Adults, the elderly and children 16 years and over: One sachet every 4–6 hours as required. Do not take more than 4 sachets in 24 hours. Women who are breastfeeding. It's not known if phenylephrine passes into breast milk, or its effect on a nursing infant. When taken by mouth, decongestants such as phenylephrine can also temporarily decrease the production of breast milk with just one or two doses. Ask your doctor or pharmacist for further advice. There may be an increased risk of side effects on the kidneys if ibuprofen is taken in combination with any of the following medicines: Kumar S, Rex DK. Failure of physicians to recognize acetaminophen hepatotoxicity in chronic alcoholics. Arch Intern Med. 1991;151:1189-91.

There are many other medicines available for the treatment of cold and flu. Many of these will also contain ibuprofen or phenylephrine in their active ingredients. Women who are pregnant. (Phenylephrine has blood vessel constricting effects that could restrict blood supply to the placenta, or cause problems for women with a history of pre-eclampsia. Ask your doctor or pharmacist for further advice on how to treat cold and flu symptoms during pregnancy.)

hydrochloride 6.1 mg. Night capsule contains Paracetamol 500 mg, Phenylephrine hydrochloride 6.1 mg. Indications: For the relief of Prostaglandins are produced by the body in response to injury and certain diseases. One of their actions is to sensitise nerve endings, so that when that area is stimulated it causes pain (presumably to prevent us from causing further harm to the area). As paracetamol reduces the production of these nerve sensitising prostaglandins it's thought it may increase our pain threshold, so that although the cause of the pain remains, we can feel it less. Healthcare (UK) Ltd, Hull, HU8 7DS. Information about this product, including adverse reactions, precautions, contra-indications, Adults aged 16 years and over should take two capsules every four to six hours as necessary, up to a maximum of four doses in 24 hours. Do not take more than eight capsules in 24 hours. antiplatelet medicines to reduce the risk of blood clots or 'thin the blood', eg dipydridamole, clopidogrel, low-dose aspirin

If you're taking medicines for high blood pressure you shouldn't take Lemsip max day & night cold & flu relief, because the decongestant may make your blood pressure medicine less effective. Lemsip cough max for mucus cough and cold capsules and hot drinks contain the painkiller paracetamol, a cough expectorant called guaifenesin and a decongestant called phenylephrine hydrochloride. These three active ingredients have different actions to relieve your symptoms.

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Common (1% to 10%): Dyspnea, abnormal breath sounds, pulmonary edema, hypoxia, pleural effusion, stridor, wheezing, coughing [ Ref] Cardiovascular Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine. Ibuprofen is a type of medicine called a non-steroidal anti-inflammatory drug (NSAID). It is a simple painkilling medicine used to relieve mild to moderate pain, inflammation and fever. This medicine is not recommended for use during pregnancy. In particular, it should not be taken in the third trimester, as ibuprofen may delay labour, increase the length of labour and cause complications in the newborn baby. Phenylephrine has blood vessel constricting effects that could restrict blood supply to the placenta, or cause problems for women with a history of pre-eclampsia. Some evidence suggests that NSAIDs should also be avoided by women attempting to conceive, as they may temporarily reduce female fertility during treatment and may also increase the risk of miscarriage or malformations. Seek further medical advice from your doctor, pharmacist or midwife.

It is safe to take Lemsip cold & flu sachets with ibuprofen or aspirin. However, do not take them with co-codamol, co-dydramol or Tramacet because these contain paracetamol.Guccione JL, Zemtsov A, Cobos E, Neldner KH. Acquired purpura fulminans induced by alcohol and acetaminophen - successful treatment with heparin and vitamin-k. Arch Dermatol. 1993;129:1267-9. Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with the ingredients of Lemsip max day & night cold & flu relief. Just because a side effect is stated here doesn't mean that all people using this medicines will experience that or any side effect.

reactions, precautions, contra-indications, and method of use can be found at: http://www.medicines.org.uk/emc/medicine/23352 for All-in-One Kaysen GA, Pond SM, Roper MH, Menke DJ, Marrama MA. Combined hepatic and renal injury in alcoholics during therapeutic use of acetaminophen. Arch Intern Med. 1985;145:2019-23. An overdose of paracetamol is dangerous and capable of causing serious damage to the liver and kidneys. Get immediate medical advice if you or someone you know takes too much paracetamol, even if you feel well, because of the risk of delayed, serious liver damage.The antidiabetic medicines exenatide, lixisenatide and liraglutide may slow down the absorption of paracetamol into the bloodstream, so it might take longer to work if you're using one of these medicines to treat your diabetes. Ask your pharmacist for more advice. If you take Lemsip cough max for mucus cough and cold in the hour before or the six hours after taking colestyramine, the paracetamol is likely to be less effective. This is because colestyramine reduces the absorption of paracetamol from the gut.