Nicotinell Lozenge can cause adverse reactions similar to those associated with nicotine administered by smoking. These can be attributed to the pharmacological effects of nicotine, which are dose- dependent. Non dose-dependent adverse reactions are as follows: hypersensitivity, angioneurotic oedema and anaphylactic reactions. Using nicotine replacement therapy in combination with bupropion (Zyban) or varenicline (Champix) is not currently recommended. However, you can use Nicotinell lozenges in combination with other nicotine replacement products such as nicotine patches if you find this is helpful. Ask your pharmacist for advice. What other nicotine replacement therapies are available? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your

Hiccups, gastric symptoms e.g. flatulence, vomiting, stomatitis, oral discomfort., abdominal pain, upper diarrhea, dry mouth, constipation. The following undesirable effects detailed in Table 1 are nicotine related adverse events for all oral dosage forms. Signs and symptoms of an overdose from nicotine lozenge would be expected to be the same as those of acute nicotine poisoning, including: weakness, perspiration, pallor, hyperhidrosis, salivation, throat burn, nausea, vomiting, diarrhoea, abdominal pain, hearing and visual disturbances (sensory disturbance), headache, tachycardia and cardiac arrhythmia, dyspnoea, dizziness, tremor, confusional state and asthenia. Prostration, hypotension, circulatory collapse, coma, respiratory failure, and terminal convulsions may ensue with large overdoses. The plasma concentrations of other active substances metabolised by CYP1A2 e.g. caffeine, paracetamol, phenazone, phenylbutazone, pentazocine, lidocaine, benzodiazepines, warfarin, oestrogen and vitamin B12 may also increase. However, the clinical significance of this effect for these active substances is unknown. However, if you're pregnant and can't stop smoking using willpower alone, you can use Nicotinell lozenges to help you. This will be safer for you and your baby than continuing to smoke. The lozenges deliver less nicotine (and none of the other potentially disease-causing agents) than would be obtained from cigarettes. However, you should aim to stop using Nicotinell lozenges as soon as possible, preferably after two to three months, because nicotine in any form has been shown to adversely affect the development of the baby, both in the womb and after birth. You can get more advice from your doctor or pharmacist.

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If you're not yet ready to stop smoking completely, Nicotinell lozenges can also help you to cut down the number of cigarettes you smoke each day, by using a lozenge instead of having a cigarette. This can make it easier to eventually stop smoking completely. How do Nicotinell lozenges work?

Drug Interactions: No information is available on interactions between Nicotinell Lozenge and other medicinal products. Nicotine patches like Nicoderm CQ deliver tiny doses of nicotine throughout the day, and they don’t require the extra maintenance of thinking about when you’re going to take your next dose. Smoking during pregnancy is associated with risks such as intra-uterine growth retardation, premature birth or stillbirth. Stopping smoking is the single most effective intervention for improving the health of both the pregnant smoker and her baby. The earlier abstinence is achieved the better. Nicotine passes to the foetus and affects its breathing movements and circulation. The effect on the circulation is dose-dependent.Vendrell K, et al. (2008). Chapter 17: Preventionstrategies for oral cancer in Preventionin Clinical Oral Health Care. St. Louis, MS: Mosby Elsevier. Shahab L, et al. (2016). Prevalence and impactof long-term use of nicotine replacement therapy in UK Stop-Smoking services:Findings from the ELONs study. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Excessive consumption of lozenges by subjects who have not been in the habit of inhaling tobacco smoke, could possibly lead to nausea, faintness and headache. The number of lozenges you use each day will depend on how much you smoke and if you are cutting down or completely quitting smoking. However, you should not use more than 30 lozenges daily.

Seizures: potential risks and benefits of nicotine should be carefully evaluated before use in subjects taking anti-convulsant therapy or with a history of epilepsy as cases of convulsions have been reported in association with nicotine. Initially, 1 lozenge should be taken every 1-2 hours. The usual dosage is 8-12 lozenges per day. For smoking cessation and smoking reduction with Nicotinell Lozenge, the maximum daily dose is 15 lozenges. Do not use more than one lozenge per hour.Use 1 lozenge every 1-2 hours for the first six weeks of your quit attempt.Try to think ahead about when you might get a craving for a cigarette, and then use a lozenge beforethe craving happens. To ensure that your body gets enough nicotine to ease your withdrawal symptoms, it is best to use at least 9 lozenges per day for the first six weeks.