You can take cetirizine with or without food, but always take the tablets or capsules with a drink of water, milk or squash. Swallow them whole. Do not chew them. Loratadine is usually recommended if you need to take an antihistamine in pregnancy. Loratadine or cetirizine are usually OK to take while breastfeeding. Cetirizine is classed as a non-drowsy antihistamine, but some people still find it makes them feel quite sleepy. In addition to its anti-H 1 effect, cetirizine was shown to display anti-allergic activities: at a dose of 10 mg once or twice daily, it inhibits the late phase recruitment of eosinophils, in the skin and conjunctiva of atopic subjects submitted to allergen challenge.

Histamine-1 receptors are located in your airways (breathing tubes), blood vessels, stomach, and esophagus (throat area). Allergens, such as pollen or pet fur can stimulate these receptors, causing the release of histamine, which results in symptoms such as a rash, sneezing, a runny nose, or a narrowing of the airways (also called bronchoconstriction). Histamine-1 receptors are also found in the brain and spinal cord and first-generation antihistamines (sedating antihistamines) can cross through the blood/brain barrier into the brain and act on these receptors, causing sleepiness ( sedation), and drowsiness. What are antihistamines used for?Undesirable effects are described according to MedDRA System Organ Class and by estimated frequency based on post-marketing experience. have an allergy to peanuts or soya – some brands of cetirizine capsules (but not tablets) contain soya In addition to the adverse reactions reported during clinical studies and listed above, the following undesirable effects have been reported in post-marketing experience.

diarrhoea – drink plenty of water or other fluids if you have diarrhoea. Speak to a pharmacist if you have signs of dehydration, such as peeing less than usual or having dark, strong-smelling pee. Do not take any other medicines to treat diarrhoea without speaking to a pharmacist or doctor.

One of the most commonly used medications to help with the management of canine allergies are antihistamines, which can help to reduce skin irritation, inflammation, hayfever-like symptoms and other presentations of the allergy. In this article, we will look at how antihistamines work in more detail, and why they can, in some cases, help to keep your dog with allergies more comfortable. Read on to learn more. How do antihistamines work? Cetirizine comes as tablets and capsules (10mg) and as a liquid medicine (labelled either 5mg/5ml or 1mg/1ml). Do not use the tablets after the expiry datewhich is stated on the label. The expiry daterefers to the last day of that month. Correctly dosing antihistamines is determined by things like the weight and condition of your dog, and the response that they show once treatment with the medication has begun.

The aim of this is to desensitise the immune system so that it doesn't produce such a severe reaction. If you remember more than 4 hours after, do not give the missed dose. Instead, wait until the next dose and carry on as normal. If you no longer have the leaflet that came with your medicine, you can search for an online version of it using our medicines A to Z. Hepatic impairment: Patients with chronic liver diseases (hepatocellular, cholestatic, and biliary cirrhosis) given 10 or 20 mg of cetirizine as a single dose had a 50 % increase in half-life along with a 40 % decrease in clearance compared to healthy subjects.Some cases of memory loss and/or impairment have also been reported. In very rare casespeople have thought about committing suicideand if you feel this way then stop taking thetablets and see your doctor allacan was not mutagenic in the Ames test, and not clastogenic in the human lymphocyte assay, the mouse lymphoma assay, and in vivo micronucleus test in rats . sore throat – if you're 16 and over, you can try gargling with an aspirin solution (1 soluble aspirin tablet dissolved in half a glass of water) or use a pain-relieving mouthwash such as Oraldene. If your symptoms last longer than a week, ask your pharmacist or doctor for advice. Children under 16 must not be given aspirin. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take cetirizine film-coated tablet.

Histamine is normally released when your body detects something harmful, such as an infection. It causes blood vessels to expand and the skin to swell, which helps protect the body. first-generation antihistamines (also known as sedating antihistamines because they all cause drowsiness)Pruritus and/or urticaria may occur when cetirizine is stopped, even if those symptoms were not present before treatment initiation. In some cases, the symptoms may be intense and may require treatment to be restarted. The symptoms should resolve when the treatment is restarted. The extent of absorption of cetirizine is not reduced with food, although the rate of absorption is decreased. The extent of bioavailability is similar when cetirizine is given as solutions, capsules or tablets.