The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular daily use of paracetamol with increased risk of bleeding; occasional doses have no significant effect.

The following Lemsip Cold And Flu Sachets Ingredients are contained within each sachet, this includes: The product should be avoided during lactation unless recommended by a healthcare professional. There are limited data on the use of phenylephrine in lactation. Immediate medical advice should be sought in the event of an overdose, even if the patient feels well because of the risk of delayed serious liver damage (see section 4.9). Paracetamol is excreted in breast milk, but not in a clinically significant amount. Available published data do not contraindicate breast feeding. Caution should be taken when paracetamol is used concomitantly with flucloxacillin as concurrent intake has been associated with high anion gap metabolic acidosis, especially in patients with risks factors (see section 4.4)Liver damage is possible in adults who have taken 10 g or more of paracetamol. Ingestion of 5 g of more of paracetamol may lead to liver damage if the patient has risk factors (see below). Acne Acne is a common skin condition that affects most people at some point. It causes spots, oily skin and sometimes skin that’s hot or painful to touch. Acne most commonly develops on the face. Additional symptoms may include, hypertension, and possibly reflex bradycardia. In severe cases confusion, seizures and arrhythmias may occur. However the amount required to produce serious phenylephrine toxicity would be greater than that required to cause paracetamol-related liver toxicity. Other Lemsip Cold and Flu Sachets Ingredients: Citric acid, sucrose, aspartame, sodium citrate, saccharin sodium, caster sugar, curcumin and lemon flavour. Like with all medicine, Lemsip Cold And Flu Lemon Sachets Side Effects can occur but these aren’t experienced by everyone. If you experience any of these Lemsip Cold And Flu Lemon Sachets side effects, especially if any of them are getting progressively worse, immediately stop and speak to your doctor as soon as possible.

Symptoms of paracetamol overdose in the first 24 hours are pallor, nausea, vomiting, anorexia and abdominal pain. Liver damage may become apparent 12 to 48 hours after ingestion. Abnormalities of glucose metabolism and metabolic acidosis may occur. In severe poisoning, hepatic failure may progress to encephalopathy, haemorrhage, hypoglycaemia, cerebral oedema and death. Acute renal failure with acute tubular necrosis, strongly suggested by loin pain, haematuria and proteinuria, may develop even in the absence of severe liver damage. Cardiac arrhythmias and pancreatitis have been reported.

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a) Is on long-term treatment with carbamazepine, phenobarbitone, phenytoin, primidone, rifampicin, St John's Wort or other drugs that induce liver enzymes. Each of the Lemsip Cold And Flu Sachets contains three active ingredients. Paracetamol, Phenylephrine hydrochloride and ascorbic acid (Vitamin C). All of them combine to provide short term relief to the above symptoms. Do not take any other cold, flu, decongestant products when using Lemsip Cold Flu Sachets. Lemsip Max Cold & Flu Lemon 10 Sachets Sympathomimetic amines: concomitant use of phenylephrine with other sympathomimetic amines can increase the risk of cardiovascular side effects. Asthma Our Asthma service is ideal in emergencies when you are unable to visit your own doctor and need your inhaler urgently. It is designed for emergencies and not regular use and requires you to have add a recent asthma review.

Directions How to take: Pour one sachet of powder into a mug and fill with hot, but not boiling water. Stir until dissolved. If preferred, sweeten to taste with sugar, honey or your usual sweetener. Suitable for adults and children 12 years and over Below is a list of Lemsip Cold And Flu Lemon Sachets Side Effects experienced more, or less when people have used Lemsip Sachets. For a full list, please refer to the patient information leaflet. Caution should be taken when paracetamol is used concomitantly with flucloxacillin as concurrent intake has been associated with high anion gap metabolic acidosis, especially in patients with risks factors (see section 4.4). Acid Reflux Heartburn is a burning feeling in the chest caused by stomach acid travelling up towards the throat (acid reflux). If it keeps happening, it’s called gastro-oesophageal reflux disease (GORD). Treatment with activated charcoal should be considered if the overdose has been taken within 1 hour. Plasma paracetamol concentration should be measured at 4 hours or later after ingestion (earlier concentrations are unreliable). Treatment with N-acetylcysteine may be used up to 24 hours after ingestion of paracetamol, however, the maximum protective effect is obtained up to 8 hours post-ingestion. The effectiveness of the antidote declines sharply after this time. If required the patient should be given intravenous N-acetylcysteine, in line with the established dosage schedule. If vomiting is not a problem, oral methionine may be a suitable alternative for remote areas, outside hospital. Management of patients who present with serious hepatic dysfunction beyond 24 hours from ingestion should be discussed with the NPIS or a liver unit.Patients with rare hereditary problems of fructose intolerance, glucose- galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine.

Epidemiological studies in human pregnancy have shown no ill effects due to paracetamol used in the recommended dosage.

First and foremost the Lemsip Cold and Flu Sachets Dosage should be taken exactly as described in the patient information leaflet. Do not increase your dosage beyond what is recommended. If more than the recommended dosage is taken then it will more than likely result in a paracetamol overdose. The maximum daily dose of this product is equivalent to 23.8 % of the WHO recommended maximum daily intake for sodium.