Although the gelatin forms of collagen can be consumed and absorbed to provide the various benefits of collagen, it takes longer to digest, and some collagen may be lost in the process. In general, however, both products are roughly equivalent in the amounts of proteins and amino acids. The effect of post-exercise protein supplementation with collagen peptides compared with placebo on the muscle mass and muscle function following resistance training of elderly sarcopenia patients was studied [ 75]. Additional dietary protein can increase the muscle protein synthesis rate after exercise and reduce the decomposition of muscle protein after resistance exercise. A total of 53 men with a mean age of 72.2 were recruited in the study. The results showed that 60 min of resistance exercise, performed three times per week, could significantly increase muscle mass, muscular strength, and motor control in sarcopenia patients. In addition, the study also showed that the combination of resistance exercise and collagen peptide supplementation resulted in a significant improvement in muscular strength as well as a significant increase in muscle mass and decrease in fat mass compared to placebo.

Collagen capsules: Capsules are generally less expensive and easy to travel with. Unlike liquid collagen, capsules don't contain artificial colors, flavors, or preservatives. Collagen capsules are usually less potent than powdered or liquid forms, so you may need to take more than one capsule at a time. The most common animal collagen sources are human collagen, bovine, porcine, and marine organisms such as fish [ 24]. Despite the risk of bovine spongiform encephalopathy (BSE), bovine collagen is widely used in collagen-based products. The immune response to bovine collagen has been studied. A clinical study of 705 patients treated with a bovine collagen implant and a small percentage of patients had both the cellular and humoral types of the immune response [ 25]. Keefe, et al. showed that side effects to bovine collagen implants occurred in a small percentage of treated patients and these adverse reactions were resolved as the implant was resorbed by the patients [ 26]. Angiotensin-I converting enzyme (ACE) plays a key role in elevating blood pressure, and therefore, effective ACE inhibition can reduce blood pressure [ 27]. Bovine collagen is a promising precursor of ACE-inhibitory peptides in silico and in vitro protein digestions [ 28, 29]. The porcine collagen is widely used for extracting collagen as the bovine collagen. Porcine collagen does not cause much allergic response because it is almost similar to human collagen. Collagen peptides are promising for osteoporosis treatment and prevention. Porcine collagen peptides could be used to treat and prevent osteoporosis [ 30]. Porcine collagen membrane was tested in vitro and in vivo studies for guided bone regeneration [ 31]. The result indicated that the use of the porcine collagen membranes did not cause foreign body reactions and the porcine collagen membranes were biocompatible. So, this explains why the market is saturated with products promising to support our decreasing collagen levels. But, with so many brands serving up collagen supplements, how can we really tell which ones offer tangible benefits? Marine collagen is becoming popular for maintaining skin health. Evans et al. performed a randomized, placebo-controlled, blind study to evaluate the efficacy of hydrolyzed marine collagen on skin health in women between 45 and 60 years of age. The results supported that the use of fish-derived hydrolyzed collagen could improve skin health in an aging population [ 53]. a) A triplex helix structure plotted from RCSB protein data bank ( https://www.rcsb.org/ accessed on 1 May 2021). ( b) A triplex helix structure model.

Yes, it needs to be taken daily for good results. Make sure to follow the instructions on your collagen product. How long does collagen take to start working? Marine collagen has been shown to help calcium absorption and other minerals that are key for bone strength. Consuming marine collagen can help support healthy blood sugar levels, lower cholesterol levels, and reduce inflammation. Marine collagen also has antibacterial properties and may help with fighting infection. It's perfect for promoting weight loss and appetite suppression. de Miranda RB, Weimer P, Rossi RC. Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis. Int J Dermatol. 2021;60(12):1449-1461. doi:10.1111/ijd.15518

Jin Tak Y, Jin Kim Y, Gyu Lee J, et al. Effect of oral ingestion of low-molecular collagen peptides derived from Skate ( Raja Kenojai) skin on body fat in overweight adults: A randomized, double-blind , placebo-controlled trial. Mar Drugs. 2019 Mar;17(3):157. doi:10.3390/md17030157 Collagen has porcine and bovine origins that cow and pig skins and bones are the main sources of collagen. However, due to religious constraints concerning the avoidance of porcine and bovine products or other reasons such as the outbreak of BSE, the marine collagen source is being highly considered by the industry as an important alternative [ 11, 36, 37]. Marine collagens have the advantages of a high yield and no disease transmission risk that can be obtained from invertebrate marine animals or fishes. Mammalian collagens have higher thermal stability than fish collagens due to the lower imino acid contents of fish collagens compared with mammalian collagens [ 38]. The thermal stability is related to body temperature and living environment and the low thermal stability of marine collagens restricts its applications [ 39]. The mechanical strength of marine collagen is poorer than collagen extracted from bovine because it is less crosslinked. After the crosslinking treatment, marine collagen can be used as a biomaterial in tissue engineering [ 40]. Despite some limitations, the marine collagen is an appealing option for product developers because the source is cheap and no risk of BSE. In the latest 20 years, more than 175 chemical entities and 28 marine natural products were discovered. Marine organisms, as well as their wastes, are good sources of collagen for many applications [ 41, 42, 43, 44, 45]. Marine collagen is a collagen supplement derived from marine life. This means that the collagen is removed from fish, crustaceans, and other sea life. The parts of the marine life are boiled down to make gelatin. This gelatin can then be hydrolyzed to provide an easier method for absorbing these collagen particles.From the above discussions, compared with other drugs, collagen treatment has many advantages. However, it does not mean that the collagen treatment is absolutely safe. Some people may have an allergic reaction to collagen treatment. For example, some people may have a shellfish allergy and could experience anaphylaxis if they take marine collagen supplements. The other source of collagen may have an allergy problem. There are types of collagen supplements that are not hydrolyzed. These are often made directly from the gelatin product created when sourcing collagen from the various animals used for the product. This gelatin can be easily transformed into tablets, powders, or other products for easy consumption. Our Hydrolysed Marine Collagen is derived from wild fish such as Cod (Gadidae) that are sourced in an environmentally-friendly and sustainable way from various regions across the world (EU, South America, Southeast Asia). Our hydrolysed collagen has NO artificial colours and flavours; and NO excipients, binders or fillers -- only pure and active ingredients. National Center for Biotechnology Information. PubChem Compound Summary for CID 656852, Glycyrrhizinate Dipotassium. Li YS, Xiao W feng, Luo W. Cellular aging towards osteoarthritis. MAD. 2017;162:80-84. doi:10.1016/j.mad.2016.12.012