Suzanne Carr (1995). "MS thesis". Archived from the original on November 8, 2009 . Retrieved May 16, 2007. (citing Andrew Sherratt) Speer, William (1870). The oldest and the newest empire: China and the United States. Hartford, Conn., S. S. Scranton and company; Philadelphia, Parmelee & co.; [etc., etc.] Latimer, Dean, and Jeff Goldberg with an Introduction by William Burroughs. Flowers in the Blood: The Story of Opium. New York: Franklin Watts, 1981 Inglis, Lucy, Milk of Paradise: A History of Opium, Pan Macmillan, London, 2018. **Review: Julie Peakman: "Not Just Smelling the Flowers", History Today History Today Vol. 68/10, October 2018, pp.102–103.

The history of opium in China began with the use of opium for medicinal purposes during the 7th century. In the 17th century the practice of mixing opium with tobacco for smoking spread from Southeast Asia, creating a far greater demand. [1] Lomax, Elizabeth (1973). "The Uses and Abuses Of Opiates In Nineteenth-Century England". Bulletin of the History of Medicine. 47 (2): 167–176. ISSN 0007-5140. JSTOR 44447528. PMID 4584236 . Retrieved May 31, 2022. a b c M J Brownstein (June 15, 1993). "A brief history of opiates, opioid peptides, and opioid receptors". Proceedings of the National Academy of Sciences of the United States of America. 90 (12): 5391–5393. Bibcode: 1993PNAS...90.5391B. doi: 10.1073/pnas.90.12.5391. PMC 46725. PMID 8390660. Most illicit heroin is sold as a white or brownish powder and may be "cut" with other substances such as sugar, starch, powdered milk, or quinine. It can also be cut with strychnine or other poisons. As the power of the Roman Empire declined, the lands to the south and east of the Mediterranean Sea became incorporated into the Islamic Empires. Some Muslims believe hadiths, such as in Sahih Bukhari, prohibits every intoxicating substance, though the use of intoxicants in medicine has been widely permitted by scholars. [16] Dioscorides' five-volume De Materia Medica, the precursor of pharmacopoeias, remained in use (which was edited and improved in the Arabic versions [17]) from the 1st to 16th centuries, and described opium and the wide range of its uses prevalent in the ancient world. [18]Opium prohibition in China began in 1729, yet was followed by nearly two centuries of increasing opium use. A massive destruction of opium by an emissary of the Chinese Daoguang Emperor in an attempt to stop opium smuggling by the British led to the First Opium War (1839–1842), in which Britain defeated China. After 1860, opium use continued to increase with widespread domestic production in China. By 1905, an estimated 25 percent of the male population were regular consumers of the drug. Recreational use of opium elsewhere in the world remained rare into late in the 19th century, as indicated by ambivalent reports of opium usage. [44] In 1906, 41,000 tons were produced, but because 39,000 tons of that year's opium were consumed in China, overall usage in the rest of the world was much lower. [48] These figures from 1906 have been criticized as overestimates. [49] A Chinese opium house; photographed in 1902 Donna Young (April 15, 2007). "Scientists Examine Pain Relief and Addiction". Archived from the original on December 6, 2007 . Retrieved June 6, 2007. UNODC – Bulletin on Narcotics – 1950 Issue 3 – 003". United Nations: Office on Drugs and Crime . Retrieved May 5, 2021. Benjamin Pui-Nin Mo & E. Leong Way (October 1, 1966). "An Assessment Of Inhalation As A Mode Of Administration Of Heroin By Addicts". Journal of Pharmacology and Experimental Therapeutics. 154 (1): 142–151. PMID 5924312 . Retrieved June 6, 2007. Santella, Thomas M.; Triggle, D. J. (2009). Opium. Facts On File, Incorporated. p.8. ISBN 9781438102139.

John Richards (May 23, 2001). "Opium and the British Indian Empire" . Retrieved September 24, 2007. Dioscorides,Introduction to The Herbal of Dioscorides the Greek Poppy crop from the Malwa in India (probably Papaver somniferum var. album [1]) Opium has a harm. Opium is a poison, undermining our good customs and morality. Its use is prohibited by law. Now the commoner, Yang, dares to bring it into the Forbidden City. Indeed, he flouts the law! a b c d e f g h i j Paul L. Schiff Jr. (2002). "Opium and its alkaloids". American Journal of Pharmaceutical Education. Archived from the original on October 21, 2007 . Retrieved May 8, 2007.

