Bakanlar Kurulu Kararı - Karar Sayısı: 2011/1310". Resmî Gazete, Sayı: 27845 (in Turkish). Başbakanlık Mevzuatı Geliştirme ve Yayın Genel Müdürlüğü [General Directorate of Legislation Development and Publication] (published February 13, 2011). January 7, 2011. Experience: 22mg 2C-B (oral) / 100ug 1P-LSD (sublingual) - My first time tripping alone (2 days in a row)

You have to read the book to fully appreciate what he has done for science, for the appreciation of sympathomimetic amines that we have today. PLUS THREE (+++) Not only are the chronology and the nature of a drug’s action quite clear, but ignoring its action is no longer an option. The subject is totally engaged in the experience, for better or worse.

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PIHKAL (Phenethylamines I Have Known And Loved) is a unique book written by renowned psychopharmacologist Alexander Shulgin and his wife Ann Shulgin. This book gives details of their research and investigations into the use of psychedelic drugs for the study of the human mind, and is also a love story. phen-ethyl-amine \fen-'eth-al-a-,men\ n. [ phenylfr. F. phène, fr. Gk. phainein, to show (from its occurrence in illuminating gas)+ ethyl (+ yl) + amine fr. NL ammonia] 1: A naturally occurring compound found in both the animal and plant kingdoms. It is an endogenous component of the human brain. 2: Any of a series of compounds containing the phenethylamine skeleton, and modified by chemical constituents at appropriate positions in the molecule. Introduction As with PIHKAL, the Shulgins were motivated to release the synthesis information as a way to protect the public's access to information about psychedelic compounds, a goal Alexander Shulgin has noted many times. [1] Following a raid of his laboratory in 1994 by the United States DEA, [2] Richard Meyer, spokesman for DEA's San Francisco Field Division, stated that "It is our opinion that those books [referring to the previous work, PIHKAL] are pretty much cookbooks on how to make illegal drugs. Agents tell me that in clandestine labs that they have raided, they have found copies of those books." TIHKAL: The Continuation is a 1997 book written by Alexander Shulgin and Ann Shulgin about a family of psychoactive drugs known as tryptamines. A sequel to PIHKAL: A Chemical Love Story, TIHKAL is an acronym that stands for "Tryptamines I Have Known and Loved". so basically, this is a book by a chemist who has devoted his career to making and exploring psychedelics. what if you take the mescaline molecule and swap out this atom on the benzene ring? etc. etc. etc. each permutation basically gives rise to a cascade of other permutations. being that animal studies are useless for determining what psychedelic effects a human might experience from this or that chemical, he tries the compounds himself, going from a low dose upwards. if he detects a psychedelic effect and it doesn't seem terribly toxic, he then has a group of friends who take them as well and describe their experiences. the first part of the book is supposedly a novelization (presumably to provide plausible deniability in case any law enforcement agencies wanted to come after him), first in his voice, of his career as a psychedelic chemist, then in his second wife's voice, of her experience meeting him and joining him in testing his creations. Similarly, in the Shulgins’ book PiHKAL, pleasant experiences are described in the 16 to 24 mg range, but harrowing and more challenging trips were occasioned by higher doses, such as this trip report authored by someone who took a 64 mg dose:

Warning: Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them). Talaie, H.; Panahandeh, R.; Fayaznouri, M. R.; Asadi, Z.; Abdollahi, M. (2009). "Dose-independent occurrence of seizure with tramadol". Journal of Medical Toxicology. 5 (2): 63–67. doi: 10.1007/BF03161089. ISSN 1556-9039. Shulgin in this book told his life's story and how he got interested in the things that made him famous (it has to do with the placebo effect and the power of the mind); how he met his wife, who co-authored this work with him; he described his little psychedelic sessions with friends in a very affectionate and effective way. Inclusion of 4-bromo-2,5-dimethoxyphenethylamine (2C -B) in Schedule II of the Convention on Psychotropic Substances of 1971". United Nations Office on Drugs and Crime (UNODC). March 20, 2001. CND Dec.44/1 . Retrieved December 10, 2019. How I rate this book is on a scale of 0 to awesome. But that doesn't mean it is without flaws or strangeness.No sentence summarizes this book better than the Mythbusters quote, "Remember kids, the only difference between screwing around and science is writing it down." Shulgin and his experimental group conducted countless experiments on his creations, all while documenting the dosages, effects, and durations. As anyone who has done psychedelics knows, recounting the experience is at least as hard as remembering dreams. This, alone, makes the data extremely impressive.

While reading this book I attended a lecture given by Nobel laureate Kary Mullis. Kary Mullis received the Nobel Prize for Chemistry in 1993 for the development of PCR. During his lecture he commented on the first scientific paper he published in Nature, in 1968. He described it as a sophomoric astrophysical hypothesis called "The Cosmological Significance of Time Reversal." He told the audience he ate LSD while writing it. Needless to say Nature is still probably a little embarrassed about publishing it. MDMA - MDMA strongly amplifies the physical, visual, and cognitive effects of 2C-B. This combination is reported to produce strong sensations of euphoric pleasure manifested through distinct body highs, headspaces and uniquely colorful visuals. The synergy between these substances is unpredictable, and it is advised to start with markedly lower doses than one would take for both substances individually. This combination may increase the neurotoxic effects of MDMA, based on its similarity to LSD, which has been found to increase MDMA neurotoxicity. [16]

Phenethylamines I Have Known And Loved:

It feels appropriate to begin with a quote The second half of the book is the synthesis, step by step, that Shulgin used to make each of the over 200 sympathomimetic phenethylamines/amphetamines in the book.

While 2C-B has been reported as having the potential to produce transpersonal states, they are reported to occur less consistently or intensely than with classic psychedelics such as psilocybin mushrooms, mescaline, LSD, or DMT. Drugs/plants contain no experience, they can only open doors through which experience can occur. But the only thing you encounter is part of yourself I believe this book is a must-read for anybody who has any interested in psychedelic substances and the drug war. Shulgin has manufactured many substances that are falling into recreational use today, and only by learning more about these drugs can we ensure that people are able to make safe and informed decisions about the substances that they put into their body while trying to explore their mind.

The Chemistry Continues

B (Nexus) Reappears on the Club Drug Scene" (PDF). Information Bulletin. Drug Enforcement Agency (DEA). May 2001. 2001-L0424-002. different psychedelic compounds (most of which Shulgin discovered himself), including detailed synthesis instructions, bioassays, dosages, and other commentary. Alexander Shulgin; Ann Shulgin (1991). PiHKAL: A Chemical Love Story. United States: Transform Press. ISBN 0963009605. OCLC 1166889264. B was first synthesized and tested for psychoactivity in 1974 by the American chemist and psychedelic researcher Alexander Shulgin, who was investigating novel psychedelic compounds based on the chemical structure of mescaline.