Briggs, W. H., Folts, J. D., Osman, H. E., and Goldman, I. L. Administration of raw onion inhibits platelet-mediated thrombosis in dogs. J.Nutr. 2001;131(10):2619-2622. View abstract. Group 2 (diabetic group) had a significant increase in FBW, BWG and FER compared to the normal rat's group 1 (natural control group) by 251.66 g, 119.15 g and 0.232%, respectively. Rimm EB, Katan MB, Ascherio A, et al. Relation between intake of flavonoids and risk for coronary heart disease in male health professionals. Ann Intern Med 1996; 125:384-9.

Onion (Allium cepa L.) peels: A review on bioactive (PDF) Onion (Allium cepa L.) peels: A review on bioactive

Results also indicated the appearance of tow peaks one was located at almost the same temperature between 66.13 and 79.24°C which was attributed to the un-sheathed red onion peel extract remaining after the nano-emulsion process. Results showed that the G 2 had a significant increase in blood glucose level compared to G 1 by 231.58 mg dL –1. Rats were fed on ROPEE, ROPEMCs and ROPENEs in a separate way in groups showed that G 3, G 4 and G 5 significantly decreased blood glucose level when compared to G 2, the decreases in blood glucose level in G 3 fed a sponge cake containing ROPEE after 30, 60, 120 and 240 min from taking a glucose dose were 205.37, 178.64, 166.82 and 152.95 mg dL –1, respectively. Determination of total phenolics and flavonoids contents of rope forms: Total phenolics contents were determined by using Folin-Ciocalteu assay 20. The ROPE forms samples (1 mg mL –1) were dissolved separately in 1.0 mL methanol and then mixed with 2 mL of 2% aqueous sodium carbonate solution. After 3 min, 100 μL of 50% Folin-Ciocalteu’s reagent was added to the mixture. After 30 min of standing, the absorbance was measured at 750 nm with a spectrophotometer (2120 UV, Optizen, Daejeon, Korea). The results were derived from a calibration curve (y = 9.57x−0.14, R 2 = 0.995) of gallic acid (0-250 μg mL –1) and expressed in Gallic Acid Equivalents (GAE) per gram extract weight.Dorsch, W., Ettl, M., Hein, G., Scheftner, P., Weber, J., Bayer, T., and Wagner, H. Antiasthmatic effects of onions. Inhibition of platelet-activating factor-induced bronchial obstruction by onion oils. Int.Arch.Allergy Appl.Immunol. 1987;82(3-4):535-536. View abstract.

Onion Extract Vegetable Capsules Quercetin Antioxidant Allium Onion Extract Vegetable Capsules Quercetin Antioxidant Allium

Hong, Y. J. and Mitchell, A. E. Metabolic profiling of flavonol metabolites in human urine by liquid chromatography and tandem mass spectrometry. J Agric.Food Chem. 11-3-2004;52(22):6794-6801. View abstract. Whereas, the decrease in the blood sugar level of rats in groups 4 and 5 was lower as a result of coating the red onion peel extract with a layer of sodium alginate, either in the form of nano-emulsions or in the form of micro-capsules as they protect them from any changes in anti-oxidant properties and consequently spread their ability to reduce blood sugar in mice with diabetes. Results showed that G 4 which is fed on sponge cake contains ROPEMCs decreased by 162.52, 146.08, 128.53 and 91.33 mg dL –1 after 30, 60, 120 and 240 min from taking a glucose dose. While there was more reduction in blood glucose observed in G 5 fed on sponge cake contains ROPENEs after 30, 60, 120 and 240 min being 143.18, 135.31, 121.67 and 85.94 mg dL –1, respectively. Application: The effect of adding ROPEE, ROPEMCs and ROPENEs to sponge cake compared to the control sample and their physical properties and sensory evaluation are shown in Table 6 and 7, respectively.

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Kook, S., Kim, G. H., and Choi, K. The antidiabetic effect of onion and garlic in experimental diabetic rats: meta-analysis. J Med Food 2009;12(3):552-560. View abstract. Dpph radical scavenging activity: Antioxidant activity based on the results of DPPH free radical scavenging activity in Table 5, all 2 red onion peel extracts (ROPEE and ROPWE) acted as an antioxidant by donating their electron to scavenge radicals rather than inhabitation the formation of lipid peroxide during oxidation. The antioxidant activity of ROPEE and ROPWE extracts was 89.21 and 43.87%, respectively and the highest DPPH radical scavenging was observed in ROPEE. Table 3: Extraction yield, total phenolic content of ROPE, ROPEMC and ROPENE coated with chitosan, sodium alginate and gelatin The results showed that the ethanol extracts high content of bioactive compounds compared to water extract and that the use of nano-technique as a new emerging technology in form of nano-emulsion using sodium alginate with diameter size between 8.3-13.6 nm. Results also indicated that there was an improvement in the efficiency of antioxidant activity at high-temperature degrees during baking, with a melting point of up to 223.64°C, with an improvement in the blood sugar levels of diabetic rats and a significant decrease in body weight. Herman-Antosiewicz, A. and Singh, S. V. Signal transduction pathways leading to cell cycle arrest and apoptosis induction in cancer cells by Allium vegetable-derived organosulfur compounds: a review. Mutat.Res. 11-2-2004;555(1-2):121-131. View abstract.