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Plaquex is a treatment used for liver damage and has been studied in over 126 clinical studies involving over 8,300 patients in the past 38 years. Plaquex therapy is a cutting-edge, natural treatment that uses a special formula to dissolve plaque buildup in your arteries, improving blood flow and reducing the risk of heart disease. It can also improve your LDL cholesterol and triglycerides while increasing your beneficial HDL cholesterol levels. In this article, we’ll explore the benefits of plaquex therapy and explain how this innovative treatment can help you improve your cardiovascular health and help other conditions as well. What is Plaquex Therapy®? There is a close relationship between high cholesterol levels in the membranes of platelets and an increased tendency to adhesion and aggregation of platelets. 40 Deposits of platelets on vascular walls enhance the sensitivity of the wall towards substances released from platelets, increasing the wall permeability, leading to deposits of plasma constituents such as lipids in the injured wall. Plaquex, through the activation of LCAT, reduces the amount of cholesterol in the membranes of platelets, thereby reducing their tendency to adhesion and aggregation. During a 14 day trial with 500 mg PC/day given as infusions, the reactive platelet aggregation was reduced by 60%. A further study using 250mg/day over a period of 30 days in elderly patients with increased tendency to coagulation showed fibrinolytic acitivity to increase in the thrombo-elastogram. 1.5 g oral PC over 16 weeks increased serum 6-keto-PGF1, a stabilized metabolite of the antiaggregatory and vasodilatory prostaglandin PGI2 and a drop in Thromboxane levels. 49
Desreumaux, C., E. Dedonder, P. Dewsilly, G. Sezille, J.C. Fruchart: Effects of unsaturated fatty acids in phospholipids on the in vitro activation of the lipoprotein lipase and the triglyceride lipase Drug Res. 29 (1979) 1581-1583 Fakhri, O., E. Popov, Z. Gabbasov, H. Kurdanov, I. Gavrilov: Effect of Lipostabil on serum lipid levels, and platelet aggregation in patients with ICD and hyperlipoproteinemia. 8th Int. Symp. on Atherosclerosis, Rome Oct. 1988 Arsenio, L., P. Bodria, G. Magnati, A. Strata: Studio dell' attivita terapeutica della fosfatidilcolina in diabetici con associata iperdislipidemia. Clin. Ter. 114 (1985) 117-127 Plaquex therapy is also used to treat Atherosclerosis and is given to patients suffering from angina pectoris whose coronary arteries contain plaque deposits, but also in patients with carotid artery plaque and peripheral plaque in the legs, causing claudication pain when walking. It is also used to improve the function of the liver and kidneys, skin texture, and gut lining. How is Plaquex Therapy Administered?Initial studies of multiple EDTA infusions to treat CVD showed mixed results. Studies were too small, both individually and in aggregate, to exclude a small to moderate benefit or harm of chelation. A: No, Plaquex can't be mixed in saline solution as it saponifies. Only use Glucose or Dextrose 5 %, even in diabetic patients. Not only does the Plaquex® Formula effectively remove fatty and hardened plaque from blood vessels, but it also has applications for general anti-aging purposes. Many doctors have observed their patients looking younger and healthier after about 20 treatments. Additionally, the Plaquex® Formula can protect the stomach lining from NSAID damage and has been used to treat psoriasis patients.
Lipostabil has been in use since 1955 in over fifty countries mainly for this purpose. With time, an abundance of studies have been done not only on preventing and treating fatty embolism, but on the effect of phosphatidylcholine on cell membranes, liver disease, kidney disease, atherosclerosis, blood lipids, and psoriasis, as well as Neurodermatitis. There are studies showing benefits for ulcerative colitis, Crohn’s disease, diabetes and Alzheimer’s’ disease. Studies were done in Russia, Japan, Germany, and Italy as well as the USA and China. Given the prolonged timespan during which the extracted studies were conducted, numerous EDTA infusion regimens were used. Each infusion regimen used different minerals, EDTA salt, and EDTA dosage, resulting in a potential source of confounding for comparison between studies. Most studies (n=17) reported using Na 2EDTA as the chelating agent, with only one study using calcium Na 2EDTA. Similarly, dosage varied across studies, as some reported using a fixed EDTA dose for all patients, whereas others adjusted chelating agent dose based on body weight or glomerular filtration rate. No clear pattern emerged between EDTA dosage and patient improvement. Choice of minerals and amount of water present in the infusion may also have had a confounding effect. In studies examining renal function, a high amount of saline in the solution may have helped improve dehydrated patients, rather than EDTA chelation. Two studies that reported improved renal function did not indicate the solution components, but the improvement may have been related to the volume of crystalloid infused. Five studies reported outcomes associated with changes in vascular structure and function, including pulse wave velocity, left ventricular ejection fraction, and brachial artery diameter. One RCT, the multicenter PATCH (Program to Assess Treatment Strategies to Achieve Cardiac Health) study conducted in Alberta, Canada (n=84; diabetes prevalence, 15%), found no differences between chelation and placebo for any measured outcome, including time to ischemia, time to anaerobic threshold, and maximal oxygen consumption (Table 1).
