Consider scopolamine, available in a prescription adhesive patch called Transderm Scop. Several hours before you plan to travel, apply the patch behind your ear for 72-hour protection. Talk to your health care provider before using the medicine if you have health problems such as glaucoma or urine retention. Try a cool flannel on your forehead, try to get fresh air on your face and do your best to find a way to rinse your mouth to get rid of the taste. Remember, if you give children medicines which cause drowsiness they can sometimes be irritable when the medicines wear off. On long journeys, try breaking the journey to have some fresh air, drink some cold water and, if possible, take a short walk. As some people will have a paradoxical reaction to Benadryl, make sure you try it out at home before taking it on the plane,” explains Dr. Gene Delaune, senior medical consultant for Allianz Travel Insurance.

Breathe deeply and slowly and, while focusing on your breathing, listening to music. This has been proved to be effective in clinical trials. Try listening to an audio book with your eyes closed. There is some evidence that distracting your brain with audio signals can reduce your sensitivity to the motion signals. Avoid strong smells, particularly petrol and diesel fumes. This may mean closing the window and turning on the air conditioning, or avoiding the engine area in a boat. For effective and convenient treatment, you need a washable, reusable, and highly recommended band, like the Sea-Band Anti-Nausea Acupressure Wristband, for example. Metoclopramide is a tablet used to speed up the emptying of your tummy. Slow emptying of the tummy is something that happens when you develop nausea and vomiting, so metoclopramide can help prevent this. It prevents nausea and vomiting quite effectively in some people. It can occasionally have unpleasant side-effects, particularly in children (in whom it is not recommended). Metoclopramide is often helpful for those who tend to have gastric reflux, those who have slow tummy emptying because of previous surgery, and those who have type 1 diabetes. Your GP will advise whether metoclopramide is suitable for you. Domperidone

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Focus on the horizon or on a distant, stationary object. Don't read or use electronic devices while traveling. Avoid heavy meals and do not drink alcohol before and during travelling. It may also be worth avoiding spicy or fatty food. That’s why it’s a good idea to pay attention to cleaning and maintenance. Besides, it is a straightforward process. All you have to do is add some mild soap on a damp cloth and wipe the surface of the band. When you are done scrubbing, let it air dry. Don't eat a heavy meal before travelling. Light, carbohydrate-based food like cereals an hour or two before you travel is best. Close your eyes (and keep them closed for the whole journey). This reduces 'positional' signals from your eyes to your brain and reduces the confusion.

Dr. Tiffany Otto Knipe is a pediatrician from WMP Boutique Pediatric Care in New York City. For children, she suggests a small dose of Benadryl (diphenhydramine) “as a last resort,” given 30 to 60 minutes prior to travel. And she notes the sleepy side effect isn’t always desirable. The potential for drowsiness “means that when you get to your destination your child might be too tired to enjoy it,” she says.

It is advisable not to watch moving objects such as waves or other cars. Don't look at things your brain expects to stay still, like a book inside the car. Instead, look ahead, a little above the horizon, at a fixed place.