamin D helps prevent joint pain and osteoporosis. Treatment of vitamin D deficiency: 1-4 capsules (1 000- 4 000 IU) daily for 10 weeks dependent upon the severity of the disease and the patient's response to treatment, followed by maintenance therapy of 1-2 capsules (1 000- 2 000 IU) daily, as directed by your doctor.

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Vitamin D plays an important role in bone building by enabling calcium uptake by your body. It is also very important for healthy immune system function and may help lower your risk of contracting colds. Vitamin D also helps confer innate immunity which may protect your body from the influenza virus.

Tablets disperse in water if needed. See here for general advice on dispersing tablets. Liquid can be made specially if required - SFH: send patients to KMH pharmacy for suppliesDosing doesn’t fit with local Vitamin D guidelines. Formulary options for Vitamin D products will be reviewed alongside the guideline update. For use in alcohol dependence see Notts APC Alcohol Dependence Guidelines. Note that use in alcohol dependence is not well supported by evidence, see RMOC info here and NHS England info here. If you are unsure whether Valupak Vitamin D 3 is safe for you, speak to your doctor or ask a pharmacist for advice. Who Should Not Take Valupak Vitamin D 3?