Combining glucosamine and turmeric, as glucosamine sulfate 2KCL and CurcuWIN®, with other well-researched joint extracts and compounds, Flex also offers the most comprehensive, yet focused joint formula on the market. Here, you’ll find no synthetics, no shellfish-sourced ingredients, or artificial additives. Ultimately, no firm conclusions can be made on the effectiveness of glucosamine, chondroitin, or the two combined as a treatment for osteoarthritic pain or stiffness. Due to the large inconsistency in results and quality of available research, continued research is needed. Summary

After 6 months, chondroitin sulfate led to similar pain scores as celecoxib and significantly lower scores than the placebo. Thus, the authors concluded that chondroitin sulfate may be an effective pain remedy for those with knee osteoarthritis pain ( 10). Both chondroitin and methlysulfonylmethane, or MSM, are natural compounds that Are naturally found in joints. Bones are connected by joints, which allow us to move with ease. Joint damage can cause pain preventing you from doing the things you once loved. Many conditions lead to joint pain from aging to an untreated sports injury. A quality joint product may help repair existing tissue damage and also promote stronger joints, less susceptible to future degeneration. Medical Disclaimer: This product/supplement review is not intended to provide diagnosis, treatment, or medical advice. Please consult with a physician or other healthcare professional regarding any medical or health-related diagnosis or treatment options.

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When considering the use of herbal supplements, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements. Active 55+: regardless of your profession or recreational preferences, everyone ages and eventually succumbs to age-related joint degradation. Damlar İ et al. Effects of glucosamine-chondroitin combination on synovial fluid IL-1β, IL-6, TNF-α and PGE2 levels in internal derangements of temporomandibular joint. Med Oral Patol Oral Cir Bucal. 2015 May; 20(3): e278-e283. Several studies have found that glucosamine, chondroitin, and MSM help pain caused by osteoarthritis, while others found no benefit to taking the supplement.

Chondroitin is found in various parts of the body, including the skin, bone, ligaments and tendons.

Chondroitin supplements

N-acetyl glucosamine (NAG). Natural Medicines. https://naturalmedicines.therapeuticresearch.com. Accessed Oct. 24, 2020. Finally, a 2 1/2-year study in 407 women with overweight ages 50–60 found 1,500 mg/day of glucosamine sulfate to significantly decrease the risk of knee osteoarthritis compared with a placebo, suggesting that it may work as a preventive therapy ( 9). Chondroitin Much of joint pain can be attributed to inflammation of the synovia, making joint movement feel tender and painful.

But these popular joint supplement ingredients differ, both structurally and functionally. Here’s a brief description of each Glucosamine and Turmeric: Boswellia Extract– the boswellia serrate tree is usually found in India and its gum is considered important due to its effective anti-inflammatory and anti-arthritic properties. A randomized experiment in the Journal of Phytotherapy and Phytopharmacology concluded that this ingredient decreased knee pain and improved knee flexibility. Though there isn’t much research on the specific combination of glucosamine and turmeric, it’s important to take minimally effective dosages of each, to ensure enough formula space for all joint-support ingredients to work. Optimal Dosages of Turmeric and Glucosamine Glucosamine and chondroitin for the treatment of osteoarthritis Vasiliadis HS, Tsikopoulos K. Glucosamine and chondroitin for the treatment of osteoarthritis. World J Orthop 2017; 8(1): 1-11 [PMID: 28144573 DOI: 10.5312/wjo.v8.i1.1] https://www.wjgnet.com/2218-5836/full/v8/i1/1.htm/ Suryanarayana P et al. Effect of turmeric and curcumin on oxidative stress and antioxidant enzymes in streptozotocin-induced diabetic rat. Med Sci Monit. 2007 Dec; 13(12): BR286-92.Whereas glucosamine structurally supports connective tissue integrity within the joint, turmeric offers greater protection against joint-diminishing oxidative stress, inflammation, and enzymes. Two of the most popular joint support supplements are Glucosamine, an amino sugar naturally concentrated in joint tissues, and Turmeric, a superfood spice rich with antioxidant, anti-inflammatory curcuminoids.