When used after facial resurfacing, avoid placing pressure upon the dressing. Lift and reposition the dressing at least every second day. Adamietz IA, Mose S, Haberl A, et al (1994) Effect of Self-Adhesive, Silicone-Coated Polyamide Net Dressing on Irradiated Human Skin. Radiat Oncol Investig 2(6): 277-282 Mepitel is clinically provento heal scalds faster and with less pain and cost, compared to silver sulfadiazine When using for the fixation of skin grafts and protection of blisters, the dressing should not be changed before the fifth day post application

Mepitel One used after facial resurfacing: avoid placing pressure upon the dressing lift and reposition the dressing at least every second day.Collin (2009) describes the use of Mepitel ® One following hand surgery in a non-comparative, ten patient case series. The author found dressing conformability was rated by the investigator as ‘good’ to ‘very good’; handling at application and ease of removal were generally rated as ‘easy’ to ‘very easy’. The patients also rated dressing conformability and comfort as ‘good’ to ‘very good’. No pain was associated with the removal of the Mepitel One dressings. There were no reports of leakage or dressing displacement. All wounds responded well and were associated with, at worst, minimal bleeding or exudation (as would be expected of this type of wound). No odour or signs of infection/ inflammation were reported. The condition of the peri-wound skin was generally healthy although mild maceration developed around one of the wounds. When used on bleeding wounds or wounds with high viscosity exudate, Mepitel should be covered with a moist absorbent dressing pad. When Mepitel One is used for the fixation of skin grafts, the dressing should not be changed before the fifth day post application.

Waring M, Bielfeldt S, Mätzold K, Wilhelm KP, Butcher M (2011) An evaluation of the skin stripping of wound dressing adhesives. J Wound Care 20(9): 412-422

Frequency of Change

Collin O (2009) Use of Mepitel One dressing following hand surgery: a case study series. Poster presentation. Wounds UK Conference, United Kingdom When used on bleeding wounds or wounds with high-viscosity exudate, Mepitel® One should be covered with a moist, absorbent dressing pad.

Mepitel has an open mesh structure that allows exudate to pass through into a secondary absorbent dressing and enables the delivery of topical treatments. Mepitel allows secondary dressings to be changed without disturbing the wound bed. The dressing reduces the need for frequent primarydressing changes and allows secondary dressing changes without disturbing healing. In an open, two-arm, multi-centre, parallel-group randomised controlled trial of outpatients with moderately exudating, uncomplicated acute wounds, David et al (2017) compared Mepitel ® One with a soft silicone adhesive layer with a lipido-colloid adhesive layer. In 123 patients, the randomised clinical trial found Mepitel ® One was significantly less painful to remove compared to a lipido-colloid adhesive layer. A comparison on healing by day 21 was made. At this time, significantly more patients treated with Mepitel One had healed compared to those treated with a lipido-colloid adhesive layer. Safetac also protects new tissue and intact skin, so wounds remain undisturbed to support faster healing. Mepitel One seals the wound margins to protect skin from damaging leaks and maceration. The design includes a Safetac ® interface which seals the wound edges, preventing the exudate to leak onto the surroundingskin, thus minimising the risk for maceration . Safetac interface also minimises damaging the wound or surrounding skin orexposing the patient to additional pain at dressing changes . If the product is not used properly on burns treated with meshed grafts or after facial resurfacing imprints can occur.If used on epidermolysis bullosa patients, employ extra surveillance at dressing changes. Adhesion level of Mepitel® One is somewhat higher than that of Mepitel®. The wound should be inspected for signs of infection according to clinical practice. Consult a healthcare professional for the appropriate medical treatment. Safetac also protects new tissue and intact skin – so wounds remain undisturbed to support faster natural healing . And it seals the wound margins to protect skin from damaging leaks and maceration .