A paper published in 2021 suggests that gum periodontal disease is revealing itself as more complex than ever.

For heaven’s sake, if this is all about bacteria, then why can’t you just treat it with antibiotics? Mice without active succinate receptors were more resilient to disease,” said Dr Fangxi Xu, an assistant research scientist in the Department of Molecular Pathobiology at NYU Dentistry and the study’s co-first author. The researchers developed a gel formulation “of a small compound that targets the succinate receptor and prevents it from being activated”.In short, they have developed a prototype gel that people could rub on their gums at home and avoid all that sweaty deep cleaning. Cellular Stimulation: DentiZen™ stimulates cellular activity in the gums, promoting the regeneration of gum tissue. The active ingredients work synergistically to activate key cellular processes involved in collagen synthesis, which is crucial for restoring the strength and elasticity of the gums. I am delighted with Gengigel. My gums have been a problem for some time on my lower teeth, not anymore! Using metabolomic analyses, they found higher succinate levels in the samples from people and mice with gum disease. Strengthening Gum Attachment: One of the key goals of DentiZen™ is to strengthen the attachment between the gums and the teeth. By promoting cellular regeneration and collagen production, the gel helps restore the proper gum attachment, preventing further gum recession and enhancing overall gum health.

The researchers are continuing to study the gel in animal models to find “the appropriate dosage and timing for application, as well as determine any toxicity”.Week 2: I continue to notice improvements in my gum health and the overall appearance of my smile. My gums feel firmer and stronger, and I can see that they're gradually regaining their natural position. It's truly remarkable how is working to reverse the effects of gingival atrophy. I'm feeling more confident and optimistic about my oral health every day. Thanks to Gengigel, my toothbrush is no longer bloodstained. For years this has worried me as I have a fear of losing my remaining lower teeth – have lost all from Pyorrhea (wish I’d had Gengigel years ago).

Strengthening Gum Attachment: One of the key goals of DentiZen™ is to strengthen the attachment between the gums and the teeth. By promoting cellular regeneration and collagen production, the gel helps restore the proper gum attachment, preventing further gum recession and enhancing overall gum health. I have been using Gengigel and feel compelled to share my experience with other customers. Throughout the past ten years I have had problems with bleeding and rapidly receding gums. I cannot believe the difference that using Gengigel has made. My gums are healthy, do not bleed and best of all, the exposure of the join on my crowns has disappeared – this has made it very easy to measure the effect of using the product. I am so grateful to have been able to obtain Gengigel and will continue to use as well as recommending to others. Inflammation Reduction: Inflammation is a common issue associated with gum disease and can contribute to gingival atrophy. contains anti-inflammatory compounds that help reduce gum inflammation, alleviating discomfort and creating a more conducive environment for gum regeneration.Whatever answer the dentist gives you probably won’t satisfy. They’ll talk about inflammation and tissue damage and then shrug. Online shopping can seem daunting. We want you to know that there is absolutely zero risk of purchasing something. We won’t make it difficult if you don’t love it. I think Gengigel is wonderful. For some years I have had severe problems with my gums. It was so bad that my gums would bleed even when eating soft food, and they were red and swollen all the time. Both the doctor and the dentist could offer me no solution. After a few days of discovering Gengigel I was able to clean my teeth with no bleeding and after two weeks my gums even looked normal. Something at last that really works. I can’t thank you enough for this product. The NYU team, in a new paper, describe research that “lays the groundwork for a non-invasive treatment for gum disease that people could apply to the gums at home to prevent or treat gum disease”.

My journey to finding a solution for my receding gums was filled with frustration and disappointment until I stumbled upon DentiZen™. This remarkable gel not only stopped the progression of gum recession but also worked wonders on the overall health of my gums. The transformation has been astounding. I now have healthier, more resilient gums that have surpassed my expectations. DentiZen™ has become an essential part of my daily oral care routine, and I couldn’t be happier with the results. If you’re feeling hopeless about your receding gums, trust me, DentiZen™ is the answer you’ve been searching for.” Inflammation Reduction: Inflammation is a common issue associated with gum disease and can contribute to gingival atrophy. DentiZen™ contains anti-inflammatory compounds that help reduce gum inflammation, alleviating discomfort and creating a more conducive environment for gum regeneration. My gums were bleeding in one place when I brushed my teeth, as well as several gums receding and one tooth becoming loose. Since using Gengigel daily for several months, my gums no longer bleed when I brush my teeth, and my loose tooth has stabilised and now very nearly solid. Thank you for your wonderful product.When the researchers administered extra succinate to both types of mice, the gum disease worsened in the normal mice (those with the intact succinate receptor).