In the body, chronic stress frequently causes inflammation.The anti-inflammatory qualities of ashwagandha may assist in lessening the inflammatory reaction brought on by stress and lessen its detrimental effects on general health. Magnesium’s mechanism of action Despite its numerous benefits, keep in mind that ashwagandha may also lead to some adverse reactions. Side effects of ashwagandha are rare but may include nausea or stomach problems, including diarrhea and vomiting. Magnesium is a mineral that the human body cannot synthesize. Magnesium is an important mineral in nutrition because it helps regulate nerve impulses, muscle contractions, and blood glucose levels. It also plays a key role in helping produce energy within cells. Additionally, magnesium deficiencies have been linked to mood swings, insomnia, tremors, and more. Side Effects The large list of ashwagandha health benefits includes relieving stress, aiding sleep, increasing energy levels and improving concentration. 8

While high doses of niacin may help to lower cholesterol, studies show that if you already take a statin drug, adding high-dose niacin does not appear to provide additional benefit and may carry serious risks. Nevertheless, some physicians believe taking niacin in addition to statin medication may be helpful for certain people; however do not try this combination without consulting your physician. Kaushik, M. K., Kaul, S. C., Wadhwa, R., Yanagisawa, M., & Urade, Y. (2017). Triethylene glycol, an active component of ashwagandha (Withania somnifera) leaves, is responsible for sleep induction. PloS One, 12(2), e0172508. Some of the most absorbable forms of magnesium are its organic salts, such as magnesium bisglycinate .National Library of Medicine, Biotech Information The National Center for Biotechnology Information advances science and health by providing access to biomedical and genomic information. View Source naturally present in the herb may bring on sleepiness. Other researchers propose that ashwagandha acts on GABA receptors A more balanced and calm mood may be promoted by adequate magnesium levels, which may assist moderate these stress hormones [ 2].

An experience of more peaceful sleep may be supported by adequate magnesium levels, which may aid in relaxing and serenity. What are the mechanisms of action when comparing ashwagandha and magnesium for stress relief? Unfortunately, most people do not consume enough of this mineral with diet alone because of modern processing and refining methods, which have depleted modern foods of this mineral. Gamma-aminobutyric acid (GABA) is one neurotransmitter in the brain that ashwagandha has an impact on [ 3].An inhibitory neurotransmitter, GABA helps people unwind and feel less anxious. A magnesium deficiency can result in muscle cramps, twitching, and overall discomfort. Numerous studies have demonstrated the benefits of magnesium in relieving muscle cramps and improving muscle function (6). Sleep and Relaxation

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A healthy female individual should consume 310-320mg of magnesium per day, and males around 400-420 mg, which covers food intake as well. Staying in this range will ensure safety with oral magnesium consumption since there are no major adverse effects of taking this mineral on a regular basis. It is important to consult a medical professional to determine the appropriate dosage and ensure safety. Individual response and experimentation They may evaluate your health profile, go through any possible interactions or contraindications, and suggest the best path toward stress alleviation. The combination of magnesium, which induces relaxation through the NMDA receptors, and ashwagandha, which activates the GABA receptors, will be able to ease up and unwind much better. More traditional Ayurvedic treatments use the entire dried root of the ashwagandha plant, which is turned into powder and usually steeped in milk.

National Library of Medicine, Biotech Information The National Center for Biotechnology Information advances science and health by providing access to biomedical and genomic information. View Source : Nowak, L., Bregestovski, P., Ascher, P., Herbet, A., & Prochiantz, A. (1984). Magnesium gates glutamate-activated channels in mouse central neurones. Nature, 307(5950), 462–465. https://doi.org/10.1038/307462a0 Magnesium aids in reducing the harmful effects of prolonged stress by encouraging a healthy stress response. The potential synergy of ashwagandha and magnesium combined Ashwagandha is available in multiple forms. It comes as a powder, tea, pill, tincture, or gummies. The price can depend on the brand, quantity, and quality. Ashwagandha products may also be mixed with other herbs or vitamins. Ashwagandha also doesn’t fall behind with research. A 90-day Ashwagandha supplementation helped to improve memory, reduce stress, sharpen focus, and improve self-perceived well-being.So, both ashwagandha and magnesium can offer benefits surrounding stress and anxiety. Ultimately, it’s up to the individual to decide which one is best for them. Some consumers may even opt to take the pair them together for a synergistic effect. Can You Take Magnesium and Ashwagandha Together? For example, studies show that magnesium is required for the activation of another important micronutrient - vitamin D3 [4] . On the other hand, vitamin D3 is important for better absorption of calcium. Ashwagandha, or Withania Somnifera, is a powerful adaptogen known for its ability to help you cope with stress. The combination of magnesium and Ashwagandha helps you maintain a positive mood, healthy heart, and strong immune system. Does Ashwagandha interact with Magnesium? Research determined that magnesium deficiency can very much worsen oxidative stress and can be detrimental to regular sleep patterns. Proper supplementation with magnesium citrate showed significant improvements. There is some evidence that ashwagandha supplements may cause liver damage. If you experience any side effects, especially symptoms consistent with liver damage such as jaundice or itchy skin, call your doctor immediately.

U.S. Food & Drug Administration. Mixing medications and dietary supplements can endanger your health. Ashwagandha ( Withania somnifera), also known as “Indian Winter cherry” or Indian Ginseng,” is an evergreen shrub that’s found in India, Africa and parts of the Middle East.Kumar, G., et al. (2015). Efficacy & safety evaluation of Ayurvedic treatment ( Ashwagandha powder & Sidh Makardhwaj) in rheumatoid arthritis patients: A pilot prospective study.