Please refer to the NHSGGC Central Prescribing Memorandum on StaffNet for advice to support the management of affected patients. High doses of acetylsalicylic acid may result in closure of foetal ductus arteriosus in utero and possibly persistent pulmonary hypertension in the new born. Kernicterus may be a consequence of jaundice in neonates.

Make sure you follow the dosage instructions and do not take more than the stated dose. 4. POSSIBLE SIDE EFFECTS Colestipol (Colestid®) orange and plain 5g granule sachets – both preparations have been discontinued. Other bile-acid sequestrants remain available and can support the uplift in demand. You should ask your doctor before taking aspirin if you are taking any other medicines including those for blood clots (thrombosis) such as warfarin or gout such as probenecid. Salicylate poisoning is usually associated with plasma concentrations >350 mg/L (2.5 mmol/L). Most adult deaths occur in patients whose concentrations exceed 700 mg/L (5.1 mmol/L). Single doses less than 100 mg/kg are unlikely to cause serious poisoning. FDA is alerting consumers of a voluntary recall of Bayer’s Alka-Seltzer Plus products due to labeling errors.Do not take Alka-Seltzer XS if you are pregnant, breast-feeding or trying for a baby unless directed byyour doctor. Aspirin can prolong labour and affectblood clotting in the mother or baby. Were sold only in the U.S. at Walmart, CVS, Walgreens and Kroger (including Dillons Food Stores, Fred Meyer, Fry's Food Stores, Ralphs, King Soopers and Smith's Food and Drug) after February 9, 2018. Although clinical and epidemiological evidence suggests the safety of acetylsalicylic acid for use in pregnancy, caution should be exercised when administered to pregnant patients.

The speed of absorption of paracetamol may be increased by metoclopramide or domperidone and absorption reduced by cholestyramine. The intake of acetylsalicylic acid by breast-feeding patients should be avoided as there is a risk of Reye's syndrome. Regular use of high doses could impair platelet function and produce hypoprothrombinaemia in the infant if neonatal vitamin K stores are low. Consumers may also report adverse reactions or quality problems experienced with the use of this product to the FDA’s MedWatch Adverse Event Reporting program either online, by regular mail or by fax.

Pharmacy product

Are about to have surgery. Before the operationtell the doctor or surgeon that you are takingaspirin. Immediate medical advice should be sought in the event of an overdose, even if you feel well, because ofthe risk of delayed, serious liver damage. Are allergic to any other pain relieving oranti-inflammatory medicines (eg NSAIDS orsalicylates). For more information see section 4‘Possible Side Effects’. Do not take Alka-Seltzer XS for more than 3 days in a row. If symptoms persist, speak to your doctor orpharmacist.