The onset of labour may be delayed, and duration increased with an increased bleeding tendency in both mother and child (see section 4. g, pruritus, urticaria, angioedema and, more rarely, exfoliative and bullous dermatoses (including epidermal necrolysis, and erythema multiforme). reduction in blood cells (causing sore throat, mouth ulcers, flu-like symptoms, severe exhaustion, unexplained bleeding, bruising and nosebleeds. This would result in the patient taking 400mg/day more of ibuprofen than currently authorised as P or GSL, resulting in a total ibuprofen daily intake of 1600mg. This product is formulated using a technology which releases both Ibuprofen and Paracetamol simultaneously, so that the active ingredients deliver a combination effect.

Have or have had asthma, diabetes, high cholesterol, high/low blood pressure, a stroke, heart, liver, kidney or bowel problems. studies suggest that use of ibuprofen, particularly at high doses (2400 mg/day) may be associated with a small increased of arterial thrombotic events (for example myocardial infarction or stroke) (see section 4. The clinical efficacy of ibuprofen and paracetamol has been demonstrated in pain associated with headache, toothache and dysmenorrhoea, and fever, furthermore efficacy has been shown in patients with pain and fever associated with cold and influenza and in pain models such as sore throat, muscular pain or soft tissue injury and backache. As the pack size is limited to 16 tablets, treatment is limited to 3 days, and the label and leaflet clearly state the dose, it is considered that the risk of overdose is minimised acceptably. NSAIDs should not be used during the first two trimesters of pregnancy or labour unless the potential benefit to the patient outweighs the potential risk to the foetus.

Nuromol has a reduced dosage of paracetamol compared to solid dose oral paracetamol products that are already authorised with GSL classification and there is a lower rate of reported adverse events with the combination compared with the individual actives alone. If vomiting is not a problem, oral methionine may be a suitable alternative for remote areas, outside hospital. Nuromol Dual Action starts working faster than Ibuprofen and last longer than Paracetamol alone providing up to 9 hours of pain relief.

In one study, when a single dose of ibuprofen 400mg was taken within 8 h before or within 30 min after immediate release acetylsalicylic acid (81mg), a decreased effect of acetylsalicylic acid on the formation of thromboxane or platelet aggregation occurred. Antenatal monitoring for oligohydramnios and ductus arteriosus constriction should be considered after exposure to Ibuprofen for several days from gestational week 20 onward.NSAIDS should be given with care to patients with a history of gastrointestinal disease (ulcerative colitis, Crohn's disease) as these conditions may be exacerbated (see section 4. g. misoprostol or proton pump inhibitors) should be considered for these patients, and also for patients requiring concomitant low dose acetylsalicylic acid, or other drugs likely to increase gastrointestinal risk (see below and 4. The risk of GI bleeding, ulceration or perforation is higher with increasing NSAID doses, in patients with a history of ulcer, particularly if complicated with haemorrhage or perforation (see Section 4.

Management should be symptomatic and supportive and include the maintenance of a clear airway and monitoring of cardiac and vital signs until stable. The patient should consult a doctor if the symptoms persist or worsen or if the product is required for more than 3 days.

This product has a fast onset of action with 'confirmed perceptible pain relief' achieved in a median of 15. If you are pregnant, think you are pregnant, or breastfeeding speak with your doctor or our pharmacist here before taking this medication. Product images: whilst we try to keep out product images up to date we may, particularly for non-branded products ship the same medicine but in different packaging. This means that the sub-licensee must not use IHTSDO SNOMED CT Browser to add or copy SNOMED CT identifiers into any type of record system, database or document.