If you talk to the salespeople, they always want to run on what’s selling already. They say ride the wave, but I don’t believe in riding the wave. Everyone else is on the wave and that wave is going to come down – so what’s the point?”​ It exfoliates by loosening the bonds between dead and hard skin cells to reveal a more radiant complexion. Additionally, it works on the hydration of the dry skin. The combination of lactic acid with retinol gives a synergistic improvement in the symptoms of acanthosis nigricans. One of the many noteworthy aspects of retinol is that it stimulates skin cell turnover, which is manifested as a sort of "exfoliating" effect. Dull and dry skin makes way for new, brighter, and more even-toned skin, armed with increased levels of collagen and elastin. The newer skin is stronger and smoother and has fewer overall imperfections. Thus, even relatively "problem-free" skin can have radiating effects from retinol.

One of the main ingredients is urea, which can be an irritant for sensitive skin. It also has tea tree oil (which I'm pretty sure is where most of the scent comes from), which can also cause irritation dryness and rashes, and since it isnt a common ingredient, you may also be allergic and not know. I'd reccommend doing a test patch for a 2-3 days, before fully committing to slathering it on your affected areas, especially if they're in sensitive regions. If still worried, try doing it only once a day instead of the reccomended twice to see how those areas react. You also do not need as much as you may think! A little bit goes a long way, and leaving excess urea and tea tree oil just sitting ON the skin might promote some of those adverse reactions, use as little as possible and rub it all in!It has topped Fixderma’s wide-ranging portfolio, which includes vitamin C serums, acne treatments, and sunscreens – suggesting that acanthosis nigricans might be a problem faced by more people that previously thought. One of Fixderma’s latest products and one that is rising to the top of the charts fast is Foobetik, a foot cream that has been formulated especially for people who suffer from diabetes. Sometimes you experience it when you’re very tired and it makes it hard for you to fall asleep. So initially it was made for diabetics, but we found that many people very happy with Foobetik,”​ said Mehrotra. Water (Aqua), Lactic Acid, Urea, Prunus Amygdalus Dulcis (Sweet Almond) Oil, Lecithin, Retinol, Water Glycerin, Aloe Barbadensis Leaf Juice, Glycerine, Cetearyl Alcohol & Ceteareth-20, Simmondsia Chinensis (Jojoba) Seed Oil, Phenoxyethanol, Ethylhexylglycerin, Melaleuca Alternifolia (Tea Tree) Leaf Oil, Zinc Oxide, Camphor, Xanthan Gum. The first main difference is that while TiO2 gives a nice broad spectrum protection, Zinc Oxide has an even nicerand even broader spectrum protection. It protects against UVB, UVA II, and UVA I almost uniformly, and is considered to be the broadestrange sunscreen available today.

In the highly trend-driven skin care market, Shaily Mehrotra is not interested in following hashtags. The launch of Foobetik was also accompanied by a similar light-hearted commercial fronted by actor Rushad Rana.

Why is it Different?

As for the disadvantages, Zinc Oxide is also not cosmetically elegant. It leaves a disturbing whitish tint on the skin , although , according to a 2000research paper by Dr. Pinnell, it's slightlyless white than TiO2. Still, it's white and disturbing enough to use Zinc Oxide nanoparticles more and more often. Mehrotra highlighted that such advertising campaigns were extremely crucial to the success of the products. It'salso highly stableand non-irritating. So much sothat Zinc Oxide also counts as a skin protectant and anti-irritant. It's also often used to treat skin irritationssuch as diaper rash. While the cream was developed for diabetics, the company discovered that many people have experienced the same uncomfortable tingling sensation even though they are not diabetic.

Today, 60% of Fixderma’s total sales are dominated by Nigrifix. "That's because there's nothing like it out there,"​ said Mehrotra. The founder and CEO of Fixderma from India told CosmeticsDesign-Asia​ that being dictated by buzzwords was a futile endeavour. Mother Nature also created wax esters but for a totally different purpose. Chemically, a wax ester is a fatty acid + a fatty alcohol, one long molecule. Wax esters are on the outer surface of several plant leaves to give them environmental protection. 25-30% of human sebum is also wax esters to give uspeople environmental protection. UREA is a humectant due to its ability to retain moisture by binding to water. When urea is applied to the skin, it is able to penetrate into the stratum corneum to further enhance water absorption. At high concentrations, urea is a keratolytic and helps to loosen scaly, dead skin allowing for exfoliation and improve cellular turnover. By retaining moisture and enhancing the skin’s renewal process, urea helps to ultimately strengthen the stratum corneum barrier function to fight the scaly and leathery skin.LACTIC ACID is a hydrating alpha hydroxy acid (AHA) commonly derived from milk, but there are alternative vegan sources, like fermented corn starch, beets, and other sugar-rich foods. According to Mehrotra, the launch of Nigrifix has been tremendously successful. The company has observed double-digit growth month after month.

Regarding skincare and tea tree oil, its most well-known effect is probably being a well established anti-acne ingredient. Multiple studies confirm that TTO is effective against the evil acne-causingbacteria called P. acnes and the effectiveness of 5% TTO gel is comparable to the gold standard anti-acne treatment,5% Benzoyl Peroxidelotion. You need to be a bit more patient with TTO, though, as its effects come slower but also with fewer side effects.However, Foobetik does not just moisturise the skin, but also maintains the temperature, as diabetics tend to have warmer feet. Furthermore, it also helps to soothe an uncomfortable tingling sensation associated with diabetes. Instead, the company’s product development process, which is headed largely by Mehrotra, focuses on solving problems that are not commonly discussed. RETINOL is considered one of the first-line treatment option for acanthosis nigricans. This vitamin A based ingredient is the most used and most studied compound for anti-ageing. Third, jojoba oil moisturizes the skin through a unique dual action:on the one hand, it mixes with sebum and forms a thin, non-greasy, semi-occlusive layer; on the other hand, it absorbs into the skin through pores and hair follicles thendiffuses into the intercellular spaces of the outer layer of the skin to make it soft and supple. It’s an underlying condition of ​ polycystic ovarian disease, obesity, or maybe even genetics,” ​explained Mehrotra.