Piek CJ, Rutteman GR, Teske E. Evaluation of the results of a L-asparaginase-based continuous chemotherapy protocol versus a short doxorubicin-based induction chemotherapy protocol in dogs with malignant lymphoma. Vet Q. 1999;21:44–9. Last week yet another socialisation session was held at the Christchurch branch of Canine Complete and it was another full house of hounds! dogs entered the study. Lymphoma types included multicentric (n = 123), alimentary (n = 13), miscellaneous (n = 7), and mediastinal lymphoma (n = 1). Overall response rate was 83.3% (B-cell: 86.6%, T-cell: 79.4%). Complete remission (CR) was achieved in 72.2% (B-cell: 77.3%, T-cell: 67.6%) and partial remission (PR) in 11.1% (B-cell: 9.3%, T-cell: 11.8%) of the dogs. Median duration of first CR amounted to 242 days (B-cell: 263 d, T-cell: 161 d). Median survival in dogs with CR was 374 days (B-cell: 436 d, T-cell: 252 d), and median overall survival time was 291 days (B-cell: 357d, T-cell: 210d). Immunophenotype demonstrated an independent significant influence on duration of remission and survival in the whole group. Findings of splenic and hepatic cytology were not significant associated with patient outcome. Treatment was well tolerated; the majority of adverse events were classified as grade 1 or 2. Conclusions Limmer, S., Nerschbach, V., Eberle, N. et al. Efficacy and tolerability of a 12-week combination chemotherapy followed by lomustine consolidation treatment in canine B- and T-cell lymphoma.

Immunophenotyping revealed B-cell lymphoma in 97 dogs (67.3%) and T-cell lymphoma in 34 (23.6%), in the remaining dogs phenotyping was not technically possible (n = 8; 5.6%) or yielded unclear results (n = 5; 3.5%).But we aren’t doing that, instead we are putting every family through the ringer by hiking up every cost that a family CAN’T bypass to bolster the coffers of the greedy by robbing the needy, seems like an inverted Robin Hood way to run a country if you ask me… Feel free to come in and say hello and meet him first hand and see if between Zeus and I we can help you overcome any fears you may have on this breed or large breeds in general. Craig really educated us on how Shanti's psychology and physicality should work and why she had been so out of balance up to this point. These pictures may not look like much, but this is the calmest and closest our dogs have been together in a while.

Following the important paradigm shift from implicating long-term—sometime life-long—chemotherapy for lymphoma dogs on to the acceptance of discontinuous treatments allowing for chemotherapy-free periods of variable duration, veterinary oncology is facing a further major transformation in how we define and treat canine lymphoma. It is now widely accepted that lymphoma does not represent a single disease entity but summarizes a diverse group of neoplasms with varying biologic behaviors and prognoses [ 31]. Morgan E, O’Connell K, Thomson M, Griffin A. Canine T cell lymphoma treated with lomustine, vincristine, procarbazine, and prednisolone chemotherapy in 35 dogs. Vet Comp Oncol. 2018;16:622–9.Normality of continuous data was tested by the Kolmogorov–Smirnov test. Based on this, non-parametric tests were used for significance testing. Our products are 100% natural and have the perfect ratio of meat, bone and offal to satisfy your dogs appetite. By feeding your dog natural meat, you are ensuring your dogs diet is free from additives, preservatives and unnecessary colourings & flavour enhancers!

I also want to personally thank everyone too who has chosen me to help with their dogs both this year and every since I started this (some seven years ago now!), from the mad to the bad and every dog in-between it has been a pleasure so far and I welcome even more of you next year! Keller ET, MacEwen EG, Rosenthal RC, Helfand SC, Fox LE. Evaluation of prognostic factors and sequential combination chemotherapy with doxorubicin for canine lymphoma. J Vet Intern Med. 1993;7:289–95. It’s a very important issue for the discerning dog owner, when choosing the right dog grooming professional for their special pet. Zenker I, Meichner K, Steinle K, Kessler M, Hirschberger J. Thirteen-week dose-intensifying simultaneous combination chemotherapy protocol for malignant lymphoma in dogs. Vet Rec. 2010;167:744–8. I was recently called to see if I could help two Bull Terriers who littearlly couldn’t be in the same room together without fighting to the point the dogs were separated whenever indoors…Zeus is 3.5yrs old and one of the largest Rottweilers I have seen in quite some time but he is a gentle giant and just wants to be loved the way small dogs are! I had spent more time loving them too much than making sure that the rules and boundaries were being kept up and he was right too. I had been unknowingly making them unbalanced and anxious therefore causing conflict and aggression between them and Alfie started guarding me and his behaviour had changed as with his brother. They didn't trust each other anymore. Our 9yr old collie was hiding when they argued. I felt awful!!!