Gianturco, V., Bellomo, A., D'Ottavio, E., Formosa, V., Iori, A., Mancinella, M., Troisi, G., and Marigliano, V. Impact of therapy with alpha-lipoic acid (ALA) on the oxidative stress in the controlled NIDDM: a possible preventive way against the organ dysfunction? Arch.Gerontol.Geriatr. 2009;49 Suppl 1:129-133. View abstract.

Alpha lipoic acid (also called lipoic acid or thioctic acid) is an organosulfur compound found in the body and also synthesized by plants and animals. It’s present in every cell inside the body and helps turn glucose into “fuel” for the body to use for energy.

Are there interactions with herbs and supplements?

Another meta-analysis found that supplementation made a significant difference in i ncreasing glutathione levels, although this didn’t necessarily transfer to protection against diseases development. Alpha lipoic acid (ALA) is a fat-soluble, sulfur-containing, vitamin-like antioxidant. It is not a true vitamin because it can be synthesized in the body and is not necessary in the diet of animals. ALA functions in the same manner as many B-complex vitamins. Good sources of ALA are yeast and liver. 1, 2 Other sources include spinach, broccoli, potatoes, kidney, heart, and skeletal muscle. 3 History

A general dosage recommendation for alpha lipoic acid supplementation is between20–50 milligrams per day for adults. This amount seems to be beneficial for general preventative health. Two liopate enatiomers ( R and S) exist as a consequence of a chiral center at the C6 location; however only R-ALA is endogenously synthesized. 5 Based on the currently available evidence, when given intravenously at a dosage of 600 mg once daily over a period of three weeks, alpha lipoic acid leads to a significant and clinically relevant reduction in neuropathic pain (grade of recommendation A). It is unclear if the significant improvements seen after three to five weeks of oral administration at a dosage of >or= 600 mg daily are clinically relevant.When it comes to battling physical signs of aging on the skin, certain studies have found that topical treatment creams containing 5 percent alpha lipoic acid can help reduce fine lines caused by exposure to sun ways. ALA is thought to act as an anti-aging substance because it helps restore skin tissues and epidermal structure while battling free radicals. Gutin I. In BMI We Trust: Reframing the Body Mass Index as a Measure of Health. Soc Theory Health. 2018;16(3):256-271. doi:10.1057/s41285-017-0055-0 Kravchuk, IuA, Mekhtiev, S. N., Uspenskii, IuP, Grinevich, V. B., and Koblov, S. V. [Device laboratory and postmortem parallels in alcoholic hepatitis during combined therapy using thioctic (alpha-lipoic) acid]. Klin.Med (Mosk) 2004;82(6):55-57. View abstract. Chances are you’ve heard a lot about the many benefits of various antioxidants and high-antioxidant foods — fighting inflammation, helping to beat cancer and so much more — but have you ever wondered what exactly antioxidants are and how they work in the body?