Where Can I Get Plaquex Therapy Near Me in NYC?
Studies have shown that PC can prevent and reduce liver damage caused by carbon tetrachloride, ethanol, acetaminophen, and indomethacin. PC has also been shown to reduce fatty deposits in the liver and prevent or postpone liver cirrhosis. In the 1990s, the use of the Plaquex® Formula shifted to treating plaque deposits, often in combination with EDTA chelation infusions. The treatment proved so effective that it has become a treatment in its own right, with hundreds of doctors in the US and worldwide using Plaquex and treating tens of thousands of patients. Yes, Plaquex therapy is often administered intravenously (IV) to deliver the phosphatidylcholine directly into the bloodstream. This method is used to help improve blood flow, support the repair of cell membranes, and remove plaque from blood vessels. Learn More about Other Plaquex Applications
In addition, a further study reported most of its outcomes as noncontinuous and therefore was categorized as a qualitative study; however, the study also measured quality of life data on a continuous scale. The trial enrolled 1,708 patients who were randomly assigned to receive either chelation therapy or placebo. Chelation therapy consisted of 40 infusions of a solution containing disodium EDTA, ascorbate, B vitamins, and other components. Plaquex inhibits endocytosis in smooth muscle cells thereby preventing the formation of atherosclerotic plaque. Bowyer et al (69) described a highly significant inhibition of endocytosis in the smooth muscle cells of pig aortas after in vitro incubation with PC. According to the authors, these results suggest that PC inhibits atherogenic processes by reducing the endocytosis of plasma constituents. It also educes the accumulation of cholesterol in macrophages by 15-20%, thereby preventing the formation of foam cells. Similarly, cadmium has also been associated with reduced glutathione activity, cadmium‐induced cell death through apoptotic pathway activation, and DNA methylation, resulting in increased oxidative stress, inflammation, and endothelial cell death.A qualitative study of patients with diabetes and PAD or retinopathy reported ulcer healing, vision improvement, and reductions in insulin dependence in patients. Intervention: 500mL infusion consisting of up to 3g Na 2EDTA (adjusted downward based on estimated glomerular filtration rate, 7g ascorbic acid, 2g magnesium chloride, 100mg procaine hydrochloride, 2500U unfractionated heparin, 2mEq potassium chloride, 840mg sodium bicarbonate, 250mg pantothenic acid, 100mg thiamine, 100mg pyridoxine)
Of the studies that found no improvement following repeated EDTA treatment, only 2 reported prevalence of diabetes and both had ≤15% patients with diabetes. Other studies in patients with end‐stage PAD also found significant improvement, including the resolution of lower extremity gangrene and ulcers, increased pain‐free walking ability, improvement in quality of life, and the avoidance of lower extremity amputations (Figure 4). Peeters, H. , V. Blaton, B. Declercq, D. Vandamme: The Effect of essential phospholipids in the lipid and fattz acid pattern of lipoproteins in type II patients. 4. Int. Symp. Drugs Affect Lipid Metab. Philadelphia, September 1971 Patients had various diagnoses including: 1 patient with Schizophrenia, 1 patient with Alzheimer’s Disease and cerebral atrophy, 3 patients with cerebral atrophy, 10 patients with cardiovascular disease and/or cerebrovascular accident
Is Plaquex Therapy a Chelation?
On entering the body, heavy metals, including lead and cadmium, affect multiple cellular and molecular mechanisms and result in downstream vascular changes. For example, elevated lead levels may cause a reduction in antioxidant effects, such as reduced glutathione activity, paraoxonase inactivation, and impaired calcium signaling, resulting in decreased ability of the cell to clear reactive oxygen species and free radicals as well as elevated expression of inflammatory markers. Patients with cerebrovascular disease and had severe vertigo or dizziness showed large improvements and patients with senility showed improved mental faculties The formula for Plaquex requires a very specific type of Phosphatidylcholine base ingredient which is a well kept trade secret. Early practitioners proposed decalcification of atherosclerotic plaque as a possible mechanism for EDTA benefit. Although EDTA benefit in atherosclerotic disease is not standard of care, more recent investigations suggest that benefits of chelation may stem from removal of established cardiotoxic metals, such as lead or cadmium.
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