Joined in 2023 
82 
63 About this deal
May treat certain symptoms of autism. A study in 29 young men with autism found that daily doses of 50–150 µmol of sulforaphane for 18 weeks improved symptoms of autism like social interaction and verbal communication ( 20). Traka MH, Melchini A, Coode-Bate J, et al. Transcriptional changes in prostate of men on active surveillance after a 12-mo glucoraphanin-rich broccoli intervention-results from the Effect of Sulforaphane on prostate CAncer PrEvention (ESCAPE) randomized controlled trial. Am J Clin Nutr. 2019;109(4):1133-1144. doi:10.1093/ajcn/nqz012 The cancer seemed to grow more in the men who had regular broccoli soup. This is in comparison to those who had soup with high and extra high levels of glucoraphanin. But the difference wasn’t big enough to say for sure that it was because of the soup. It may have been due to chance. Yuan GF, Sun B, Yuan J, Wang QM. Effects of different cooking methods on health-promoting compounds of broccoli. J Zhejiang Univ Sci B. 2009;10(8):580-588. doi:10.1631/jzus.B0920051 Rhonda notes that for someone people, even taking 1 tablet (10 mg) with a meal can result in stomach discomfort. Therefore, as an alternative, she mentions Avmacol may be kinder on the stomach. We discuss Avmacol more below.
Granted, I know supplements work on everyone differently but if you're struggling with typical aspie issues like having difficulty socializing, etc. this supplement is worth a try. We also talked about the fact that it’s virtually impossible to entirely avoid glyphosate exposure in the modern world. And because of the significant potential for harm, it’s important to take steps to mitigate the exposure we can’t avoid. This includes things like eating a nutrient-dense anti-inflammatory diet, exercising regularly, getting enough sleep, reducing our exposure to other toxins, etc. But I think it also includes consuming additional nutrients that can upregulate our body’s internal detoxification system, especially by activating Nrf2 and improving glutathione status.Rhonda said (on her last Tim Ferriss podcast) she consumes up to 4 ounces (113g) of broccoli sprouts a few times per week. In terms of consuming them, you’ll probably want to emulate Rhonda, who adds the sprouts to smoothies and blends them in her Blendtec– to mask the taste with other flavors. You want to avoid juicing, as this will discard the pre-biotic fiber that is beneficial to our gut microbiome. Setting aside the inconvenience of having to make the sprouts and the issues with sterilizing them, the elephant in the room is that you never know if the broccoli seeds you’re buying actually contain glucoraphanin, and that’s whether you’ll get any sulforaphane when you sprout the seeds or what dose you’ll get if you do. Another reason I like BrocElite is that they add another isothiocyanate to the capsule called phenyl isothiocyanate, or PEITC for short. I honestly think this podcast is going to win the award for acronyms. PEITC is not found in broccoli; it’s found in watercress, and it’s a sort of chemical cousin to sulforaphane. Research suggests that it has a synergistic effect. When it’s combined with sulforaphane, it yields a 30 percent greater activation of Nrf2 than sulforaphane alone. Made in France from non-GMO broccoli seeds via a patented four-step process, this is the creme de la creme of sulforaphane supplements.
NRF2 induces the expression of over 200 genes that fight inflammation and promote detoxification and longevity. It supports the production of multiple antioxidant enzymes (including the “master antioxidant” glutathione) to defend your cells from free radical damage. May improve constipation. In a 4-week study in 48 adults, eating 20 grams of sulforaphane-rich broccoli sprouts improved symptoms of constipation. No effect was found for alfalfa sprouts, which are sulforaphane-free ( 27). Sulforaphane is a sulfur-containing isothiocyanate found in broccoli, cauliflower, cabbage, kale, broccoli sprouts, Bok choy, and Brussels sprouts. Consuming sulforaphane in amounts found in cruciferous vegetables is considered safe with few — if any — side effects ( 8). Finally, even storage of broccoli in the open air as would occur during transport and in retail store environments or at a farmers market, let’s say, leads to a 55 percent loss of glucosinolates after just three days after harvest. And storage in plastic bags results in a similar loss over a period of seven days. So, for all these reasons, unfortunately, again, eating cruciferous vegetables like broccoli, cabbage, etc., whether they’re cooked or raw, is not a good strategy for increasing sulforaphane in the body. Now, this doesn’t mean that cruciferous vegetables don’t have tons of other benefits. I still recommend eating them. But it does mean that we can’t depend on them for getting enough sulforaphane to be therapeutic or to have a significant effect. So that leaves sprouting and supplementation as the only other methods, and each has pros and cons. Let’s talk about sprouting first.
Moderation team
We highly recommend the SMNutrition Sulforaphane Supplement for those looking for a powerful antioxidant and cellular health supplement.
Great Deal 
New Comment