Hypersensitivity, angioedema, urticaria, ulcerative stomatitis, angioneurotic oedema and very rare anaphylactic reactions.

Once you have stopped smoking, taking exercise regularly will not only help you get fitter but will encourage you to relax. Exercise has the ability to relieve stress and tension. Taken regularly it will benefit you physically and psychologically. self-help tips to stop smoking. NHS England. https://www.nhs.uk/live-well/quit-smoking/10-self-help-tips-to-stop-smoking/ . Accessed 26/6/23. You may have tried to stop smoking before and you know from bitter experience that it’s not easy to give up cigarettes. Which strength: If you smoke less than 20 cigarettes per day, consider Nicotinell 2 mg medicated gum; smokers of more than 20 cigarettes per day should consider Nicotinell 4 mg medicated gum One of the really noticeable benefits of ‘stopping’ is the extra cash that’s suddenly available. To emphasise the point put the money into a pot marked ‘cash not ash’ and watch it accumulate. But be sure to use the money to treat yourself. You deserve a reward for not smoking.Piper ME, Smith SS, Schlam TR, Fiore MC, Jorenby DE, Fraser D, et al. A randomized placebo-controlled clinical trial of 5 smoking cessation pharmacotherapies. Arch Gen Psychiatry. 2009 Nov;66(11):1253-62. Contraindications: Known hypersensitivity to nicotine or any of the excipients. Use by non-smokers. Patch and gum: use by occasional smokers. Patch: diseases of the skin. This adverse event could be due to mechanical stress caused by chewing of the gum rather than due to the direct action of nicotine.

Nicotinell gums can cause adverse reactions similar to those associated with nicotine administered by other means (including smoking) These can be attributed to the pharmacological effects of nicotine, which are dose dependant. Non dose-dependent adverse reactions are as follows: Why Nicotinell:Nicotinell nicotine gum helps to quit smoking by relieving five withdrawal symptoms of quitting - anxiety, frustration, restlessness, irritability and cravings Nicotinell Gum 2mg is particularly useful forlight smokers who are more likely to experience less severe withdrawal symptoms, and for those who have previously failed to stop smoking with nicotine replacement therapy. Individuals with a tendency to experience indigestion may suffer initially from minor degrees of indigestion or heartburn if the 4 mg dose is used - slower chewing in the case of gum or the use of the 2 mg dose (if necessary more frequently) will usually overcome this problem.

About Nicotinell Gum

Nicotinell chewing gum provides on-the-go relief when the urge to smoke strikes and helps relieve 5 withdrawal symptoms of quitting such as anxiety, frustration, restlessness, irritability, and cravings. Hughes JR. Effects of abstinence from tobacco: valid symptoms and time course. Nicotine Tob Res. 2007;9(3):315-327. Maintain a clear airway/ensure adequate ventilation. Monitor pulse and BP. Perform 12 lead ECG and measure QRS duration and QT interval and repeat especially if the patient is symptomatic or has taken slow release preparations Polycyclic aromatic hydrocarbons in tobacco smoke induce the metabolism of drugs catalysed by CYP 1A2 (and possibly CYP 1A1). When a smoker stops, this may result in slower metabolism and a consequential rise in blood levels of drugs such as theophylline, tacrine, olanzaprine and clozaprine.

Overdose with Nicotinell gum may only occur if many pieces are chewed simultaneously. Nicotine toxicity after ingestion will most likely be minimized as a result of early nausea and vomiting that occur following excessive nicotine exposure. Risk of poisoning by swallowing the gum is small. Since the release of nicotine from the gum is slow, very little nicotine is absorbed from the stomach and intestine, and if any is, it will be inactivated in the liver. Doses of nicotine tolerated by adult and adolescent smokers can produce severe toxicity in small children that may be fatal (please see section 4.9). Products containing nicotine should not be left where they may be misused, handled or ingested by children. Nicotinell gum should be disposed of with care. Nicotine products should be kept out of sight and reach of children. Quitting with a fellow smoker is a good idea. It will strengthen your resolve and build on your determination. Nicotinell 2mg gum contains less than 1 mmol sodium (23 mg) per chewing gum, that is to say essentially 'sodium-free'. Gum range: Nicotinell nicotine gum are a stop smoking aid available 2 mg and 4 mg strengths in three sugar free flavours - mint, fruit and liquoriceLow (2 mg gum) or high (4 mg gum) dose forms are acceptable depending on patient characteristics and preference. Jaw muscle ache, erythema, urticaria, hypersensitivity, angioneurotic oedema and anaphylactic reactions. Good neurological outcome after cardiac arrest (due to nicotine poisoning) may occur after prolonged resuscitation. Cardiac arrest in hospital or witnessed out of hospital, with bystander CPR, should be continued for at least 1 hour (discuss with local poisons centre) Treatment of overdose should be immediate as symptoms may develop rapidly (particularly in children). All nicotine intake should stop immediately. Emesis is usually spontaneous.

One of the really noticeable benefits of ‘stopping’ is the extra cash that’s suddenly available. To emphasise the point put the money into a pot marked ‘cash not ash’ and watch it accumulate. But be sure to use the money to treat yourself. You deserve a reward for not smoking. Dealing with relapses As you chew, the gum releases nicotine to help ease your physical cravings and reduce your desire to smoke. To get maximum effectiveness from Nicotinell Gum, it's critical you follow a 'chew and park' method for at least 30 minutes. Chewing the gum for a couple of minutes only without parking it, doesn't allow the gum to help provide relief from cravings. Continue using the same number of pieces of gum or lozenge and reduce to the Step 2 patch for 3-4 weeks. Then use the Step 3 patch for 3-4 weeks. When the patch is no longer needed gradually reduce the number of pieces of gum or lozenge until you no longer need them.Even small quantities of nicotine are dangerous in children, and may result in severe symptoms of poisoning which may prove fatal. If poisoning is suspected in a child, a doctor must be consulted immediately. Giving up is more difficult for some people than others. If you fail to stop first time, don’t be disheartened. Try again at a later date – you can do it! Precautions: Use with caution in patients with: recent myocardial infarction, unstable or worsening angina including Prinzmetal's angina, severe cardiac arrhythmias, uncontrolled hypertension, or recent cerebrovascular accident who are considered to be haemodynamically unstable, history of epilepsy or those taking anti-convulsant therapy, diabetes mellitus, hyperthyroidism, pheochromocytoma, moderate to severe renal and/or hepatic impairment, active oesophagitis, oral and pharyngeal inflammation, gastritis, gastric/peptic ulcer. Gum: Not recommended for those with jawbone joint problems or denture wearers. May loosen fillings or dental implants. Do not use in patients with hereditary conditions of fructose intolerance. Contains butylhydroxytoluene which may cause irritation to the mucous. Patch: Have a history of dermatitis. Discontinue use if a severe or persistent skin reaction, including allergic reaction, occurs. Nicotinell TTS contains aluminium and should be removed prior to undergoing defibrillation, MRI or cardioversion procedures. Lozenge: Use with caution in patients with: hypertension, stable angina pectoris, cerebrovascular disease, occlusive peripheral arterial disease and heart failure. Contain aspartame, may be harmful to those with phenylketonuria. Do not use in patients with hereditary conditions of fructose intolerance. Children or adults who have accidentally ingested less than 0.2 mg/kg nicotine and who have no new symptoms since the time of ingestion do not need to be referred for medical assessment. Patients should be advised to seek medical attention if symptoms develop.