Got the book three days ago. Read the whole thing. Very impressive. Loved the dry wit humor. Now have to re-read it to understand it a little better. Loved the biochemistry/endocrinology. As Shakespeare’s Henry V said; “We few, we happy few . . .” – I’ve done the ‘few’ bit, but how can I get to ‘happy’? They tell me that when I own nothing I will be happy, but I’m not convinced yet. Since I first read your musings about clotting being the root cause of cardiovascular disease, it just seemed right. I don’t think I’m alone in being permanently stressed by the insanity of responses to the covid ‘threat’ all over the world. The global obsession with jabbing entire populations has fractured our social networks and families. My wife’s brother refuses to speak to us & has decided that we are ‘anti-vaxxers’. He doesn’t ‘do’ science, so proper conversation was impossible in any event. I was amazed that for a man of age 60, a systolic BP of 160 only reduces his life expectancy by 1.5 years compared to his having a systolic pressure of 120! If I started getting readings like that, I would have been screaming for an emergency ‘meeting’ with my GP. That figure puts the BP risks into a very different perspective!

The Clot Thickens by Dr. Malcolm Kendrick - by RootCause MD The Clot Thickens by Dr. Malcolm Kendrick - by RootCause MD

Bestselling author Elly Griffiths invites expert guests to lift the curtain on everything you want to know about the world of crime fiction. If you love a good murder mystery, then this is the podcast for you. The plaque grows – due to deposition of new blood clots on top of the existing plaque (which has become a point of clotting vulnerability)

The highest quintile of total red meat intake was associated with an 8% higher risk for stroke, but this was driven mainly by processed red meat (which was associated with a 12% higher risk for stroke). These findings are “generally consistent with cohort studies showing that processed meat, as with most highly processed foods for that matter, are associated with an increased risk of cardiovascular events,” Mente noted. Sorry not to buy from other sources but at my age difficult to fit more physical books in the house.

The Clot Thickens: The enduring mystery of heart disease The Clot Thickens: The enduring mystery of heart disease

Ellie proves to be a very natural interviewer and teases out fascinating details from her interviewees. Plus she drops done great teasers - the Ruth books have just been optioned for the 5th (?) time for tv. Surely they’ll go to the final stage this time and get filmed. There’s an avid audience gif them out here. It might explain why sportsmen are keeling over, as they probably have larger blood vessels to feed the oxygen hungry muscles”.

the plot thickens

An interesting quote from a 2006 novel by Linda Fairstein where one of the characters was electrocuted: This regulation can control the movement of the largest molecule, down to the very smallest. Including tight control of the entrance, and exit, of single atoms e.g., sodium, or potassium, or calcium (in truth, in the body, these atoms exist as ions – which is just the name for a charged atom). Just played 18 holes of golf. Apart from 3 stupid putts I scored 82. That is 3 over my age. Not boasting or anything, but I am convinced that the one factor our good Doctor did not mention was genetics.

The Clot Thickens by Malcolm Kendrick | Waterstones

This is a 150-year detective story with a cast of unrecognised heroes who may, finally, become known for their work on the true causes of heart disease. Exploring the truth about cholesterol – the apparently tried, and convicted, cause of millions of deaths from heart disease – with billions spent each year on lowering cholesterol with diet and drugs. Probably most of us here had the same experience, loosing friends and family members over Covid and the vaccines. I was quite surprised how ugly those who were against getting a vaccine turned on the unvaccinated after they decided to get the jab to be able to “participate in the economy”, as our Premier says (we live in Victoria, Australia). I think this is because in a sense they “sold themselves” and did not feel good about, and since people do not get angry at themselves for too long, they turned that anger on the unvaccinated. Up the point “they [the unvaccinated] should not be admitted to a hospital, they deserve to die if they’re refusing to get vaccinated”. English–Arabic English–Bengali English–Catalan English–Czech English–Danish English–Hindi English–Korean English–Malay English–Marathi English–Russian English–Tamil English–Telugu English–Thai English–Turkish English–Ukrainian English–Vietnamese In the same way, calling cardiovascular disease “multifactorial” is just a clever sounding way of describing a pile of stones. There is no structure, no understanding, no hypothesis. You seemed to go hot and cold about alcohol consumption. You said that the body consumes alcohol as its preferred fuel – thus causing it not to consume all its glucose. I thought I had read from you or someone that although alcohol contains a lot of calories these are just wasted (maybe as heat?). Looking it up, I see that alcohol dehydrogenase does indeed produce NADH as it oxidises alcohol.Many of them do eventually, within the span of the studies, become insulin dependent. Quelle surprise. Sulfonylureas put the beta cells under similar excessive free-radical stress as does carbohydrate chronically in excess of individual tolerance causing type 2 diabetes. They die off slowly by apoptosis. Another unpopular notion (with MDs). But this is simply a fact. I have studied enough of the clinical evidence to state this with confidence. And it should not be surprising to anyone who understands much about the working of the beta cells. OK, that is the beta cell, which is unusually susceptible to overstress and apoptosis via excessive OxPhos using glycolytic pathways and substrate (i.e. pyruvate). I’m sure a lot of people would agree that we live in strange times. But do they have to be so strange that Area 51 is making headlines? And what’s this about fish the look like aliens. September’s Words in the News explain all.

The Clot Thickens: The enduring mystery of heart disease

As the Blaxploitation craze comes to an end, Pam fights for better roles and hobnobs with the biggest names in showbiz. She meets the love of her life, a hot young comedian named Freddie Prinze -- whose personal demons lead to heartbreak and tragedy. But what is not accepted, will simply not be accepted, is that the arrival of a blood clot on the ‘healthy’ arterial wall is what initiates atherosclerotic plaque formation. Instead, it is almost universally accepted that it is LDL that does this, and LDL alone. Therefore, current conventional wisdom is that we have a three-step process: I admit I had somehow not realised that the significance of lp(a), is that it is so similar to LDL that it can be mistaken for LDL in analyses of plaques, but it performs a totally different function – being part of the clotting process no less. I have always found Authors a fascinating breed of people. Looking at life in a slightly different way from us normal mortals. But I did find one thing strange when you were discussing with Lesley and William about what your main characters looked like . I’m a reader that likes to be given a little idea on how the writer sees that character, not detailed but just an idea , small , large , fair , dark , short , tall . It makes me feel as if the writer has some sort of a image in their mind . That they have given that character flesh and bones .

so much of this nonsense happening in this world today when boiled down by the likes of Dr Zalenko and Dr Malone and many, many others (including our Doc) reveals the obvious truth. In the end, you cannot just bring a whole bunch of wildly different factors together, declare that cardiovascular disease is ‘multifactorial’, and everything is now, officially, sorted. No need to look further. Move on, nothing to see here.