Heroin methods of use

The opium trade under the Chinese Communist Party was important to its finances in the 1940s. [82] Peter Vladimirov's diary provided a first hand account. [83] Chen Yung-fa provided a detailed historical account of how the opium trade was essential to the economy of Yan'an during this period. [84] Mitsubishi and Mitsui were involved in the opium trade during the Japanese occupation of China. [85] During the Communist era in Eastern Europe, poppy stalks sold in bundles by farmers were processed by users with household chemicals to make kompot (" Polish heroin"), and poppy seeds were used to produce koknar, an opiate. [99] Obsolescence [ edit ] Apothecary vessel for storage of opium as a pharmaceutical, Germany, 18th or 19th century Joyce A. Madancy (April 2004). "The Troublesome Legacy of Commissioner Lin" . Retrieved September 25, 2007. The first problem for do-it-yourself growers is that it would be hard to plant enough poppies to make an appreciable amount of drug without being noticed, Wankel said. The plants can grow more than 3 feet (0.9 meters) tall and are topped with brightly colored flowers that look a bit like frilly tulips. Any reasonably sized plot of these flowers would easily stand out in terrestrial or aerial surveys done by law enforcement agencies, Wankel said.

Karl A. Sporer, M.D. (April 6, 1999). "Acute Heroin Overdose". Annals of Internal Medicine. 130 (7): 584–590. doi: 10.7326/0003-4819-130-7-199904060-00019. PMID 10189329. S2CID 22949289.

cocktails

Marc Andre Matten, ed. (December 9, 2011). Places of Memory in Modern China: History, Politics, and Identity. BRILL. p.271. ISBN 978-90-04-21901-4. As more potent drugs have appeared on the market, overdose deaths have spiked. Since 1999, according to the CDC, opioid overdose deaths have quadrupled. In 2015, the agency reported that 33,091 Americans died of a drug overdose involving a prescription or illegal opioid drug. a b c d e f g Dikotter, Frank (2004). Narcotic Culture: A History of Drugs in China. Hurst. p.3. ISBN 978-0226149059. Carstairs C. (2006). "Jailed for Possession: Illegal Drug Use, Regulation, and Power in Canada, 1920–61". Archived from the original on January 25, 2003. Opium poppies are popular and attractive garden plants, whose flowers vary greatly in color, size and form. A modest amount of domestic cultivation in private gardens is not usually subject to legal controls. In part, this tolerance reflects variation in addictive potency. A cultivar for opium production, Papaver somniferum L. elite, contains 91.2 percent morphine, codeine, and thebaine in its latex alkaloids, whereas in the latex of the condiment cultivar "Marianne", these three alkaloids total only 14.0 percent. The remaining alkaloids in the latter cultivar are primarily narcotoline and noscapine. [115]

Between 400 and 1200 CE, Arab traders introduced opium to China, and to India by 700. [19] [1] [12] [20] The physician Muhammad ibn Zakariya al-Razi of Persian origin ("Rhazes", 845–930 CE) maintained a laboratory and school in Baghdad, and was a student and critic of Galen; he made use of opium in anesthesia and recommended its use for the treatment of melancholy in Fi ma-la-yahdara al-tabib, "In the Absence of a Physician", a home medical manual directed toward ordinary citizens for self-treatment if a doctor was not available. [21] [22] In the U.S. in the 1800's, opium dens sprang up in the west, such as in San Francisco's Chinatown, and spread east to New York. Chinese immigrants who came to the U.S. for railroad and the gold rush work often brought their opium with them for its intoxicating and pain-relieving effects. Professor Arthur C. Gibson. "The Pernicious Opium Poppy". University of California, Los Angeles. Archived from the original on October 20, 2013 . Retrieved February 22, 2014. Anderson, Stuart; Berridge, Virginia (2000). "Opium In 20th-Century Britain: Pharmacists, Regulation And The People". Addiction. 95 (1): 23–36. doi: 10.1046/j.1360-0443.2000.951234.x. PMID 10723823.From the earliest finds, opium has appeared to have ritual significance, and anthropologists have speculated ancient priests may have used the drug as a proof of healing power. [11] In Egypt, the use of opium was generally restricted to priests, magicians, and warriors, its invention is credited to Thoth, and it was said to have been given by Isis to Ra as treatment for a headache. [1] A figure of the Minoan "goddess of the narcotics", wearing a crown of three opium poppies, c. 1300 BCE, was recovered from the Sanctuary of Gazi, Crete, together with a simple smoking apparatus. [14] [15] The production methods have not significantly changed since ancient times. Through selective breeding of the Papaver somniferum plant, the content of the phenanthrene alkaloids morphine, codeine, and to a lesser extent thebaine has been greatly increased. In modern times, much of the thebaine, which often serves as the raw material for the synthesis for oxycodone, hydrocodone, hydromorphone, and other semisynthetic opiates, originates from extracting Papaver orientale or Papaver bracteatum. William Travis Hanes; Frank Sanello (2004). Opium Wars: The Addiction of One Empire and the Corruption of Another. Sourcebooks, Inc. pp.78–. ISBN 978-1-4022-0149-3.