The product is available without prescription and applies easily with a no-mess, silicone tip applicator. Adverse events (AEs) occurring between administration of the first dose of Kerasal Nail and the end of the 4-week treatment period were recorded. My podiatrist said there was no way to kill toenail fungus other than permanently removing the nail, which is what she recommended. In one early study, a different test solution containing these same three ingredients cured or yielded improvements in 21 of 23 patients with culture-positive onychomycosis when used for 2 to 6 months [11] .

The final study protocol (dated 20 Oct 2015) and the patient information and consent form (version 1. Apply a thin layer 2 times per day for the first week of use, once in the morning and once at night directly to affected nail and under the free edge of the nail (toe or finger nails). In the present study, patient-rated improvements in affected nails were achieved with few treatment-related AEs. After 1, 2 and 4 weeks of treatment, they assessed the appearance of the target nail on a 4-point scale, with a score of ≥2 indicating a minimum of some improvement. Among the fungal patch brew are those well-known table staples, aluminum glycinate and polysorbate 80.After the first week of treatment, the attribute that was improved in the highest proportion of patients was discoloration (55. This Kerasal Nail 10ml Fungal Renewal Treatment offers a three-month supply of an effective remedy for nail fungus. In summary, Kerasal Nail produced very rapid improvements in nail appearance in patients with onychomycosis and was well tolerated.

A subsequent 24-week randomized double-blind placebo-controlled study in 493 patients with distal subungual onychomycosis investigated K101, which is similar to Kerasal Nail but has a higher urea content (20% vs 9. Eight patients were excluded from the PPS because of inadequate treatment compliance (n = 1) or major protocol deviations (n = 7). This in turn may prevent local irritation and pain such as that seen in 6% of participants in the 24-week study of K101 [12] , in which K101 was applied dropwise. Execution of the study, data analysis and reporting were outsourced to a contract resource organization.

As outlined above, treatments containing propylene glycol, urea, and lactic acid have shown good efficacy and tolerability in clinical investigations. I thought it would go away, but I felt like the discoloration was expanding and the shape of fingernail distorted. of patients (95/103) reported at least some visible improvement in the target nail (95% confidence interval [CI] 87. The excellent safety profiles of K101-03 and similar products are in marked contrast to the potential toxicity associated with systemic antifungal treatments for onychomycosis [ 5]. would be sufficient to confirm early visible improvements in target nail appearance (success being defined as a score of ≥2 on the 4-point global assessment scale after 4 weeks of treatment).

The present study indicates that K101-03 rapidly improves the nails of patients with onychomycosis and/or nail psoriasis. More- over, the patient sample in the present study covered both sexes and a wide age range (26 to 86 years). Kerasal Nail has a unique rapid mechanism of action and has demonstrated strong competitive results, including visible improvements already within 2-4 weeks. The 103 third parties who use cookies on this service do so for their purposes of displaying and measuring personalized ads, generating audience insights, and developing and improving products. To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average.

As you use it over time and your nail becomes softer, you can start to file down the tops to thin it out as you continue treatment.

FINALLY I feel like I’m not getting the run around and won’t be wasting my money on a bogus “treatment”. Nick Choi, clinical trial coordinator at the Division of Dermatology, National University Hospital, Singapore. I’m into my second week of using this product and it has taken the yellow out of my effected toe nail. Zeichner recommends reaching for Vaseline, since it forms a protective seal to help hydrate and soften the nail and underlying skin.After 4 weeks of treatment, discoloration, thickening, brittleness and softness were each improved in more than half of patients. They began to see improvement after a couple of days of using Kerasal, and within two weeks, the "nails on one foot are now 90%+ normal in appearance [and] on the other foot [they are] 60%+ normal in appearance. While not dangerous per se, it often causes pain and discomfort and can worsen health-related quality of life, particularly in patients with persistent symptoms [5] . Approximately half of the patients reported a clear or very good visible improvement in the target nail after 4 weeks of K101-03 treatment (Table ​ (Table3 3). I still have toenail fungus under the main part of the nail, but the pain is gone from the big toe because the nail is in better shape.