Improves LDL, HDL and TG (Triglyceride) levels, while also reducing fasting and circulating insulin levels Personally I don’t like to add a whole lot of supplements to my daily routine in one go. So I’d start by adding Magnesium (then understand the affect), add Theanine (again, understand affect), Apigenin then Inositol. M.G., et al., Inositol for subfertile women with polycystic ovary syndrome. Cochrane Database Syst Rev, 2018. 12(12): p. Cd012378. Fruzzetti F, Perini D, Russo M, Bucci F, Gadducci A. Comparison of two insulin sensitizers, metformin and myo-inositol, in women with polycystic ovary syndrome (PCOS). Gynecol Endocrinol. 2017;33(1):39-42. View abstract.

Andrew Huberman Sleep Supplements Cocktail - 6 He Takes in 2023

Zhang JQ, Xing C, He B. Short period-administration of myo-inositol and metformin on hormonal and glycolipid profiles in patients with polycystic ovary syndrome: a systematic review and updated meta-analysis of randomized controlled trials. Eur Rev Med Pharmacol Sci 2022;26(6):1792-1802. View abstract. Combination products like Ovasitol are safe to take during pregnancy and breastfeeding. There are no expected side effects. M. and D.T. Archer, Metformin and Micronutrient Status in Type 2 Diabetes: Does Polypharmacy Involving Acid-Suppressing Medications Affect Vitamin B12 Levels? Diabetes Metab Syndr Obes, 2020. 13: p. 2093-2108. H., et al., Comparative efficacy of oral insulin sensitizers metformin, thiazolidinediones, inositol, and berberine in improving endocrine and metabolic profiles in women with PCOS: a network meta-analysis. Reprod Health, 2021. 18(1): p. 171.Inositol-based compounds are involved in neurotransmitter activity modulation, giving inositol potential benefits in promoting mental and emotional health. Some research indicates inositol may be beneficial for supporting stable moods. (7-9) Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(10):967-72. View abstract.

Inositol: Benefits, Side Effects, Dosage, Interactions

Breast-feeding: There isn't enough reliable information to know if inositol is safe to use when breast-feeding. Stay on the safe side and avoid use.Phelps DL, Watterberg KL, Nolen TL, et al. Effects of Myo-inositol on Type 1 Retinopathy of Prematurity Among Preterm Infants <28 Weeks' Gestational Age: A Randomized Clinical Trial. JAMA. 2018;320(16):1649-1658. View abstract. Bahadur A, Arora H, Ravi AK, et al. Comparison of Clinical, Metabolic and Hormonal Effects of Metformin Versus Combined Therapy of Metformin With Myoinositol Plus D-Chiro-Inositol in Women With Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial. Cureus 2021;13(6):e15510. View abstract. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. We avoid using tertiary references. We link primary sources — including studies, scientific references, and statistics — within each article and also list them in the resources section at the bottom of our articles. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Hashemi Tari S, Sohouli MH, Lari A, Fatahi S, Rahideh ST. The effect of inositol supplementation on blood pressure: A systematic review and meta-analysis of randomized-controlled trials. Clin Nutr ESPEN 2021;44:78-84. View abstract. Inositol is a type of sugar, found in the brain and other tissues, which mediates cell signal conversion in response to hormones, neurotransmitters and growth factors. When these external signals reach the cell they are converted into internal messengers, for which myo-inositol is involved 5 The cellular language of myo- inositol signaling– Glenda E. Gillaspy (2011).