Special precautions to be taken by the person administering the veterinary medicinal product to animals In the interests of good hygiene, persons administering the tablet directly to a dog or by adding it to the dog's food, should wash their hands afterwards.

The rest of this leaflet discusses the medicines that may be used to treat worm infections. See the separate leaflets called Roundworms, Threadworms and Schistosomiasis. Anthelmin Plus Flavour – For treatment of dogs administer 1 tablet per 10kg bodyweight (15 mg/kg bodyweight febantel, 14.4 mg/kg pyrantel and 5 mg/kg praziquantel). This is equivalent to 1 tablet per 10 kg bodyweight. Tablets may be halved/quartered to allow accuracy of dosing. Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via: ADRs identified from clinical trials and post-marketing experience with Anthelmin are included in Table 1. The displayed frequency categories use the following convention:Most worm infections occur in warm tropical countries or developing countries where food and water may not be clean. It is thought that millions of people around the world are infected with worms at any one time. Very common (>1/10); Common (>1/100 to <1/10); Uncommon (>1/1000 to <1/100); Rare (>1/10,000 to <1/1000); Very rare (<1/10,000), Not known (cannot be estimated from the available data). Roundworms - the most common roundworm infections are thought to be caused by threadworms, ascaris, hookworms and trichuris. Roundworm eggs usually enter the body by the person eating food or drinking water that contains eggs. The eggs live and hatch in the gut (intestine). particular Taenia spp. and Dipylidium caninum .Praziquantel acts against adult and immature forms of

Table 1: Adverse Drug Reactions Reported in Clinical Trials and Post-marketing Experience for Anthelmin Do not use the product in the first two thirds of pregnancy. The product may be used during lactation. particular, the activity spectrum covers Toxocara canis , Toxascaris leonina , Uncinaria stenocephala and AncylostomaOrally administered mebendazole is extensively metabolised primarily by the liver. Plasma concentrations of its major metabolites (amino and hydroxylated amino forms of mebendazole) are substantially higher than those of mebendazole. Impaired hepatic function, impaired metabolism, or impaired biliary elimination may lead to higher plasma levels of mebendazole. crush it in their food. If your vet says the tablet can be crushed up and given with food, try crushing it up and mixing it with one of their daily meals (ideally breakfast depending on the time you need to give them their tablet). Make sure they eat all their meal, though, otherwise they may miss some of their medication. Or you could try mixing it, unless your cat is sensitive to the ingredients, in a soft yoghurt-textured treat for cats

Anthelmin Plus Flavour– For treatment of dogs administer 1 tablet per 10kg bodyweight (15 mg/kg bodyweight febantel, 14.4 mg/kg pyrantel and 5 mg/kg praziquantel). This is equivalent to 1 tablet per 10 kg bodyweight. Tablets may be halved/quartered to allow accuracy of dosing.

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Flukeworms - these worms can live in the blood vessels, gut, lungs or liver. You usually become infected with flukeworms by swimming or washing in fresh water that contains flukeworms. An infection with flukeworms causes a tropical disease called schistosomiasis. Mebendazole, the conjugated forms of mebendazole, and its metabolites likely undergo some degree of enterohepatic recirculation and are excreted in the urine and bile. The apparent elimination half-life after an oral dose ranges from 3 to 6 hours in most patients. Following oral administration, < 10% of the dose reaches the systemic circulation, due to incomplete absorption and to extensive pre-systemic metabolism (first-pass effect). Maximum plasma concentrations are generally seen 2 to 4 hours after administration. Dosing with a high fat meal leads to a modest increase in the bioavailability of mebendazole.