Chandran N, Goyal V, Moriarty R, Ostrovsky R (2014) Position-based cryptography. SIAM J Comput 43(4):1291–1341. https://doi.org/10.1137/100805005 Gallbladder carcinoma (GBC), with adenocarcinoma as the most common histological type, is a relatively rare but stubborn and deadly malignancy worldwide 1. It commonly develops from gallstones, pancreaticobiliary maljunction (PBM), or seldom gallbladder polyps, usually accompanied by persistent inflammation 2. GBC carcinogenesis is conceivably concerned by 10%–20% of adults affected by gallstones in the global populations 3. Nevertheless, unlike gastrointestinal cancers, our understanding of GBC is impeded by the disease rarity and difficulty in acquiring fresh samples, given that biopsy is not always feasible and surgically resected tissues are frequently dedicated to fresh-frozen sections 2. In a compromise, as one specific subtype, GBC has long been fathomed in a heterogeneous collection of biliary tract cancers across epidemiological, genomic, and clinical studies. In fact, despite resembling other biliary tract cancers in epithelial immunological response or cellular origin, GBC exhibits distinct mucosal structure (e.g., absence of peribiliary glands), physiological function (e.g., vivid fluid transport), and local milieu (e.g., a higher concentration of bile salts), which presumably lead to genomic, transcriptomic, as well as clinical disparities. N00.00200: Domain Morphology and Rheological Properties of Protein-Polyelectrolyte Complex Hydrogels N00.00015: Elucidating the Roles of Grafting Density and Bonding Types on the Tethered Polymer Dynamics in Nanoparticle Organic Hybrid Material System We further investigated the interplay between fibroblasts and mEPCs by cell–cell communication analysis. ERF principally interacted with mEPCs via collagen family members and collagen receptor integrins α1β1/α2β1 (Supplementary Fig. S14). In contrast, IRF actively communicated with mEPCs through HLA-C, perhaps implying their capacity in antigen presentation (Supplementary Fig. S15). Besides, MIF-EGFR/TNFRSF14, IGF1/2-IGF1R/2 R, TNFSF12-TNFRSF12A (TWEAK-Fn14) interactions also mediated the crosstalk between TPF or SLF with EPCs, consistent with their function in facilitating tumor progression (Supplementary Figs. S16, S17 and Table S6).

APS -APS March Meeting 2023 - Session Index MAR23

N00.00316: In-silico investigation into nanoparticle formation, selective active compound delivery into cancer cells and transcytosis across the blood-brain barrier This study deciphered components and phenotypes across cholecystitis and GBC ecosystems by scRNA-seq analysis of 140,870 cells (Fig. 8f). We identified three subtypes of cancer cells closely linked to TME cellular predilection as well as patient prognosis. We also dissected potential interactions between cancer cells and TME cells. This comprehensive single-cell transcriptome atlas provides a valuable resource for understanding mechanisms underlying the malignant transformation of chronic cholecystitis and GBC progression, further paving ways for developing precision therapies for GBC. To ensure each cell paired with a bead in a Gel Beads-in emulsion (GEM), 10× library preparation and sequencing beads with the unique molecular identifier (UMI) and cell barcodes were loaded close to saturation. Polyadenylated RNA molecules hybridized to the beads after exposure to the cell lysis buffer. Beads were retrieved into a single tube for reverse transcription. On cDNA synthesis, each cDNA molecule was tagged on the 5’ end with UMI and cell label indicating its cell of origin. Briefly, 10× beads were then subject to second-strand cDNA synthesis, adaptor ligation, and universal amplification. Sequencing libraries were prepared using randomly interrupted whole-transcriptome amplification products to enrich the 3’ end of the transcripts linked with the cell barcode and UMI. All the remaining procedures including the library construction were performed according to the standard manufacturer’s protocol (CG000206 RevD). Sequencing libraries were quantified using a High Sensitivity DNA Chip (Agilent) on a Bioanalyzer 2100 and the Qubit High Sensitivity DNA Assay (ThermoFisher). The libraries were sequenced on NovaSeq6000 (Illumina) using 2 × 150 chemistry (Shanghai Bohao Biotechnology; Shanghai OEbiotech Corporation). DNA isolation and whole exon sequencing (WES) Bunin, A. et al. Protein tyrosine phosphatase PTPRS is an inhibitory receptor on human and murine plasmacytoid dendritic cells. Immunity 43, 277–288 (2015).

