Apply a thin layer of the cream onto the skin and massage gently. Use 2-3 times a day. Keep out of reach of children. Store below 25C Patients affected by advanced AMD, central macular atrophy with unstable fixation and best corrected visual acuity (BCVA) between 20/100 and 20/320 were considered. Selected patients underwent fundus photography and microperimetry with fixation analysis for the selected eye (highest BCVA). Ten consecutive training sessions of 10 min each were performed twice a week in the selected eye with Retimax Vision Trainer (CSO, Florence). BCVA, reading acuity and reading speed, contrast sensitivity, fixation, retinal sensitivity and quality of life questionnaire (VFQ-25) were evaluated at baseline and 7 days following the final session. Malaria.Taking vitamin A by mouth seems to decrease malaria symptoms in children less than 3 years-old living in areas where malaria is common. Breast cancer.Premenopausal women with a family history of breast cancer who consume high levels of vitamin A in their diet seem to have reduced risk of developing breast cancer. It is not known if taking vitamin A supplements has the same benefit. The extension of retinal dysfunction is quantified very accurately, particularly in the early stages of disease.

Diarrhea related to HIV.Taking vitamin A along with conventional medicines seems to decrease the risk of death from diarrhea in HIV-positive children with vitamin A deficiency. Measles.Taking vitamin A by mouth seems to reduce the risk of measles complications or death in children with measles and vitamin A deficiency.

Central Nervous System: irritability, headache, and increased intracranial pressure as manifested by bulging fontanels, papilledema, and exophthal-mos. Acute toxicity to vitamin A can occur when adults or children ingest >100x or >20x the RDA, respectively, over a period of hours or a few days. The RDA for vitamin A differs depending on age and sex and can range from 300 - 900 μg retinol activity equivalents (RAE) per day. Symptoms of acute systemic toxicity generally include mucocutaneous involvement (e.g. xerosis, cheilitis, skin peeling) and may involve mental status changes. Children are typically more susceptible to acute vitamin A toxicity - daily intakes of as little as 1500 IU/kg have been observed to result in toxicity. Eye disease affecting the retina (retinitis pigmentosa).Research suggests that taking vitamin A can slow the progression of an eye disease that causes damage to the retina. Recovery from laser eye surgery (photoreactive keratectomy).Taking vitamin A by mouth along with vitamin E seems to improve healing after laser eye surgery.

Automated adjustment of subtended visual angle depending on the optical correction applied to the patient The following amounts have been found to be toxic orally. Toxicity manifestations depend on the age, dosage, size, and duration of administration. Retimax 1500 Protective Ointment with Vitamin A, is the strongest preparation of this type on the market, tested dermatologically and microbiologically. Ointment can be safely used even by persons prone to allergies and children, eg. With diaper dermatitis. Protective Ointment with Vitamin A, creates in the skin, normal collagen type VII, building fiber anchor that improve connectivity between the epidermis and dermis. Vitamin A also stimulates the increase in the number of new blood vessels in the skin and protects it against damage. Additionally ointment great nourishes, moisturizes and nourishes the skin and is recommended especially for the skin extremely dry, irritated and flaky. Tones the skin and makes the irritated skin becomes soft and smooth. Adult: 1 million Units daily for three days; 50,000 Units daily for longer than 18 months; 500,000 Units daily for two months. Hypervitaminosis A Syndrome Retimax 1500 is a cream that contains Vitamin A and is extremely safe even for allergy sufferers. The Retimax 1500 perfectly nourishes, moisturises, firms and protects the blood vessels. Works well on excessive dry skin and dehydrated skin by toning the skin and softening and smoothing irritated skin. Retimax is the strongest preparation of this type on the market. Tested dermatologically and microbiologically. This cream is safe to be used by persons prone to allergies and children. Can also be used as an excellent remedy for nappy rash dermatitis and a treatment for burns and frostbite.Vision:Retimax (all- trans retinol) is converted in the retina to the 11- cis-isomer of retinaldehyde or 11- cis-retinal. 11- cis-retinal functions in the retina in the transduction of light into the neural signals necessary for vision. 11- cis-retinal, while attached to opsin in rhodopsin is isomerized to all- trans-retinal by light. This is the event that triggers the nerve impulse to the brain which allows for the perception of light. All- trans-retinal is then released from opsin and reduced to all- trans-retinol. All- trans-retinol is isomerized to 11- cis-retinol in the dark, and then oxidized to 11- cis-retinal. 11- cis-retinal recombines with opsin to re-form rhodopsin. Night blindness or defective vision at low illumination results from a failure to re-synthesize 11- cis retinal rapidly.

Significant improvements in terms of BCVA [ p = .011], reading speed [ p = .007], VFQ-25 score [ p = .007], retinal sensitivity [ p = .021] and fixation stability in the central 2° and 4° [ p = .048; p = .037] post-treatment were observed for the 9 patients enrolled, with insignificant improvements observed in reading acuity and contrast sensitivity [ p = .335; p = .291]. Complications after pregnancy.Taking vitamin A seems to reduce the risk of diarrhea and fever after pregnancy in malnourished women. Systemic: hypomenorrhea, hepatosplenomegaly, hepatotoxicity, jaundice, leukopenia, vitamin A plasma level over 1,200 Units/100 mL. Cataracts.Research suggests that high intake of vitamin A in the diet is linked to a lower risk of developing cataracts.

Complications during pregnancy.Taking vitamin A by mouth seems to reduce the risk of death and night blindness during pregnancy in malnourished women. Precancerous lesions in the mouth (oral leukoplakia).Research suggests that taking vitamin A can help treat precancerous lesions in the mouth.