Derks, Hans: History of the Opium Problem: The Assault on the East, ca. 1600–1950. Sinica Leidensia, 105. Leiden: Brill, 2012. ISSN 0169-9563. ISBN 978-90-04-22158-1 a b c d e Alfred W. McCoy. "Opium History, 1858 to 1940". Archived from the original on April 4, 2007 . Retrieved May 4, 2007.

The poppy genome contains 51,213 genes encoding proteins distributed 81.6% in 11 individual chromosomes and 18.4% remaining in unplaced scaffolds. [11] In addition, 70.9% of the genome is made up of repetitive elements, of which the most represented are the long terminal repeat retrotransposons. This enrichment of genes is related to the maintenance of homeostasis and a positive regulation of transcription. [11] Benjamin Pui-Nin Mo & E. Leong Way (October 1, 1966). "An Assessment Of Inhalation As A Mode Of Administration Of Heroin By Addicts". Journal of Pharmacology and Experimental Therapeutics. 154 (1): 142–151. PMID 5924312 . Retrieved June 6, 2007. Opium smoking began as a privilege of the elite and remained a great luxury into the early 19th century. However, by 1861, Wang Tao wrote that opium was used even by rich peasants, and even a small village without a rice store would have a shop where opium was sold. [47] The genes responsible for the conversion of (S) -reticuline to thebaine are found on chromosome 11.

Pharmacy product

Xiao, Shuiyuan; Yang, Mei; Zhou, Liang; Hao, Wei (February 2015). "Transition of China's drug policy: problems in practice". Addiction. 110 (2): 193–4. doi: 10.1111/add.12689. PMID 25602038. Santella, Thomas M.; Triggle, D. J. (2009). Opium. Facts On File, Incorporated. p.8. ISBN 9781438102139. Ahmad, Diana L. The Opium Debate and Chinese Exclusion Laws in the Nineteenth-century American West (University of Nevada Press, 2007). Drugs and Racism in the Old West.

a b c Yangwen Zheng (2003). "The Social Life of Opium in China, 1483–1999". Modern Asian Studies. 37 (1): 1–39. doi: 10.1017/S0026749X0300101X. S2CID 146582691.P. somniferum is susceptible to several fungal, insect and virus infections including seed borne diseases such as downy mildew and root rot. The use of pesticides in combination to cultural methods have been considered as major control measures for various poppy diseases. [18] Opium timeline". The Golden Triangle. Archived from the original on April 20, 2009 . Retrieved September 13, 2009. Chouvy, P.A. (2009). "Opium. Uncovering the Politics of the Poppy, London, I.B. Tauris (Cambridge, Harvard University Press: 2010)". Archived from the original on October 26, 2011.

Musto, David F. The American Disease: Origins of Narcotic Control. New York: Oxford University Press, 1987. a b c d e f g Dikotter, Frank (2004). Narcotic Culture: A History of Drugs in China. Hurst. p.3. ISBN 978-0226149059.Ouchterlony, John (1844). The Chinese war: an account of all the operations of the British forces from the commencement to the Treaty of Nanking. London: Saunders and Otley. Ladenburg, Thomas (1974). "Chapter 1, The French in Indochina" (PDF). University of Houston. Archived (PDF) from the original on March 1, 2023 . Retrieved March 21, 2023. Papaver somniferum is an annual herb growing to about 100 centimetres (40 inches) tall. The plant is strongly glaucous, giving a greyish-green appearance, and the stem and leaves bear a sparse distribution of coarse hairs. The large leaves are lobed, the upper stem leaves clasping the stem, [7] the lowest leaves with a short petiole. [8] :40 The flowers are up to 3–10cm (1–4in) diameter, normally with four white, mauve or red petals, sometimes with dark markings at the base. The fruit is a hairless, rounded capsule topped with 12–18 radiating stigmatic rays, or fluted cap. [9] All parts of the plant exude white latex when wounded. [7] :93 [10] :32 John Rennie (March 26, 2007). "When a woman ruled Chinatown". Tower Hamlets Newsletter. Archived from the original on February 10, 2010 . Retrieved May 12, 2007. Julius Berendes (1902). "De Materia Medica" (in German). Archived from the original on February 8, 2007 . Retrieved May 10, 2007.

Dioscorides,Introduction to The Herbal of Dioscorides the Greek Poppy crop from the Malwa in India (probably Papaver somniferum var. album [1]) Papaver somniferum, commonly known as the opium poppy [2] or breadseed poppy, [3] is a species of flowering plant in the family Papaveraceae. It is the species of plant from which both opium and poppy seeds are derived and is also a valuable ornamental plant grown in gardens. Its native range was east of the Mediterranean Sea, but now is obscured by ancient introductions and cultivation, being naturalized across much of Europe and Asia.

From the earliest finds, opium has appeared to have ritual significance, and anthropologists have speculated ancient priests may have used the drug as a proof of healing power. [11] In Egypt, the use of opium was generally restricted to priests, magicians, and warriors, its invention is credited to Thoth, and it was said to have been given by Isis to Ra as treatment for a headache. [1] A figure of the Minoan "goddess of the narcotics", wearing a crown of three opium poppies, c. 1300 BCE, was recovered from the Sanctuary of Gazi, Crete, together with a simple smoking apparatus. [14] [15] Opiates (e.g., morphine, codeine, and thebaine) exert their main effects on the brain and spinal cord. Their principal action is to relieve or suppress pain. The drugs also alleviate anxiety; induce relaxation, drowsiness, and sedation; and may impart a state of euphoria or other enhanced mood. Opiates also have important physiological effects: they slow respiration and heartbeat, suppress the cough reflex, and relax the smooth muscles of the gastrointestinal tract. Opiates are addictive drugs; they produce a physical dependence and withdrawal symptoms that can only be assuaged by continued use of the drug. With chronic use, the body develops a tolerance to opiates, so that progressively larger doses are needed to achieve the same effect. The higher opiates—heroin and morphine—are more addictive than opium or codeine. Opiates are classified as narcotics because they relieve pain, induce stupor and sleep, and produce addiction. The habitual use of opium produces physical and mental deterioration and shortens life. An acute overdose of opium causes respiratory depression which can be fatal. Australia (Tasmania), Turkey and India are the major producers of poppy for medicinal purposes and poppy-based drugs, such as morphine or codeine. [38] [15] The New York Times reported, in 2014, that Tasmania was the largest producer of the poppy cultivars used for thebaine (85% of the world's supply) and oripavine (100% of the world's supply) production. Tasmania also had 25% of the world's opium and codeine production. [4] Restrictions [ edit ] Opium poppy fields near Metheringham, Lincolnshire, England