The total daily dosage of Lipsore 5% should be based on the type or severity of infection and given in equally divided doses based on consideration of degree of susceptibility of the pathogens, renal function and body-weight. Genital herpes simplex virus is very contagious when blisters are present. You should not have sex from the time your symptoms first start until they are fully over, as there is a high chance of passing on the virus. Summary of Product Characteristics: Zovirax Cold Sore cream. GlaxoSmithKline Consumer Healthcare. Revised March 2014. If you are not sure that your symptoms are caused by a cold sore then please consult your doctor orpharmacist before use. Do not use Lipsore 5% w/wCream:

Lipsore Cream is used for the treatment of cold sores on the lips and face. It contains aciclovir, which belongs to a group of medicines called antivirals. Lipsore Cream helps to slow the growth of the virus, and speeds up the healing of cold sore blisters. What are Cold sores? Foetal abnormalities were observed in non-standard tests in rats, but only following such high subcutaneous doses that maternal toxicity was produced. The clinical relevance of these findings is uncertain. Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines includingmedicines obtained without prescription. Pregnancy and Breastfeeding: Lipsore 5% w/w cream contains cetyl alcohol and propylene glycol which may cause local skin reactions(skin irritation and redness). 3. Howto use Lipsore 5% w/wCream Lipsore 5% w/w Cream is for use on the skin only. It is not to be taken internally. Wash your hands again. Herpes simplex isinfectious and you should try to avoid touching theinfected skin with your hands or with towels, etc.to prevent spreadingthe infection.

Treatment should be continued for at least 4 days.If the infection has not healed after this time,treatment can be continued for up to 5 days more. In internationally accepted standard tests the systemic administration of Aciclovir did not produce embryotoxic or teratogenic effects in rabbits, rats or mice. If you have ever had an allergic reaction to Aciclovir, valaciclovir, propylene glycol or any other ingredients of the preparation

Best used at the time of the first tingling sensation but will also reduce the healing time after the blister has formed. Tell your doctor or pharmacist before use ifyou are taking any regular medication on prescription or over the counter products. In this case let your doctor know immediately. He will decide if you should continue with Lipsore 5% w/wCream. Very Rare (< 1/10,000):

If you take or use too much

In vitro and in vivo studies of aciclovir cream and aciclovir ointment versus oral aciclovir were carried out to determine the bioavailability of aciclovir in human skin. The in vitro studies used human skin biopsates, whilst the bioassays either used human skin grafts on mice or were carried out in the human eye (3 patients). Dose adjustment of IV for patients with acute or chronic renal impairment, based on Creatinine Clearance, Cr Cl (mL/min/1.73 m2): The required dose of Lipsore 5% IV should be administered by slow intravenous infusion over a one-hour period. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk, 9th edition (2011) ed. Briggs, G., Freeman, R. and Yaffe, S. Lippincott Williams & Wilkins, Philadelphia. To work at its best, Lipsore 5% w/wCream shouldbe started as soon as possible after the firstsymptoms of infection appear.

Dose adjustment of Tablet for patients with acute or chronic renal impairment, based on Creatinine Clearance, Cr Cl (mL/min/1.73 m2): Aciclovir does cross the placenta (Schaefer, 2007 and Briggs, 2011) however, following topical use of aciclovir there is minimal absorption through the skin (Schaefer, 2007) and systemic exposure will be low. There is also significant experience of systemic aciclovir use in pregnancy and no evidence of an increased risk of congenital defects, adverse foetal or neonatal outcomes were found during a manufacturer - CDC organised pregnancy registry between 1984 and 1999 (Briggs, 2011). Three standard animal studies revealed no teratogenic effects although abnormal thymus and immune system resulted in rats when doses causing maternal toxicity were used (Briggs, 2011).Moisturize your lips with a hydrating lip balm immediately after exfoliating. [15] X Expert Source Tymia Yvette The reconstituted solution should be used within 12 hours. Refrigeration of reconstituted solution may result in the formation of a precipitate which will re-dissolve at room temperature. By reporting side effects you can help provide more information on the safety of this medicine. 5. How to store Lipsore 5% w/w Cream Keep out of the sight and reach of children. If you have ever had an allergic reaction to Aciclovir, valaciclovir, propylene glycol or any other ingredients ofthe preparation (see section 6 for a complete list of ingredients).