There is some evidence in humans that melatonin may help reduce anxiety and promote sedation before medical procedures. Side effects in humans can include sleepiness, headaches, and gastrointestinal upset. Estelles G, Mills D. Signs of travel-related problems in dogs and their response to treatment with dog-appeasing pheromone. Veterinary Record. 2006;159:143–148. MULTI-BILLION PROBIOTIC: This canine, feline, and pet friendly high count formula improves the microbial balance within the intestines and removes harmful pathogenic bacteria from the digestive system. Simply add a scoop to cat, dog or any pet food There are different natural substances that have been studied for their calming properties. “While these ingredients have been shown to have some calming effects in dogs, it's important to note that their effectiveness may vary depending on the individual dog and the specific situation in which they are used,” says Caos. Adaptil plug-in diffusers aerosolize the pheromone up to 700 square feet, and the Adaptil collar and Sentry’s Calming Collar evaporate the pheromone. Both the diffusers and collars last for about 30 days. Dog Anxiety Vests

Pankratz K, Korman J, Emke C, et al. Randomized, placebo-controlled prospective clinical trial evaluating the efficacy of the Assisi anti-anxiety device (Calmer Canine) for the treatment of canine separation anxiety. Frontiers in Veterinary Science. 2021;20(8):775092.

Features

Some situations can affect dogs in different ways but adult dogs, at any age, can benefit from support to help them cope with challenging situations.

Consistency. The Native Pet Calming Chews are light brown and have a natural shape and hard consistency. Because they’re natural, they’re not all the same shape.Palatability. Our dogs LOVED these chews! This supplement is one of the most palatable options on our list. Ingredients. Vetriscience treats contain L-theanine, which is known to help soothe canine anxiety. Colostrum is another active ingredient. Though there isn’t much research on it yet, it’s thought that some of the proteins in this milk for newborns can help induce calmness. Many things can affect a dog's anxiety or stress levels. Lifestyle changes, such as moving to a new house or long car journeys, can cause your dog to become anxious. If you go on holiday, whether with your dog or leaving them with a friend, this can be a stressful time for your dog too. Treatment with more than one drug at a time will often improve a dog’s response to sedation. Possible oral sedative combinations include:

Like people, dogs can suffer from several different kinds of anxiety. Because all calming products may not help all types of anxiety, it’s important to consider what type of anxiety affects your dog before choosing a product. L-theanine. L-theanine works by increasing serotonin and dopamine levels in the brain, which produces a calming effect. It’s the main ingredient in most calming supplements for dogs and can be used for a variety of anxious conditions. Give your dog a supplement about one hour before an anticipated anxious event. All dogs are different and there is no one treatment that works for all dogs,” says Chris Roth, in-house veterinarian at Pets Best. “It is going to be a trial-and-error process to see what works for your dog, and so you may need to try a few or combination of solutions to find what works best for your pet.” INTESTINAL & IMMUNITY BOOSTER: Improve your pets immune system daily to help them become more healthy and resistant to disease threats. Prime their well being, intestines and immune system with our hypoallergenic Digestion Pro enzyme support formula

Dog Pheromones

How much a calming aid works and how long those effects last depending on the specific product and your dog’s response to it. “Some natural calming aids, such as chamomile or valerian root, may take longer to have an effect and may last for a shorter period of time, typically a few hours,” says Caos.