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N00.00382: Dynamical thermal activated effects of vacancy molecular and atomic gas adsorption in graphene Amod U Madurapperumage, Jailyn Johnson, Manjula P Senanayake, Shalika D Meedin, Gary S Grest, Dvora Perahia

Journal of Petroleum Science and Engineering - ScienceDirect

N00.00060: Freeze-tolerant and high-stretchable lithium acrylate-based hydrogel polymer electrolyte for superior hybrid supercapacitors N00.00063: Effect of chemical defects on enhanced piezoelectric property of poly(vinylidene fluoride) by high-power ultrasonication Daniela M Rivera Mirabal, Shawn Mengel, Audra J DeStefano, Kai-Chieh Yang, Songi Han, Scott Shell, Rachel A Segalman N00.00042: Formation of Mesoglobules and Phase Separation at Variable Pressure in Aqueous Poly(N-isopropylacrylamide) Solutions Probed with Very Small-Angle Neutron ScatteringN00.00062: Electrospun polyampholyte nanofibers with different hydrophobic and ionic chain densities N00.00027: Compatibilization of a Crystalline Polymer Blend by Molecular Design and Control of Crystallization Xuanye Leng, Samantha R McCuskey, Glenn Quek, Ricardo Vazquez, Yude Su, Mariana Costa, Siyu Chen, Musen Chen, Kou Yang, Jinpei Zhao, Mo Lin, Zhaolong Chen, Guillermo Bazan, Konstantin Novoselov, Daria V Andreeva

Erdong Wang (0000-0001-8233-4941) - ORCID

N00.00372: An Ab-initio Perspective on Simultaneous Detection of Uric Acid and Ascorbic Acid Using Graphene Oxide N00.00390: Synthesis of nanometric crystals of sodium and calcium zirconates as solid heterogeneous catalyst for biodiesel production. Cytotoxicity and exhaustion signatures were derived from differentially expressed genes across all CD8 + T cell subtypes. Pearson correlation between the reference gene GZMK (cytotoxicity signature) or HAVCR2 (exhaustion signature) and all other genes across CD8 + T cells using scaled expression values was analyzed. The top 30 genes having the highest correlation with the reference genes ( GZMK or HAVCR2) were defined as cytotoxicity and exhaustion signature genes, respectively. For CD4 + T cells, the IL2RA gene was chosen as the reference gene for defining the Treg signature using the same method. We computed signature scores for individual cells using AddModuleScore function in Seurat. WES analysis

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Amphiphilic Rhamnolipid Molybdenum Disulfide Nanosheets for Amphiphilic Rhamnolipid Molybdenum Disulfide Nanosheets for

N00.00315: 1H and 19F NMR Spectroscopy and DFT calculations to Investigate Tethering of Silver Nanoparticles (AgNPs) with Ofloxacin Antibiotic for Drug Delivery Gerzain Jaimez Layna, CONCEPCION MEJIA GARCIA, Elvia Díaz Valdés, María de Lourdes Rojas Morales, Miguel Avendaño Ibarra, Karla Jenny Lozano Rojas, Ángel Guillen Cervantes Chiang JT, Haas JJ, Hu YC (2009) Secure and precise location verification using distance bounding and simultaneous multilateration. In: WISEC, pp 181–192 Wang E, Ben-Zvi I, Rao T, Dimitrov DA, Chang X, Wu Q, Xin T (2011) Secondary-electron emission from hydrogen-terminated diamond: Experiments and model. Physical Review Special Topics - Accelerators and Beams. doi: 10.1103/physrevstab.14.111301 N00.00320: An emergent property of collective migration: spatial organization of motility phenotypesN00.00029: Limiting Side-Reaction Impact on Recyclability of Diels-Alder Networks Containing Furan-Maleimide Resins Wang E, Rahman O, Skaritka J, et al (2022) High voltage dc gun for high intensity polarized electron source. Physical Review Accelerators and Beams 25:. https://doi.org/10.1103/physrevaccelbeams.25.033401 Luka Pocivavsek, Willa Li, Ziga Donik, Kameel Khabaz, Blessing Nnate, Junsung Kim, David Jiang, Alyssa Varsanik, Kayla Polcari, Nhung Nguyen R Bharath Venkatesh, Jonathan Bingaman, Jung Hyun Ahn, Lynn M Walker, Susannah L Scott, Rachel A Segalman