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PubMed: Crocin from Kashmiri saffron (Crocus sativus) induces in vitro and in vivo xenograft growth inhibition of Dalton's lymphoma (DLA) in mice.
Main article: History of saffron A detail from the "Saffron Gatherers" fresco of the "Xeste 3" building. It is one of many depicting saffron; they were found at the Bronze Age settlement of Akrotiri, on the Aegean island of Santorini.PubMed: An open label, randomized, fixed-dose, crossover study comparing efficacy and safety of sildenafil citrate and saffron (Crocus sativus Linn.) for treating erectile dysfunction in men naïve to treatment. PubMed: Protective effect of saffron extract and crocin on reactive oxygen species-mediated high glucose-induced toxicity in PC12 cells. PubMed: Saffron (Crocus sativus) aqueous extract and its constituent crocin reduces stress-induced anorexia in mice. Be careful if you plan on ingesting anything made with saffron oil, such as a saffron extract supplement. If too much of the oil is ingested, it could be toxic. For example, while low doses may be safe during pregnancy, high doses of saffron may be linked to miscarriage, so pregnant women should use caution before consuming it.
PubMed: Crocetin prevents retinal degeneration induced by oxidative and endoplasmic reticulum stresses via inhibition of caspase activity.
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Overall, you might benefit from using saffron, whether the spice or oil form, if you have wounds that need to be treated, you need a mental health boost, or you would like glowing and toned skin. PubMed: Determination of some phenolic compounds in Crocus sativus L. corms and its antioxidant activities study. PubMed: Isolation and characterization of a first set of polymorphic microsatellite markers in saffron, Crocus sativus (Iridaceae).
May improve memory in adults with Alzheimer’s disease. Saffron’s antioxidant properties may improve cognition in adults with Alzheimer’s disease ( 29). PubMed: Saffron (Crocus sativus L.) increases glucose uptake and insulin sensitivity in muscle cells via multipathway mechanisms. PubMed: Effect of centrifugal ultrafiltration on the composition of aqueous extracts of saffron spice (Crocus sativus L.).Of course, it’s a bit more complicated than that. There are other things besides just foods that could be considered “super” as well, and adding those to your daily diet or health routines could bring even more benefits that are sure to keep you healthy and energetic on a daily basis. What Is Saffron Oil? As a dietary supplement, people can safely take up to 1.5 grams of saffron per day. However, only 30 mg of saffron per day have been shown to be enough to reap its health benefits ( 7, 17, 30).
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