Siegel D, Devaraj S, Mitra A, Raychaudhuri SP, Raychaudhuri SK, Jialal I. Inflammation, atherosclerosis, and psoriasis. Clin Rev Allergy Immunol. 2013; 44:194–204. doi: 10.1007/s12016-012-8308-0. [ PubMed] [ CrossRef] [ Google Scholar] CoQ10 is also effective in reducing the pain associated with angina, which is chest pain caused by your heart muscle not getting enough oxygen ( 16).

Di Lorenzo A, et al. (2020). Clinical evidence for Q10 Coenzyme supplementation in heart failure: From energetics to functional improvement. Nerve pain in people with diabetes ( diabetic neuropathy). Research shows that taking coenzyme Q10 improves nerve damage and nerve pain in people with nerve damage caused by diabetes. Qu H, Guo M, Chai H, et al. Effects of coenzyme q10 on statin‐induced myopathy: an updated meta‐analysis of randomized controlled trials. J Am Heart Assoc. 2018;7(19):e009835. doi:10.1161/JAHA.118.009835

We have one of the strongest concentrations in the UK at exceptional value. The technical name for Coenzyme Q10 is Ubiquinone. It is a nutrient found in every cell of the body and is widely known as the body’s spark plug. CoQ10 occurs naturally in the human body, most abundantly in the heart. It is anantioxidant nutrient and it plays an essential role in helping to release energy from the food we consume. Emami A & Bazargani-Gilani B. (2018). Effect of oral CoQ 10 supplementation along with precooling strategy on cellular response to oxidative stress in elite swimmers. Wu Y, et al. (2019). Mitochondrial dysfunction in neurodegenerative diseases and drug targets via apoptotic signaling. Derosa, G., et al. (2019). Coenzyme Q10 liquid supplementation in dyslipidemic subjects with statin-related clinical symptoms: A double-blind, randomized, placebo-controlled study.

A review of 13 studies in people with heart failure found that 100 mg of CoQ10 per day for 12 weeks improved blood flow from the heart ( 14). Shidal C, et al. (2019). Prospective study of plasma levels of coenzyme Q10 and lung cancer risk in a low-income population in the Southeastern United States. Schmelzer C, Lindner I, Rimbach G, Niklowitz P, Menke T, Doring F. Functions of coenzyme Q10 in inflammation and gene expression. Biofactors. 2008; 32:179–183. doi: 10.1002/biof.5520320121. [ PubMed] [ CrossRef] [ Google Scholar] Manzar H, et al. (2020). Cellular consequences of Coenzyme Q10 deficiency in neurodegeneration of the retina and brain.Both oxidative stress and mitochondrial dysfunction have been linked to the onset and progression of diabetes and diabetes-related complications ( 25). Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? For example, oxidative stress can cause damage to sperm DNA, potentially resulting in male infertility or recurrent pregnancy loss ( 31).

Molyneux SL, Young JM, Florkowski CM, Lever M, Georgr PM. Coenzyme Q10: is there a clinical role and a case for measurement? Clin Biochem Rev. 2008; 29:71–82. [ PMC free article] [ PubMed] [ Google Scholar] Beaulieu S, Vachon A, Plourde M. Women have higher levels of CoQ10 than men when supplemented with a single dose of CoQ10 with monoglycerides omega-3 or rice oil and followed for 48 h: a crossover randomised triple blind controlled study. J Nutr Sci. 2022;11:e2. doi:10.1017/jns.2021.106 Coenzyme Q10. Natural Medicines. https://naturalmedicines.therapeuticresearch.com. Accessed Oct. 18, 2020. Further large-scale RCTs are necessary to determine whether CoQ10 is a viable treatment for people experiencing statin-related muscle pain. Treating migraines

Similarly, these supplements may improve female fertility by stimulating ovarian response and help slow ovarian aging ( 33). Coenzyme Q10 (PDQ)-Health Professional Version. National Cancer Institute. https://www.cancer.gov/about-cancer/treatment/cam/patient/coenzyme-q10-pdq#section/all. Accessed Oct. 18, 2020. Coenzyme Q10 has also been used to treat Alzheimer's disease, high cholesterol, or amyotrophic lateral sclerosis ( Lou Gehrig's disease). However, research has shown that this medicine may not be effective in treating these conditions.