It is recommended to take other medications at least one hour before, or four hours after taking Hunger Buddy. Adjust dosage with reference to a healthcare professional. The incidence of adverse side effects being reported was very rare (0.01%). These hypersensitivity reactions were typical of food allergies, like rash, itching, slight swelling and mild gastrointestinal upset. In such cases, treatment should be discontinued. Proprietary ingredient clinically shown to increase satiety and support significant weight loss in overweight and obese adults As demonstrated by Zaluvida Group’s research and evidenced in InQpharm’s three bmiSMART products, efficacious, safe and easy to apply approaches to weight management do exist. They also allow adaption to individual dietary habits (such as preference for fatty foods or carbohydrate-rich diets) and can help to overcome initial hunger sensations while individuals are transitioning to a healthier diet. During the intervention period, no significant changes in fasting blood glucose and HbA1c levels were observed between the study groups. 67% of subjects in the IQP-AE-103 high-dose group had a reduction in triglyceride levels compared with 37% in the placebo group ( ). Changes in total/low-density lipoprotein (LDL)/high-density lipoprotein (HDL) cholesterol were not significant at the end of the study, but a post hoc subgroup analysis performed with subjects with baseline total cholesterol level above 6.2 mmol/L revealed pre-post reductions in total cholesterol of 1.22 ± 1.10 mmol/L ( ), 0.58 ± 0.90 mmol/L ( ), 0.13 ± 0.31 mmol/L ( ), and reductions in LDL cholesterol of 1.18 ± 1.06 mmol/L ( ), 0.49 ± 0.74 mmol/L ( ), and 0.23 ± 0.29 mmol/L ( ), in high-dose, low-dose IQP-AE-103, and placebo groups, respectively.

Direct comparisons of IQP-AE-103 with other weight loss agents that affect dietary fat absorption such as chitosan, Litramine®, or orlistat are difficult for methodological reasons. Ho et al. reported that there were no significant changes from baseline in body weight after 12 weeks of treatment with chitosan [ 39]. A treatment with Litramine® (a proprietary fibre complex) led to 3.8 kg weight loss after 12 weeks of intake [ 17]. As for orlistat (gastric and pancreatic lipase inhibitor), a study by Anderson et al. reported a 3.05 kg weight loss in overweight subjects after 16 weeks of treatment at 180 mg per day [ 40], whereas at higher dose of 360 mg per day, it caused a body weight reduction of 8.3 kg after 12-week period in obese women [ 41]. Don't take this product if you are allergic to sulphur-containing products (such as sulfites) or any of the ingredients listed. If you experience any allergic symptoms, such as skin rashes or difficulty in breathing or any other side effects, please consult your doctor immediately. Hunger Buddy must be taken as a whole capsule with a full glass of water (approximately 250ml). Do not open the capsule and avoid taking it in powder form to avoid choking. There were statistically significant differences in reduction of body fat mass between the study groups at the end of the study (IQP-AE-103 high dose, vs. placebo; low dose, vs. placebo and high dose vs. low dose, ). Reduction of fat-free mass was observed over time in all the three study groups; however, there were no significant differences between the study groups.

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Our findings stand in line with results obtained by Wang et al., who demonstrated that okra intake decreased serum and hepatic total cholesterol and triglyceride levels, and enhanced fecal excretion of bile acids in mice [ 46]. In other study, Kahlon et al. showed that okra polysaccharides have strong bile acid binding properties [ 47]. Furthermore, Chen et al. reported that okra powder showed oil-binding capacities and cholesterol adsorption properties [ 48]. Additionally, results from animal study by Han et al. imply that inulin may also possess a fat-binding property besides its known beneficial effect as prebiotic, which contributed to a lower triglyceride and cholesterol levels in rats fed with high fat diet in the experiments [ 49]. Thus, the cholesterol-lowering effect of IQP-AE-103 could possibly be related to the physicochemical properties of both okra and inulin. At the end of the study, 97.1% of the subjects in the high-dose IQP-AE-103 group and 85.3% in the low-dose group rated the benefits of the treatment as “good” or “very good” compared with 10% in the placebo group. However, investigator rated the benefit as “good” or “very good” for 94.1% and 85.3% of the subjects in high- and low-dose IQP-AE-103 groups, respectively, compared with 6.7% for placebo subjects. In our study, BMI, body fat mass, and waist and hip circumference were also found to be decreased significantly in both IQP-AE-103 dose groups. Lowering waist circumference, a marker of abdominal fat content, indicates that the treatment with IQP-AE-103 could potentially lower the risk of diabetes, coronary heart disease, and nonalcoholic fatty liver disease [ 42– 44]. Additionally, the changes in fat-free mass were not significantly different between the treatment groups, indicating that the weight loss effect was primarily due to body fat reduction.

In summary, the study results provide the first promising evidence that the intake of IQP-AE-103 causes weight loss in overweight and moderately obese subjects in conjunction with a mild hypocaloric diet. The 12-week treatment with IQP-AE-103 also showed very good tolerability. Taken together, IQP-AE-103 can be considered as a safe and effective strategy in fighting obesity with potential benefits in maintaining healthy blood lipids. Data AvailabilityWeight management treatments range from natural, oral solutions to risky, invasive surgical procedures. In the dietary supplement industry, new products constantly offer promises to dieters; yet, most are born from similar technology and mechanisms of action. Furthermore, no change in physical activity was noted by analyzing data from IPAQ-SF. Mean stool frequency did not change significantly in any of the study arms throughout the study. In addition, a combination of dehydrated okra pod powder and inulin, the active ingredients in IQP-AE-103, has been shown to be a strong fat-binding agent in an in vitro setting simulating in vivo conditions (data not shown); it also exerts high swelling capacity and significantly enhances solution viscosity. Thus, IQP-AE-103 appears to be a promising natural agent that may help to control calorie intake, decrease absorption of dietary fat, and consequently lead to body weight reduction.